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# A research work on the concept of dhatwagnipaka in an Ayurvedic perspective showed that prasadpaka can be compared with anabolic pathways and kittapaka with catabolic pathways.<ref>Vani G, Prasad JSRA. Concept of dhatvagnipaka in Ayurvedic perspective in comparison with tissue metabolism. Int J Res Ayurveda Pharm. 2016 May 5;7(2):92–7.</ref>
 
# A research work on the concept of dhatwagnipaka in an Ayurvedic perspective showed that prasadpaka can be compared with anabolic pathways and kittapaka with catabolic pathways.<ref>Vani G, Prasad JSRA. Concept of dhatvagnipaka in Ayurvedic perspective in comparison with tissue metabolism. Int J Res Ayurveda Pharm. 2016 May 5;7(2):92–7.</ref>
#In the research on role of dhatwagni in carcinogenesis, dhatvagni is related with gene mutation and disequilibrium (vishamaavastha) of [[agni]] leading to manifestation of cancer condition.<ref>Rao SD. DHATWAGNI VYAPARA IN CARCINOGENESIS. Anc Sci Life. 1994;14(1–2):61–7.</ref> The study further states that disequilibrium of [[agni]] causes improper digestion and metabolism leading to decreased or increased or irregular formation of tissues. This is observed in carcinogenesis where intermediate by-products are formed in place of normal protein. The state of irregular dhatvagni is the root cause of tumor.
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#In the research on role of dhatwagni in carcinogenesis, dhatvagni is related with gene mutation and disequilibrium (vishamaavastha) of [[agni]] leading to manifestation of cancer condition.<ref>Rao SD. Dhatwagni vyapara in carcinogenesis. Anc Sci Life. 1994;14(1–2):61–7.</ref> The study further states that disequilibrium of [[agni]] causes improper digestion and metabolism leading to decreased or increased or irregular formation of tissues. This is observed in carcinogenesis where intermediate by-products are formed in place of normal protein. The state of irregular dhatvagni is the root cause of tumor.
 
#In the work on location of physiological activities of dhatwagni and bhautikagni the physiological functioning of dhatvagni is described along with the pathologies in the respective [[dhatu]] due to the malfunctioning of dhatvagni.<ref>Kalpana D. Sathe.2016, Location of Physiological Activities of Dhatwagni And Bhautikagni. Int J Recent Sci Res. 7(2), pp. 9133-9136.</ref> This study concludes that the location of dhatvagni is in the respective tissue of particular [[srotas]] (transportation and transformation system) and cellular level.  Secondly, the dhatvagni activity and bhutagni activity can be correlated with catalyst of dhatusnehaparampara and dhatukshalan by bala production by bhautikagnipaka respectively.
 
#In the work on location of physiological activities of dhatwagni and bhautikagni the physiological functioning of dhatvagni is described along with the pathologies in the respective [[dhatu]] due to the malfunctioning of dhatvagni.<ref>Kalpana D. Sathe.2016, Location of Physiological Activities of Dhatwagni And Bhautikagni. Int J Recent Sci Res. 7(2), pp. 9133-9136.</ref> This study concludes that the location of dhatvagni is in the respective tissue of particular [[srotas]] (transportation and transformation system) and cellular level.  Secondly, the dhatvagni activity and bhutagni activity can be correlated with catalyst of dhatusnehaparampara and dhatukshalan by bala production by bhautikagnipaka respectively.
 
#Dhatvagni is considered in the synthesis of new tissue and yielding of energy for the functioning of existent tissue.<ref>A Brief Mention of Agni In Ayurveda, GJRA - Global Journal For Research Analysis(GJRA), GJRA | World Wide Journals [Internet]. [cited 2022 Jul 8]. Available from: https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/article/a-brief-mention-of-agni-in-ayurveda/MTEwOTg=/?is=1&b1=61&k=16</ref> Bhutagni acts on respective  [[mahabhuta]] portion and  dhatvagni acts on respective [[dhatu]]s for nutritional strength, complexion, and happy life.
 
#Dhatvagni is considered in the synthesis of new tissue and yielding of energy for the functioning of existent tissue.<ref>A Brief Mention of Agni In Ayurveda, GJRA - Global Journal For Research Analysis(GJRA), GJRA | World Wide Journals [Internet]. [cited 2022 Jul 8]. Available from: https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/article/a-brief-mention-of-agni-in-ayurveda/MTEwOTg=/?is=1&b1=61&k=16</ref> Bhutagni acts on respective  [[mahabhuta]] portion and  dhatvagni acts on respective [[dhatu]]s for nutritional strength, complexion, and happy life.
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