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==Recent researches on dhatvagni==
 
==Recent researches on dhatvagni==
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# A research work on the concept of dhatwagnipaka in an Ayurvedic perspective showed that prasadpaka can be compared with anabolic pathways and kittapaka with catabolic pathways.<ref>Vani G, Prasad JSRA. CONCEPT OF DHATVAGNIPAKA IN AYURVEDIC PERSPECTIVE IN COMPARISON WITH TISSUE METABOLISM. Int J Res Ayurveda Pharm. 2016 May 5;7(2):92–7.</ref>
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# A research work on the concept of dhatwagnipaka in an Ayurvedic perspective showed that prasadpaka can be compared with anabolic pathways and kittapaka with catabolic pathways.<ref>Vani G, Prasad JSRA. Concept of dhatvagnipaka in Ayurvedic perspective in comparison with tissue metabolism. Int J Res Ayurveda Pharm. 2016 May 5;7(2):92–7.</ref>
 
#In the research on role of dhatwagni in carcinogenesis, dhatvagni is related with gene mutation and disequilibrium (vishamaavastha) of [[agni]] leading to manifestation of cancer condition.<ref>Rao SD. DHATWAGNI VYAPARA IN CARCINOGENESIS. Anc Sci Life. 1994;14(1–2):61–7.</ref> The study further states that disequilibrium of [[agni]] causes improper digestion and metabolism leading to decreased or increased or irregular formation of tissues. This is observed in carcinogenesis where intermediate by-products are formed in place of normal protein. The state of irregular dhatvagni is the root cause of tumor.
 
#In the research on role of dhatwagni in carcinogenesis, dhatvagni is related with gene mutation and disequilibrium (vishamaavastha) of [[agni]] leading to manifestation of cancer condition.<ref>Rao SD. DHATWAGNI VYAPARA IN CARCINOGENESIS. Anc Sci Life. 1994;14(1–2):61–7.</ref> The study further states that disequilibrium of [[agni]] causes improper digestion and metabolism leading to decreased or increased or irregular formation of tissues. This is observed in carcinogenesis where intermediate by-products are formed in place of normal protein. The state of irregular dhatvagni is the root cause of tumor.
 
#In the work on location of physiological activities of dhatwagni and bhautikagni the physiological functioning of dhatvagni is described along with the pathologies in the respective [[dhatu]] due to the malfunctioning of dhatvagni.<ref>Kalpana D. Sathe.2016, Location of Physiological Activities of Dhatwagni And Bhautikagni. Int J Recent Sci Res. 7(2), pp. 9133-9136.</ref> This study concludes that the location of dhatvagni is in the respective tissue of particular [[srotas]] (transportation and transformation system) and cellular level.  Secondly, the dhatvagni activity and bhutagni activity can be correlated with catalyst of dhatusnehaparampara and dhatukshalan by bala production by bhautikagnipaka respectively.
 
#In the work on location of physiological activities of dhatwagni and bhautikagni the physiological functioning of dhatvagni is described along with the pathologies in the respective [[dhatu]] due to the malfunctioning of dhatvagni.<ref>Kalpana D. Sathe.2016, Location of Physiological Activities of Dhatwagni And Bhautikagni. Int J Recent Sci Res. 7(2), pp. 9133-9136.</ref> This study concludes that the location of dhatvagni is in the respective tissue of particular [[srotas]] (transportation and transformation system) and cellular level.  Secondly, the dhatvagni activity and bhutagni activity can be correlated with catalyst of dhatusnehaparampara and dhatukshalan by bala production by bhautikagnipaka respectively.
 
#Dhatvagni is considered in the synthesis of new tissue and yielding of energy for the functioning of existent tissue.<ref>A Brief Mention of Agni In Ayurveda, GJRA - Global Journal For Research Analysis(GJRA), GJRA | World Wide Journals [Internet]. [cited 2022 Jul 8]. Available from: https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/article/a-brief-mention-of-agni-in-ayurveda/MTEwOTg=/?is=1&b1=61&k=16</ref> Bhutagni acts on respective  [[mahabhuta]] portion and  dhatvagni acts on respective [[dhatu]]s for nutritional strength, complexion, and happy life.
 
#Dhatvagni is considered in the synthesis of new tissue and yielding of energy for the functioning of existent tissue.<ref>A Brief Mention of Agni In Ayurveda, GJRA - Global Journal For Research Analysis(GJRA), GJRA | World Wide Journals [Internet]. [cited 2022 Jul 8]. Available from: https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/article/a-brief-mention-of-agni-in-ayurveda/MTEwOTg=/?is=1&b1=61&k=16</ref> Bhutagni acts on respective  [[mahabhuta]] portion and  dhatvagni acts on respective [[dhatu]]s for nutritional strength, complexion, and happy life.
#A study of dhatvagni with special reference to hypothyroidism depicted that abnormality at the level of [[meda dhatu]] (medodhatvagni vikriti) may be the cause of endocrinal disturbance related to thyroid gland functions. Secondly the excessive illumination of dhatwagni may cause rise in anabolism and catabolism.<ref>Sharma DV, Sharir MDK. STUDY OF DHATWAGNI VIKRITI W.S.R. TO HYPOTHYROIDISM. World Journal of Pharmaceutical Research. 10(5):10.</ref> Another study showed that the the clinical features of low dhatvagni functions (dhatvagnimandya) like slower metabolism (agninasha),  pallor (pandutwam), oligomenorrhoea (artavanasha), cold intolerance (sheetaasatmya) etc. can be correlated with symptoms of Hypothyroidism.<ref>??</ref>
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#A study of dhatvagni with special reference to hypothyroidism depicted that abnormality at the level of [[meda dhatu]] (medodhatvagni vikriti) may be the cause of endocrinal disturbance related to thyroid gland functions. Secondly the excessive illumination of dhatwagni may cause rise in anabolism and catabolism.<ref>Sharma DV, Sharir MDK. Study of Dhatwagni vikriti W.S.R. to hypothyroidism. World Journal of Pharmaceutical Research. 10(5):10.</ref> Another study showed that the the clinical features of low dhatvagni functions (dhatvagnimandya) like slower metabolism (agninasha),  pallor (pandutwam), oligomenorrhoea (artavanasha), cold intolerance (sheetaasatmya) etc. can be correlated with symptoms of Hypothyroidism.<ref>??</ref>
 
#Selective production and transformation of [[dhatu]] is explained. Each dhatvagni synthesize and transform the constituents suitable to its particular [[dhatu]] as a part of selective action.<ref>Agrawal AK, Yadav CR, Meena MS. Physiological aspects of Agni. Ayu. 2010;31(3):395–8.</ref>   
 
#Selective production and transformation of [[dhatu]] is explained. Each dhatvagni synthesize and transform the constituents suitable to its particular [[dhatu]] as a part of selective action.<ref>Agrawal AK, Yadav CR, Meena MS. Physiological aspects of Agni. Ayu. 2010;31(3):395–8.</ref>   
 
#The inter-relationship between jatharagni and dhatvagni in the manifestation of different diseases is established. [[Agni]] are connected with each other and due to this relationship, vitiation of jatharagni results in vitiation of all the other [[agni]].<ref>Satani DKG, Raghvani H, Bhatt K. Interrelationship of Jatharagni and Dhatvagni in context to Dhatvagni Pradoshaj Vikaras. Journal of Ayurveda and Integrated Medical Sciences. 2017 Feb 28;2(01):180–5.</ref>  
 
#The inter-relationship between jatharagni and dhatvagni in the manifestation of different diseases is established. [[Agni]] are connected with each other and due to this relationship, vitiation of jatharagni results in vitiation of all the other [[agni]].<ref>Satani DKG, Raghvani H, Bhatt K. Interrelationship of Jatharagni and Dhatvagni in context to Dhatvagni Pradoshaj Vikaras. Journal of Ayurveda and Integrated Medical Sciences. 2017 Feb 28;2(01):180–5.</ref>  
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