| In a study, sixty-four non-dialysis CRF patients with stage IV or V at base line and having record of laboratory investigations of the preceding 6 months were studied. The treatment protocol included enemas (niruha-basti) containing 40 ml punarnavadi kwatha daily one hour before lunch for one month. Oral medications like gokshuradi guggulu, varunadi kwatha, rasayana churna, bhumyamalaki, shilajatwadivati, and chyavanaprasha were given for six months. Renal function tests (RFTs) were evaluated at various time points, i.e 6 months before baseline (TP -6), at baseline (TP 0), and after completion of 6 months of treatment (TP +6). After six months of Ayurvedic treatment, statistically and clinically significant improvements of eGFR, serum creatinine, blood urea, and hemoglobin and a significant shift to better CRF stages were observed in this study.<ref>Patel M, Patel M, Patel K, Wischnewsky M, Stapelfeldt E, Kessler CS, Gupta SN. Deceleration of Disease Progress Through Ayurvedic Treatment in Nondialysis Stages IV-V Patients with Chronic Renal Failure: A Quasi-Experimental Clinical Pilot Study with One Group Pre- and Postdesign and Two Premeasurements. J Altern Complement Med. 2020 May;26(5):384-391. doi: 10.1089/acm.2019.0419. Epub 2020 Mar 30. PMID: 32223566.</ref> | | In a study, sixty-four non-dialysis CRF patients with stage IV or V at base line and having record of laboratory investigations of the preceding 6 months were studied. The treatment protocol included enemas (niruha-basti) containing 40 ml punarnavadi kwatha daily one hour before lunch for one month. Oral medications like gokshuradi guggulu, varunadi kwatha, rasayana churna, bhumyamalaki, shilajatwadivati, and chyavanaprasha were given for six months. Renal function tests (RFTs) were evaluated at various time points, i.e 6 months before baseline (TP -6), at baseline (TP 0), and after completion of 6 months of treatment (TP +6). After six months of Ayurvedic treatment, statistically and clinically significant improvements of eGFR, serum creatinine, blood urea, and hemoglobin and a significant shift to better CRF stages were observed in this study.<ref>Patel M, Patel M, Patel K, Wischnewsky M, Stapelfeldt E, Kessler CS, Gupta SN. Deceleration of Disease Progress Through Ayurvedic Treatment in Nondialysis Stages IV-V Patients with Chronic Renal Failure: A Quasi-Experimental Clinical Pilot Study with One Group Pre- and Postdesign and Two Premeasurements. J Altern Complement Med. 2020 May;26(5):384-391. doi: 10.1089/acm.2019.0419. Epub 2020 Mar 30. PMID: 32223566.</ref> |