2,062
edits
Changes
Jump to navigation
Jump to search
Line 168:
Line 168: − − In a study, sixty-four non-dialysis CRF patients with stage IV or V at base line and having record of laboratory investigations of the preceding 6 months were studied. The treatment protocol included enemas (niruha-basti) containing 40 ml punarnavadi kwatha daily one hour before lunch for one month. Oral medications like gokshuradi guggulu, varunadi kwatha, rasayana churna, bhumyamalaki, shilajatwadivati, and chyavanaprasha were given for six months. Renal function tests (RFTs) were evaluated at various time points, i.e 6 months before baseline (TP -6), at baseline (TP 0), and after completion of 6 months of treatment (TP +6). After six months of Ayurvedic treatment, statistically and clinically significant improvements of eGFR, serum creatinine, blood urea, and hemoglobin and a significant shift to better CRF stages were observed in this study.<ref>Patel M, Patel M, Patel K, Wischnewsky M, Stapelfeldt E, Kessler CS, Gupta SN. Deceleration of Disease Progress Through Ayurvedic Treatment in Nondialysis Stages IV-V Patients with Chronic Renal Failure: A Quasi-Experimental Clinical Pilot Study with One Group Pre- and Postdesign and Two Premeasurements. J Altern Complement Med. 2020 May;26(5):384-391. doi: 10.1089/acm.2019.0419. Epub 2020 Mar 30. PMID: 32223566.</ref> Line 176:
Line 174: + + Line 182:
Line 182: − + − -by intact nephrons − -by other organs
no edit summary
Another study was conducted in 130 patients of diabetic nephropathy treated with oral administration of gokshuradi guggulu, bhumyamalaki, vasa and shilajatvadivati for 2 months. The data showed highly significant reduction in serum creatinine, blood urea and urinary excretion of albumin.<ref>Patel K, Gupta SN, Shah N. Effect of Ayurvedic management in 130 patients of diabetic nephropathy. Ayu. 2011;32(1):55-58. doi:10.4103/0974-8520.85727</ref>
Another study was conducted in 130 patients of diabetic nephropathy treated with oral administration of gokshuradi guggulu, bhumyamalaki, vasa and shilajatvadivati for 2 months. The data showed highly significant reduction in serum creatinine, blood urea and urinary excretion of albumin.<ref>Patel K, Gupta SN, Shah N. Effect of Ayurvedic management in 130 patients of diabetic nephropathy. Ayu. 2011;32(1):55-58. doi:10.4103/0974-8520.85727</ref>
[[File: EGFR.JPG|500px|'''Image 1: Estimated marginal means of eGFR'''|thumb]]
[[File: EGFR.JPG|500px|'''Image 1: Estimated marginal means of eGFR'''|thumb]]
[[File: Hemoglobin.JPG|500px|'''Image 2: Estimated marginal means of hemoglobin'''|thumb]]
[[File: Hemoglobin.JPG|500px|'''Image 2: Estimated marginal means of hemoglobin'''|thumb]]
In a study, sixty-four non-dialysis CRF patients with stage IV or V at base line and having record of laboratory investigations of the preceding 6 months were studied. The treatment protocol included enemas (niruha-basti) containing 40 ml punarnavadi kwatha daily one hour before lunch for one month. Oral medications like gokshuradi guggulu, varunadi kwatha, rasayana churna, bhumyamalaki, shilajatwadivati, and chyavanaprasha were given for six months. Renal function tests (RFTs) were evaluated at various time points, i.e 6 months before baseline (TP -6), at baseline (TP 0), and after completion of 6 months of treatment (TP +6). After six months of Ayurvedic treatment, statistically and clinically significant improvements of eGFR, serum creatinine, blood urea, and hemoglobin and a significant shift to better CRF stages were observed in this study.<ref>Patel M, Patel M, Patel K, Wischnewsky M, Stapelfeldt E, Kessler CS, Gupta SN. Deceleration of Disease Progress Through Ayurvedic Treatment in Nondialysis Stages IV-V Patients with Chronic Renal Failure: A Quasi-Experimental Clinical Pilot Study with One Group Pre- and Postdesign and Two Premeasurements. J Altern Complement Med. 2020 May;26(5):384-391. doi: 10.1089/acm.2019.0419. Epub 2020 Mar 30. PMID: 32223566.</ref>
==Possible modes of action==
==Possible modes of action==
*Reversal of pathology in mild affected units
*Reversal of pathology in mild affected units
*Adaptation
*Adaptation
*Compensation
*Compensation by intact nephrons/by other organs
Clinical Studies on effect of Ayurvedic treatment on dialysis dependent patients are under progress.
Clinical Studies on effect of Ayurvedic treatment on dialysis dependent patients are under progress.