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<p style="text-align:justify;">The Sanskrit term ‘Vipaka’ (also spelled as vipaaka or vipAka) means specific transformation or effect after digestion of a substance. Detailed and in-depth description of the process of metabolism is the key component of [[Ayurveda]] physiology as well as pathology. Almost all the pathologies occurring in the human body are caused due to imbalance or malfunctioning of metabolism governed by the [[agni]]. Thus, it is of utmost importance for every physician to know the function of [[agni]] in detail. The process of metabolism is divided into two main components i.e. avasthapaka and vipaka. Avasthapaka is the general process of catabolism needed for all food and medicines ingested orally. It involves three stages viz. madhura (sweet), amla (sour) and katu (pungent) avasthapaka. Avasthapaka refers to a series of changes that food undergoes in the gut ([[koshtha]]). [[Agni]] is responsible for digestion and metabolism. In the first stage of digestion (madhura avasthapaka), the food in stomach ([[amashaya]]) undergoes primary transformation. In the second stage (amla avasthapaka), the food undergoes vigorous digestion in duodenum and small intestine (pachyamanashaya). Amlabhava develops under the action of the acid medium. In the third stage (katu avasthapaka), absorption of water and electrolytes occurs in the large intestine. The faeces are formed after maximum water absorption (pari pandita pakwasya). Odoriferous products with pungent gases are also released (vayusyatkatubhavatah). [Cha.Sa.[[Chikitsa Sthana]] 15/9-11]
The Sanskrit term ‘Vipaka’ (also spelled as vipaaka or vipAka) means specific transformation or effect after digestion of a substance. Detailed and in-depth description of the process of metabolism is the key component of [[Ayurveda]] physiology as well as pathology. Almost all the pathologies occurring in the human body are caused due to imbalance or malfunctioning of metabolism governed by the [[agni]]. Thus, it is of utmost importance for every physician to know the function of [[agni]] in detail. The process of metabolism is divided into two main components i.e. avasthapaka and vipaka. Avasthapaka is the general process of catabolism needed for all food and medicines ingested orally. It involves three stages viz. madhura (sweet), amla (sour) and katu (pungent) avasthapaka. Avasthapaka refers to a series of changes that food undergoes in the gut ([[koshtha]]). [[Agni]] is responsible for digestion and metabolism. In the first stage of digestion (madhura avasthapaka), the food in stomach ([[amashaya]]) undergoes primary transformation. In the second stage (amla avasthapaka), the food undergoes vigorous digestion in duodenum and small intestine (pachyamanashaya). Amlabhava develops under the action of the acid medium. In the third stage (katu avasthapaka), absorption of water and electrolytes occurs in the large intestine. The faeces are formed after maximum water absorption (pari pandita pakwasya). Odoriferous products with pungent gases are also released (vayusyatkatubhavatah). [Cha.Sa.[[Chikitsa Sthana]] 15/9-11]
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Diet and drugs undergo some inevitable changes during digestion. This may not feel change in the taste of the ingested substance. The characters are modified by [[agni]] in such a way that the ingested foreign substance can be assimilated by the body. Even though some properties of the substance persist after digestion, the end outcome of the digestion is governed by the vipaka of the substance. This vipaka is ultimately governed by the [[agni]] of the individual. Thus, vipaka can be predicted only by logical inference after observing the action on various components of the body.
 
Diet and drugs undergo some inevitable changes during digestion. This may not feel change in the taste of the ingested substance. The characters are modified by [[agni]] in such a way that the ingested foreign substance can be assimilated by the body. Even though some properties of the substance persist after digestion, the end outcome of the digestion is governed by the vipaka of the substance. This vipaka is ultimately governed by the [[agni]] of the individual. Thus, vipaka can be predicted only by logical inference after observing the action on various components of the body.
 
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Vipaka mainly starts in stomach and duodenum (grahani), and is responsible for the ultimate effect of the food or medicine ingested. The effect in the time of avasthapaka is momentary and confined to the region of the process, while the effect of vipaka can be seen on the whole body. The concept of 'vipaka’ holds significant importance in ayurvedic approach of metabolism as well as pharmaco-therapeutics. Vipaka is one of the components of rasa panchaka i.e. pharmacodynamic attributes of the drug. Thus, comprehensive knowledge of vipaka is essential to attain excellence in preservation of health and management of diseases through [[Ayurveda]].
 
Vipaka mainly starts in stomach and duodenum (grahani), and is responsible for the ultimate effect of the food or medicine ingested. The effect in the time of avasthapaka is momentary and confined to the region of the process, while the effect of vipaka can be seen on the whole body. The concept of 'vipaka’ holds significant importance in ayurvedic approach of metabolism as well as pharmaco-therapeutics. Vipaka is one of the components of rasa panchaka i.e. pharmacodynamic attributes of the drug. Thus, comprehensive knowledge of vipaka is essential to attain excellence in preservation of health and management of diseases through [[Ayurveda]].
 
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