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''Kapha'' and ''vata'' gets vitiated due to the use of firm, heavy, hard, sweet, cold, unctuous, and ''abhishyandi'' (which increase discharges and cause obstruction) ingredients of diet, lack of physical exercise etc. not following preventive seasonal [[Panchakarma]] purification. Deranged excessively, aggravated, powerful both ''kapha'' and ''vata'' vitiates the susceptible body elements giving rise to ''granthi visarpa''. Thereafter the ''vata'' being occluded by ''kapha'' in its progress and disintegrates ''kapha'' in many ways and gradually giving rise to chain of glands, hardly suppurating and difficult to cure, in the habitats of ''kapha''.

[[Kapha]] and [[vata]] gets vitiated due to the use of firm, heavy, hard, sweet, cold, unctuous, and ''abhishyandi'' (which increase discharges and cause obstruction) ingredients of diet, lack of physical exercise etc. not following preventive seasonal [[Panchakarma]] purification. Deranged excessively, aggravated, powerful both [[kapha]] and [[vata]] vitiates the susceptible body elements giving rise to ''granthi visarpa''. Thereafter the [[vata]] being occluded by [[kapha]] in its progress and disintegrates [[kapha]] in many ways and gradually giving rise to chain of glands, hardly suppurating and difficult to cure, in the habitats of [[kapha]].

In a person having aggravated blood, vitiated ''kapha-pitta'' provoke blood giving rise to a series of glandular enlargements which are exceedingly painful, large or small or elongated or round and of red color, located in blood vessels, ligaments, flesh and skin. Being afflicted, complications arise like fever, diarrhea, cough, hiccup, dyspnea, emaciation disturbed consciousness, abnormal complexion, anorexia, indigestion, excess salivation, vomiting, fainting, breaking pain in body , excessive sleep, restlessness, malaise, the patient associated with these complications goes beyond the reach of all remedial measures and as such is rejectable. This is ''granthi visarpa''.[39]

In a person having aggravated blood, vitiated [[kapha]]-[[pitta]] provoke blood giving rise to a series of glandular enlargements which are exceedingly painful, large or small or elongated or round and of red color, located in blood vessels, ligaments, flesh and skin. Being afflicted, complications arise like fever, diarrhea, cough, hiccup, dyspnea, emaciation disturbed consciousness, abnormal complexion, anorexia, indigestion, excess salivation, vomiting, fainting, breaking pain in body , excessive sleep, restlessness, malaise, the patient associated with these complications goes beyond the reach of all remedial measures and as such is rejectable. This is ''granthi visarpa''.[39]

=== ''Upadrava'' (complications) ===

=== ''Upadrava'' (complications) ===