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== Metabolism and Development ==
 
== Metabolism and Development ==
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The asthi dhatu is formed from its predecessor adipose tissue ([[meda dhatu]]). The nourishing portion of adipose tissue ([[meda dhatu]]) and constituents of nutrient fluid (ahara rasa) are transformed into asthi dhatu by action of factors responsible for its metabolism (asthi dhatvagni). [[Agni mahabhuta]] and [[vayu mahabhuta]] play a major role in the solidification and roughness of asthi by acting upon [[Prithvi mahabhuta]] components of adipose tissue ([[meda dhatu]]).[Cha. Sa. [[Chikitsa Sthana]] 15/30]  
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The asthi dhatu is formed from its predecessor adipose tissue ([[meda dhatu]]). The nourishing portion of adipose tissue ([[meda dhatu]]) and constituents of nutrient fluid (ahara rasa) are transformed into asthi dhatu by action of factors responsible for its metabolism (asthi dhatvagni). [[Agni mahabhuta]] and [[vayu mahabhuta]] play a major role in the solidification and roughness of asthi by acting upon [[prithvi mahabhuta]] components of adipose tissue ([[meda dhatu]]).[Cha. Sa. [[Chikitsa Sthana]] 15/30]  
    
Porosity in bones are due to actions of [[vayu]] and [[akasha]] mahabhuta. [Cha. Sa. [[Chikitsa Sthana]] 15/30]
 
Porosity in bones are due to actions of [[vayu]] and [[akasha]] mahabhuta. [Cha. Sa. [[Chikitsa Sthana]] 15/30]
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There are total 360 well-formed asthi in human body. [Cha. Sa.[[Sharira Sthana]] 7/6].  
 
There are total 360 well-formed asthi in human body. [Cha. Sa.[[Sharira Sthana]] 7/6].  
Sushruta opines the total number as 300. [Su.Sa Sharira Sthana  5/18]
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Sushruta opines the total number as 300. [Su.Sa. Sharira Sthana  5/18]
    
Currently, most sources state that there are total 270 bones in human body at the time of birth. Many bones fuse together and the count comes to 206 separate bones. This number does not include small sesamoid bones. <ref>Steele, D. Gentry; Claud A. Bramblett (1988). The Anatomy and Biology of the Human Skeleton. Texas A&M University Press. p. 4. ISBN 978-0-89096-300-5 Available from https://en.wikipedia.org/wiki/Bone#cite_note-1 cited on28/05/2020.</ref><ref>Mammal anatomy : an illustrated guide. New York: Marshall Cavendish. 2010. p. 129. ISBN 9780761478829. Available from https://en.wikipedia.org/wiki/Human_skeleton#cite_note-1 cited on 28/05/2020.</ref>
 
Currently, most sources state that there are total 270 bones in human body at the time of birth. Many bones fuse together and the count comes to 206 separate bones. This number does not include small sesamoid bones. <ref>Steele, D. Gentry; Claud A. Bramblett (1988). The Anatomy and Biology of the Human Skeleton. Texas A&M University Press. p. 4. ISBN 978-0-89096-300-5 Available from https://en.wikipedia.org/wiki/Bone#cite_note-1 cited on28/05/2020.</ref><ref>Mammal anatomy : an illustrated guide. New York: Marshall Cavendish. 2010. p. 129. ISBN 9780761478829. Available from https://en.wikipedia.org/wiki/Human_skeleton#cite_note-1 cited on 28/05/2020.</ref>
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=== Time span ===
 
=== Time span ===
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The asthi dhatu is formed on 5th day from the nutrient fluid (ahara rasa). [Cha.Sa. [[Chikitsa Sthana]] 15/20-21] However, Sushruta opines that the asthi dhatu is formed in a time span of 12060 kala (twenty days). [Su. Sa. Sutra Sthana 14/14]
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The asthi dhatu is formed on 5th day from the nutrient fluid (ahara rasa). [Cha.Sa. [[Chikitsa Sthana]] 15/20-21] However, Sushruta opines that the asthi dhatu is formed in a time span of 12060 kala (twenty days). [Su.Sa.Sutra Sthana 14/14]
    
== Characteristics of best quality or essence (asthisara) ==  
 
== Characteristics of best quality or essence (asthisara) ==  
600

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