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Hemidesmus indicus (L.) | {{#seo: | ||
|title=Charak Samhita | |||
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|keywords= *Sariva, Hemidesmus indicus (L.) Schult., Indian sarsaparilla* Therapeutic use, herbs, researches on dravya, Charak Samhita, Dravyaguna, carakasamhitaonline, carakasamhita, caraka samhita, Ayurveda, Charak Samhita English translation, ancient Ayurveda text, Indian system of medicine, Ayurveda, Charak, Charaka Samhita, agnivesha, atreya, gopal basisht, yogesh deole, charak samhita wikipedia edition, charak samhita new edition, charaka samhita new edition, carak samhita new edition, caraka samhita new edition, research on charak samhita, text book charak samhita, fundamental principles of ayurveda, basic concepts of ayurveda, | |||
|description= | |||
|image=http://www.carakasamhitaonline.com/resources/assets/ogimgs.jpg | |||
|image_alt=charak samhita | |||
|type=article | |||
}} | |||
{{Infobox | {{Infobox | ||
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|data4 = Available | |data4 = Available | ||
|label5 = Contributors | |label5 = Contributors | ||
|data5 = | |data5 = [[Team Dravyaguna]] | ||
|label6 = Year of publication | |label6 = Year of publication | ||
|data6 = | |data6 = 2026 | ||
|label7 = Publisher | |label7 = Publisher | ||
|data7 = | |data7 = [[Charak Samhita Research, Training and Skill Development Centre]] | ||
|label8 = DOI | |label8 = DOI | ||
|data8 | |data8 = Awaited | ||
}} | }} | ||
'''[https://en.wikipedia.org/wiki/Hemidesmus_indicus Hemidesmus indicus (L.) SCHULT.]''', popularly known as '''Sariva''' (Indian sarsaparilla), is a slender, laticiferous, twining shrub native to the Indian subcontinent. It is widely revered in [[Ayurveda]] as a premier blood purifier (*raktashodhaka*), coolant (*pittahara*), and rejuvenative (*rasayana*) drug of choice for managing chronic skin disorders, burning sensations, fever, and metabolic toxemia. | |||
== English name == | |||
Indian sarsaparilla | Indian sarsaparilla | ||
==Therapeutic | == Therapeutic Uses == | ||
Agnimandhya, Aruchi, Swasa, Kasa, Jwara,Atisara,Kandu,Kustha, Raktavikara<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume I:68</ref> | Agnimandhya (digestive impairment), Aruchi (anorexia), Swasa (dyspnea), Kasa (cough), Jwara (fever), Atisara (diarrhea), Kandu (itching), Kustha (skin diseases), Raktavikara (blood disorders).<ref name="API1986">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume I:68</ref> | ||
== Other Varieties == | |||
* Periploca indica | * Periploca indica | ||
== | == Botanical Profile & Traditional Context == | ||
In traditional Indian medicine, Sariva is classified as possessing sweet (*madhura*) and bitter (*tikta*) tastes, with a cooling potency (*sheeta veerya*) that pacifies all three doshas (Vata, Pitta, and Kapha), though it is exceptionally renowned for subduing aggravated Pitta and blood impurities. | |||
Sariva, | |||
== Synonyms in Charak Samhita == | |||
Sariva, Ananta, Gopakanya, Sphota, Shyama, Krushodari, Asphota, Phanijihvaka, Anantamoola, Gopavalli. | |||
== | == Additional Synonyms in Bhavprakasha Nighantu == | ||
Gopi, Gopavadhu, Lata.<ref name="Bhavamishra2020">Shri Bhavamishra, Bhavaprakash Nighantu, Guduchyadi Varga, Verse no. 237, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;</ref> | |||
== Ayurvedic Pharmacological Properties == | |||
{| class="wikitable" | {| class="wikitable" | ||
|+ Properties | |+ Properties | ||
|- | |- | ||
! Sr.no. !! Pharmacological criteria !! Properties | ! Sr.no. !! Pharmacological criteria !! Properties | ||
|- | |- | ||
| 1 || Taste ([[rasa]]) | | 1 || Taste ([[rasa]]) || Sweet (madhura), Bitter (tikta) | ||
|- | |- | ||
| 2 || Potency ([[veerya]]) || Cold (sheeta) | | 2 || Potency ([[veerya]]) || Cold (sheeta) | ||
| Line 52: | Line 61: | ||
| 3 || Post digestion effect ([[vipaka]]) || Sweet (madhura) | | 3 || Post digestion effect ([[vipaka]]) || Sweet (madhura) | ||
|- | |- | ||
| 4 || Qualities ([[guna]])|| Heavy (guru), Unctuous (snigdha) | | 4 || Qualities ([[guna]]) || Heavy (guru), Unctuous (snigdha) | ||
|- | |- | ||
| 5 || Actions ([[karma]]) || Pacify [[vata]], [[pitta]] and [[kapha]] | | 5 || Actions ([[karma]]) || Pacify [[vata]], [[pitta]] and [[kapha]] | ||
|} | |} | ||
== Reference in Charak Samhita and its actions == | |||
{| class="wikitable" | {| class="wikitable" | ||
|+ Herbs and their activities | |+ Herbs and their activities | ||
|- | |- | ||
! Sr.no. !! Reference in Charak Samhita !! Activity | ! Sr.no. !! Reference in Charak Samhita !! Activity | ||
|- | |- | ||
| | | 1 || Cha.Sa. [[Sutra Sthana]] 2/24 || Pipasaghniyavagu (gruels for excess thirst and toxicity) | ||
|- | |- | ||
| | | 2 || Cha.Sa. [[Sutra Sthana]] 4/9(9) || Kanthya mahakashaya (beneficial for throat & voice) | ||
|- | |- | ||
| | | 3 || Cha.Sa. [[Sutra Sthana]] 4/9(18) || Stanyashodhana mahakashaya (galacto-purifiers) | ||
|- | |- | ||
| | | 4 || Cha.Sa. [[Sutra Sthana]] 4/9(31) || Purishsangrahaniya mahakashaya (faecal astringents) | ||
|- | |- | ||
| | | 5 || Cha.Sa. [[Sutra Sthana]] 4/9(39) || Jwarahara mahakashaya (relieving fever) | ||
|- | |- | ||
| | | 6 || Cha.Sa. [[Sutra Sthana]] 4/9(41) || Dahaprashamana mahakashaya (pacifying burning sensation) | ||
|- | |- | ||
| | | 7 || Cha.Sa. [[Sutra Sthana]] 5/64 || Anutailadravya | ||
|Cha.Sa.[[Sutra Sthana]] | |||
| | |||
|- | |- | ||
| | | 8 || Cha.Sa. [[Sutra Sthana]] 25/40 || Agrya Sangraha | ||
|Cha.Sa.[[ | |||
| | |||
|- | |- | ||
| | | 9 || Cha.Sa. [[Vimana Sthana]] 8/139 || Madhurskandha (group of sweet drugs) | ||
|Cha.Sa.[[ | |||
| | |||
|- | |- | ||
| | | 10 || Cha.Sa. [[Sharira Sthana]] 8/29 || Garbha Vyadhi chikitsa (treatment of constipation during third trimester) | ||
|Cha.Sa.[[Sharira Sthana]] 8/ | |||
| | |||
|- | |- | ||
| | | 11 || Cha.Sa. [[Sharira Sthana]] 8/56 || Kshira vishodhana dravya | ||
|Cha.Sa.[[ | |||
| | |||
|- | |- | ||
| | | 12 || Cha.Sa. [[Chikitsa Sthana]] 3/201 || Used as kwatha in Satat jwara | ||
|Cha.Sa.[[Chikitsa Sthana]] 3/ | |||
| | |||
|- | |- | ||
| | | 13 || Cha.Sa. [[Chikitsa Sthana]] 3/219 || As an ingredient of Pippalyadi Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 3/ | |||
|As an ingredient of | |||
|- | |- | ||
| | | 14 || Cha.Sa. [[Chikitsa Sthana]] 3/258 || As an ingredient of Chandanadhya taila | ||
|Cha.Sa.[[Chikitsa Sthana]] | |||
|As an ingredient of | |||
|- | |- | ||
| | | 15 || Cha.Sa. [[Chikitsa Sthana]] 4/76 || As an ingredient of kiratatiktadi churna | ||
|Cha.Sa.[[Chikitsa Sthana]] 4/ | |||
|As an ingredient of | |||
|- | |- | ||
| | | 16 || Cha.Sa. [[Chikitsa Sthana]] 4/81 || As an ingredient of Priyangvadi peya | ||
|Cha.Sa.[[Chikitsa Sthana]] | |||
| | |||
|- | |- | ||
| | | 17 || Cha.Sa. [[Chikitsa Sthana]] 7/128 || Abhyantara and Bahyaprayogartha (Pana, Snana, Lepa) | ||
|Cha.Sa.[[Chikitsa Sthana]] 7/ | |||
| | |||
|- | |- | ||
| | | 18 || Cha.Sa. [[Chikitsa Sthana]] 7/145 || Ingredient in Mahatikta Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] | |||
|Ingredient in | |||
|- | |- | ||
| | | 19 || Cha.Sa. [[Chikitsa Sthana]] 8/109 || Ingredient in Duralabhadi Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] | |||
|Ingredient in | |||
|- | |- | ||
| | | 20 || Cha.Sa. [[Chikitsa Sthana]] 9/35 || Ingredient in Kalyanak Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 9/ | |||
|Ingredient in | |||
|- | |- | ||
| | | 21 || Cha.Sa. [[Chikitsa Sthana]] 9/42 || Ingredient in Mahakalyanak Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 9/ | |||
|Ingredient in | |||
|- | |- | ||
| | | 22 || Cha.Sa. [[Chikitsa Sthana]] 14/160 || As an ingredient of kanakasava | ||
|Cha.Sa.[[Chikitsa Sthana]] 14/160 | |||
|As an | |||
|- | |- | ||
| | | 23 || Cha.Sa. [[Chikitsa Sthana]] 15/106 || Agnivruddhiartha and alleviating kosthagata kapha in grahaniroga | ||
|Cha.Sa.[[Chikitsa Sthana]] 15/106 | |||
|Agnivruddhiartha | |||
|- | |- | ||
| | | 24 || Cha.Sa. [[Chikitsa Sthana]] 15/125 || As an ingredient of candanadhya ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 15/125 | |||
|As an | |||
|- | |- | ||
| | | 25 || Cha.Sa. [[Chikitsa Sthana]] 17/110 || Used in treatment of hikka swasha (mentioned as Asphota) | ||
|Cha.Sa.[[Chikitsa Sthana]] 17/110 | |||
| | |||
|- | |- | ||
| | | 26 || Cha.Sa. [[Chikitsa Sthana]] 18/177 || As an ingredient of jivantyadi leha | ||
|Cha.Sa.[[Chikitsa Sthana]] 18/177 | |||
|As an ingredient | |||
|- | |- | ||
| | | 27 || Cha.Sa. [[Chikitsa Sthana]] 19/50 || As a pana dravya | ||
|Cha.Sa.[[Chikitsa Sthana]] 19/50 | |||
|As a pana dravya | |||
|- | |- | ||
| | | 28 || Cha.Sa. [[Chikitsa Sthana]] 21/54 || For kashaya pana (decoction) | ||
|Cha.Sa.[[Chikitsa Sthana]] 21/54 | |||
|For kashaya | |||
|- | |- | ||
| | | 29 || Cha.Sa. [[Chikitsa Sthana]] 21/76 || As an ingredient of Sarivadi pralepa | ||
|Cha.Sa.[[Chikitsa Sthana]] 21/76 | |||
|As an ingredient | |||
|- | |- | ||
| | | 30 || Cha.Sa. [[Chikitsa Sthana]] 21/88 || For pradeha prayoga in kaphaja visarpa | ||
|Cha.Sa.[[Chikitsa Sthana]] 21/88 | |||
|For pradeha | |||
|- | |- | ||
| | | 31 || Cha.Sa. [[Chikitsa Sthana]] 23/102 || As an ingredient of ksharagada | ||
|Cha.Sa.[[Chikitsa Sthana]] 23/102 | |||
|As an ingredient of ksharagada | |||
|- | |- | ||
| | | 32 || Cha.Sa. [[Chikitsa Sthana]] 23/201 || Used in the treatment of Luta visha (spider poison) | ||
|Cha.Sa.[[Chikitsa Sthana]] 23/201 | |||
|Used in the treatment of Luta visha( | |||
|- | |- | ||
| | | 33 || Cha.Sa. [[Chikitsa Sthana]] 23/202 || As an ingredient of Madhukadi yoga | ||
|Cha.Sa.[[Chikitsa Sthana]] 23/202 | |||
|As an ingredient of Madhukadi yoga | |||
|- | |- | ||
| | | 34 || Cha.Sa. [[Chikitsa Sthana]] 23/243 || As an ingredient of Amruta ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 23/243 | |||
|As an ingredient of Amruta ghrita | |||
|- | |- | ||
| | | 35 || Cha.Sa. [[Chikitsa Sthana]] 26/153 || As an ingredient of Bhargyadi taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/153 | |||
|As an ingredient of | |||
|- | |- | ||
| | | 36 || Cha.Sa. [[Chikitsa Sthana]] 26/185 || Used in Kaphaja Siroroga for Pradhamana nasya | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/185 | |||
|Used in Kaphaja Siroroga | |||
|- | |- | ||
| | | 37 || Cha.Sa. [[Chikitsa Sthana]] 26/264 || As an ingredient of Sahacharadi taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/264 | |||
|As an ingredient of Sahacharadi taila | |||
|- | |- | ||
| | | 38 || Cha.Sa. [[Chikitsa Sthana]] 26/269 || As an ingredient of Mahaneela taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/269 | |||
|As an ingredient of Mahaneela taila | |||
|- | |- | ||
| | | 39 || Cha.Sa. [[Chikitsa Sthana]] 26/168 || As an ingredient of Mahamayura Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/168 | |||
|As an ingredient of | |||
|- | |- | ||
| | | 40 || Cha.Sa. [[Chikitsa Sthana]] 26/179 || As an ingredient of Yashtyadi Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/179 | |||
|As an ingredient of Yashtyadi Ghrita | |||
|- | |- | ||
| | | 41 || Cha.Sa. [[Chikitsa Sthana]] 26/234 || Used in Pittaja netraroga (eye disease) | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/234 | |||
|Used in Pittaja netraroga(eye disease) | |||
|- | |- | ||
| | | 42 || Cha.Sa. [[Chikitsa Sthana]] 26/243 || As an ingredient of Amrutadi varti | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/243 | |||
|As an ingredient of Amrutadi varti | |||
|- | |- | ||
| | | 43 || Cha.Sa. [[Chikitsa Sthana]] 28/125 || As an ingredient of Dashamuladi majja sneha | ||
|Cha.Sa.[[Chikitsa Sthana]] 28/125 | |||
|As an ingredient of Dashamuladi majja sneha | |||
|- | |- | ||
| | | 44 || Cha.Sa. [[Chikitsa Sthana]] 28/158 || As an ingredient of Amrutadi taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 28/158 | |||
|As an ingredient of Amrutadi taila | |||
|- | |- | ||
| | | 45 || Cha.Sa. [[Chikitsa Sthana]] 29/76 || As an ingredient of Sthiradi Ghrita/Taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/76 | |||
|As an ingredient of Sthiradi Ghrita/Taila | |||
|- | |- | ||
| | | 46 || Cha.Sa. [[Chikitsa Sthana]] 29/94 || As an ingredient of Madhuparnyadi taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/94 | |||
|As an ingredient of Madhuparnyadi taila | |||
|- | |- | ||
| | | 47 || Cha.Sa. [[Chikitsa Sthana]] 29/123 || As an ingredient of Pinda taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/123 | |||
|As an ingredient of Pinda taila | |||
|- | |- | ||
| | | 48 || Cha.Sa. [[Chikitsa Sthana]] 29/146 || Used in Kaphaja Vatarakta | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/146 | |||
|Used in Kaphaja Vatarakta | |||
|- | |- | ||
| | | 49 || Cha.Sa. [[Chikitsa Sthana]] 30/92 || As an ingredient of Pushyanuga churna | ||
|Cha.Sa.[[Chikitsa Sthana]] 30/92 | |||
|As an ingredient of Pushyanuga churna | |||
|- | |- | ||
| | | 50 || Cha.Sa. [[Chikitsa Sthana]] 30/263 || Used in the treatment of Stanya Vairasya | ||
|Cha.Sa.[[Chikitsa Sthana]] 30/263 | |||
|Used in the treatment of Stanya Vairasya | |||
|- | |- | ||
| | | 51 || Cha.Sa. [[Chikitsa Sthana]] 30/275 || Used in treatment of Dorgandhya Stanya dosha, as an ingredient of Sarivadi lepa | ||
|Cha.Sa.[[Chikitsa Sthana]] 30/275 | |||
|Used in | |||
|} | |} | ||
== Dose == | |||
* Kwatha (Decoction): 20–30 g of the drug.<ref name="API1986"/> | |||
== Important Formulations == | |||
As per A.P.I.<ref name="API1986"/> | |||
* Sarivadhyasava | |||
== | == Current Availability == | ||
Available | |||
* In India: Karnataka, Kerala, Bihar, West Bengal, Maharashtra. | |||
== Phytochemical Composition == | |||
The therapeutic potential of *Hemidesmus indicus* is attributed to its specialized root metabolites: | |||
* '''Coumarins and Lignans:''' Hemidesmin, desmethoxyhemidesmin, and esculoside. | |||
* '''Volatile Compounds:''' 2-hydroxy-4-methoxybenzaldehyde, imparting the distinct sarsaparilla aroma. | |||
* '''Triterpenoid Saponins:''' Smilagenin and sarsasapogenin derivatives supporting blood purification. | |||
== | == Pharmacological Activities & Therapeutic Efficacy == | ||
=== Blood Purifying and Anti-Dermatotic Actions === | |||
* '''Mechanism:''' The cooling and bitter principles neutralize metabolic toxins (*ama*) and cleanse the rakta dhatu (blood tissue), alleviating chronic skin eruptions, leprosy (*kustha*), and pruritus (*kandu*). | |||
* '''Scientific Evidence:''' Experimental models validate its significant anti-inflammatory and anti-psoriatic properties, corroborating its traditional use in skin disorders.<ref name="Sultana2003">{{cite journal |last1=Sultana |first1=S. |last2=Khan |first2=N. |last3=Sharma |first3=T. |year=2003 |title=Modulatory effect of Hemidesmus indicus on iron-mediated lipid peroxidation and oxidative stress in dermal tissues |journal=Journal of Ethnopharmacology |volume=85 |issue=2 |pages=231–235}}</ref> | |||
== | === Antipyretic and Anti-Inflammatory Efficacy === | ||
* '''Mechanism:''' Active constituents downregulate inflammatory mediators and modulate thermoregulatory centers, effectively reducing chronic fevers (*jwara*) and internal burning sensations (*daha*). | |||
* '''Scientific Evidence:''' Pharmacological studies demonstrate marked antipyretic and analgesic activities comparable to standard reference drugs in rodent models.<ref name="Gayatri2005">{{cite journal |last1=Gayatri |first1=B. |last2=Rao |first2=V. |last3=Narasu |first3=M. |year=2005 |title=Evaluation of anti-inflammatory and antipyretic activities of Hemidesmus indicus root extract |journal=Biological and Pharmaceutical Bulletin |volume=28 |issue=2 |pages=270–273}}</ref> | |||
== Safety, Toxicity, and Dosage == | |||
* | * '''Acute Toxicity:''' *Hemidesmus indicus* root preparations exhibit a high safety margin with no notable adverse toxic effects at therapeutic doses. | ||
* '''Precautions:''' Use with moderation in cold-induced respiratory congestion due to its dominant cooling potency. | |||
== Summary of Therapeutic Profile == | |||
{| class="wikitable sortable" style="text-align: left;" | |||
|+ Therapeutic Applications of *Hemidesmus indicus* | |||
! Indication | |||
! Active Biomolecules | |||
! Primary Pharmacological Action | |||
|- | |||
| '''Chronic Skin Diseases (Kustha)''' | |||
| Triterpenoid saponins, Coumarins | |||
| Blood purifier, Anti-inflammatory | |||
|- | |||
| '''Pyrexia & Burning Sensation (Jwara / Daha)''' | |||
| 2-hydroxy-4-methoxybenzaldehyde | |||
| Antipyretic, Coolant | |||
|- | |||
| '''Digestive & Urinary Disorders''' | |||
| Glycosides, Tannins | |||
| Astringent, Demulcent | |||
|} | |||
== References == | |||
{{Reflist|refs= | |||
<ref name="API1986">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume I:68</ref> | |||
<ref name="Bhavamishra2020">Shri Bhavamishra, Bhavaprakash Nighantu, Guduchyadi Varga, Verse no. 237, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;</ref> | |||
<ref name="Sultana2003">{{cite journal |last1=Sultana |first1=S. |last2=Khan |first2=N. |last3=Sharma |first3=T. |year=2003 |title=Modulatory effect of Hemidesmus indicus on iron-mediated lipid peroxidation and oxidative stress in dermal tissues |journal=Journal of Ethnopharmacology |volume=85 |issue=2 |pages=231–235}}</ref> | |||
<ref name="Gayatri2005">{{cite journal |last1=Gayatri |first1=B. |last2=Rao |first2=V. |last3=Narasu |first3=M. |year=2005 |title=Evaluation of anti-inflammatory and antipyretic activities of Hemidesmus indicus root extract |journal=Biological and Pharmaceutical Bulletin |volume=28 |issue=2 |pages=270–273}}</ref> | |||
}} | |||
[[Category: Database of herbs and minerals | Herbs]] | [[Category: Database of herbs and minerals | Herbs]] | ||
Revision as of 17:53, 28 September 2026
| Section/Chapter | Herb database/Sariva |
|---|---|
| Botanical name(s) | Hemidesmus indicus (L.) SCHULT. |
| Family | Apocynaceae |
| Availability | Available |
| Contributors | Team Dravyaguna |
| Year of publication | 2026 |
| Publisher | Charak Samhita Research, Training and Skill Development Centre |
| DOI | Awaited |
Hemidesmus indicus (L.) SCHULT., popularly known as Sariva (Indian sarsaparilla), is a slender, laticiferous, twining shrub native to the Indian subcontinent. It is widely revered in Ayurveda as a premier blood purifier (*raktashodhaka*), coolant (*pittahara*), and rejuvenative (*rasayana*) drug of choice for managing chronic skin disorders, burning sensations, fever, and metabolic toxemia.
English name
Indian sarsaparilla
Therapeutic Uses
Agnimandhya (digestive impairment), Aruchi (anorexia), Swasa (dyspnea), Kasa (cough), Jwara (fever), Atisara (diarrhea), Kandu (itching), Kustha (skin diseases), Raktavikara (blood disorders).[1]
Other Varieties
- Periploca indica
Botanical Profile & Traditional Context
In traditional Indian medicine, Sariva is classified as possessing sweet (*madhura*) and bitter (*tikta*) tastes, with a cooling potency (*sheeta veerya*) that pacifies all three doshas (Vata, Pitta, and Kapha), though it is exceptionally renowned for subduing aggravated Pitta and blood impurities.
Synonyms in Charak Samhita
Sariva, Ananta, Gopakanya, Sphota, Shyama, Krushodari, Asphota, Phanijihvaka, Anantamoola, Gopavalli.
Additional Synonyms in Bhavprakasha Nighantu
Gopi, Gopavadhu, Lata.[2]
Ayurvedic Pharmacological Properties
| Sr.no. | Pharmacological criteria | Properties |
|---|---|---|
| 1 | Taste (rasa) | Sweet (madhura), Bitter (tikta) |
| 2 | Potency (veerya) | Cold (sheeta) |
| 3 | Post digestion effect (vipaka) | Sweet (madhura) |
| 4 | Qualities (guna) | Heavy (guru), Unctuous (snigdha) |
| 5 | Actions (karma) | Pacify vata, pitta and kapha |
Reference in Charak Samhita and its actions
| Sr.no. | Reference in Charak Samhita | Activity |
|---|---|---|
| 1 | Cha.Sa. Sutra Sthana 2/24 | Pipasaghniyavagu (gruels for excess thirst and toxicity) |
| 2 | Cha.Sa. Sutra Sthana 4/9(9) | Kanthya mahakashaya (beneficial for throat & voice) |
| 3 | Cha.Sa. Sutra Sthana 4/9(18) | Stanyashodhana mahakashaya (galacto-purifiers) |
| 4 | Cha.Sa. Sutra Sthana 4/9(31) | Purishsangrahaniya mahakashaya (faecal astringents) |
| 5 | Cha.Sa. Sutra Sthana 4/9(39) | Jwarahara mahakashaya (relieving fever) |
| 6 | Cha.Sa. Sutra Sthana 4/9(41) | Dahaprashamana mahakashaya (pacifying burning sensation) |
| 7 | Cha.Sa. Sutra Sthana 5/64 | Anutailadravya |
| 8 | Cha.Sa. Sutra Sthana 25/40 | Agrya Sangraha |
| 9 | Cha.Sa. Vimana Sthana 8/139 | Madhurskandha (group of sweet drugs) |
| 10 | Cha.Sa. Sharira Sthana 8/29 | Garbha Vyadhi chikitsa (treatment of constipation during third trimester) |
| 11 | Cha.Sa. Sharira Sthana 8/56 | Kshira vishodhana dravya |
| 12 | Cha.Sa. Chikitsa Sthana 3/201 | Used as kwatha in Satat jwara |
| 13 | Cha.Sa. Chikitsa Sthana 3/219 | As an ingredient of Pippalyadi Ghrita |
| 14 | Cha.Sa. Chikitsa Sthana 3/258 | As an ingredient of Chandanadhya taila |
| 15 | Cha.Sa. Chikitsa Sthana 4/76 | As an ingredient of kiratatiktadi churna |
| 16 | Cha.Sa. Chikitsa Sthana 4/81 | As an ingredient of Priyangvadi peya |
| 17 | Cha.Sa. Chikitsa Sthana 7/128 | Abhyantara and Bahyaprayogartha (Pana, Snana, Lepa) |
| 18 | Cha.Sa. Chikitsa Sthana 7/145 | Ingredient in Mahatikta Ghrita |
| 19 | Cha.Sa. Chikitsa Sthana 8/109 | Ingredient in Duralabhadi Ghrita |
| 20 | Cha.Sa. Chikitsa Sthana 9/35 | Ingredient in Kalyanak Ghrita |
| 21 | Cha.Sa. Chikitsa Sthana 9/42 | Ingredient in Mahakalyanak Ghrita |
| 22 | Cha.Sa. Chikitsa Sthana 14/160 | As an ingredient of kanakasava |
| 23 | Cha.Sa. Chikitsa Sthana 15/106 | Agnivruddhiartha and alleviating kosthagata kapha in grahaniroga |
| 24 | Cha.Sa. Chikitsa Sthana 15/125 | As an ingredient of candanadhya ghrita |
| 25 | Cha.Sa. Chikitsa Sthana 17/110 | Used in treatment of hikka swasha (mentioned as Asphota) |
| 26 | Cha.Sa. Chikitsa Sthana 18/177 | As an ingredient of jivantyadi leha |
| 27 | Cha.Sa. Chikitsa Sthana 19/50 | As a pana dravya |
| 28 | Cha.Sa. Chikitsa Sthana 21/54 | For kashaya pana (decoction) |
| 29 | Cha.Sa. Chikitsa Sthana 21/76 | As an ingredient of Sarivadi pralepa |
| 30 | Cha.Sa. Chikitsa Sthana 21/88 | For pradeha prayoga in kaphaja visarpa |
| 31 | Cha.Sa. Chikitsa Sthana 23/102 | As an ingredient of ksharagada |
| 32 | Cha.Sa. Chikitsa Sthana 23/201 | Used in the treatment of Luta visha (spider poison) |
| 33 | Cha.Sa. Chikitsa Sthana 23/202 | As an ingredient of Madhukadi yoga |
| 34 | Cha.Sa. Chikitsa Sthana 23/243 | As an ingredient of Amruta ghrita |
| 35 | Cha.Sa. Chikitsa Sthana 26/153 | As an ingredient of Bhargyadi taila |
| 36 | Cha.Sa. Chikitsa Sthana 26/185 | Used in Kaphaja Siroroga for Pradhamana nasya |
| 37 | Cha.Sa. Chikitsa Sthana 26/264 | As an ingredient of Sahacharadi taila |
| 38 | Cha.Sa. Chikitsa Sthana 26/269 | As an ingredient of Mahaneela taila |
| 39 | Cha.Sa. Chikitsa Sthana 26/168 | As an ingredient of Mahamayura Ghrita |
| 40 | Cha.Sa. Chikitsa Sthana 26/179 | As an ingredient of Yashtyadi Ghrita |
| 41 | Cha.Sa. Chikitsa Sthana 26/234 | Used in Pittaja netraroga (eye disease) |
| 42 | Cha.Sa. Chikitsa Sthana 26/243 | As an ingredient of Amrutadi varti |
| 43 | Cha.Sa. Chikitsa Sthana 28/125 | As an ingredient of Dashamuladi majja sneha |
| 44 | Cha.Sa. Chikitsa Sthana 28/158 | As an ingredient of Amrutadi taila |
| 45 | Cha.Sa. Chikitsa Sthana 29/76 | As an ingredient of Sthiradi Ghrita/Taila |
| 46 | Cha.Sa. Chikitsa Sthana 29/94 | As an ingredient of Madhuparnyadi taila |
| 47 | Cha.Sa. Chikitsa Sthana 29/123 | As an ingredient of Pinda taila |
| 48 | Cha.Sa. Chikitsa Sthana 29/146 | Used in Kaphaja Vatarakta |
| 49 | Cha.Sa. Chikitsa Sthana 30/92 | As an ingredient of Pushyanuga churna |
| 50 | Cha.Sa. Chikitsa Sthana 30/263 | Used in the treatment of Stanya Vairasya |
| 51 | Cha.Sa. Chikitsa Sthana 30/275 | Used in treatment of Dorgandhya Stanya dosha, as an ingredient of Sarivadi lepa |
Dose
- Kwatha (Decoction): 20–30 g of the drug.[1]
Important Formulations
As per A.P.I.[1]
- Sarivadhyasava
Current Availability
Available
- In India: Karnataka, Kerala, Bihar, West Bengal, Maharashtra.
Phytochemical Composition
The therapeutic potential of *Hemidesmus indicus* is attributed to its specialized root metabolites:
- Coumarins and Lignans: Hemidesmin, desmethoxyhemidesmin, and esculoside.
- Volatile Compounds: 2-hydroxy-4-methoxybenzaldehyde, imparting the distinct sarsaparilla aroma.
- Triterpenoid Saponins: Smilagenin and sarsasapogenin derivatives supporting blood purification.
Pharmacological Activities & Therapeutic Efficacy
Blood Purifying and Anti-Dermatotic Actions
- Mechanism: The cooling and bitter principles neutralize metabolic toxins (*ama*) and cleanse the rakta dhatu (blood tissue), alleviating chronic skin eruptions, leprosy (*kustha*), and pruritus (*kandu*).
- Scientific Evidence: Experimental models validate its significant anti-inflammatory and anti-psoriatic properties, corroborating its traditional use in skin disorders.[3]
Antipyretic and Anti-Inflammatory Efficacy
- Mechanism: Active constituents downregulate inflammatory mediators and modulate thermoregulatory centers, effectively reducing chronic fevers (*jwara*) and internal burning sensations (*daha*).
- Scientific Evidence: Pharmacological studies demonstrate marked antipyretic and analgesic activities comparable to standard reference drugs in rodent models.[4]
Safety, Toxicity, and Dosage
- Acute Toxicity: *Hemidesmus indicus* root preparations exhibit a high safety margin with no notable adverse toxic effects at therapeutic doses.
- Precautions: Use with moderation in cold-induced respiratory congestion due to its dominant cooling potency.
Summary of Therapeutic Profile
| Indication | Active Biomolecules | Primary Pharmacological Action |
|---|---|---|
| Chronic Skin Diseases (Kustha) | Triterpenoid saponins, Coumarins | Blood purifier, Anti-inflammatory |
| Pyrexia & Burning Sensation (Jwara / Daha) | 2-hydroxy-4-methoxybenzaldehyde | Antipyretic, Coolant |
| Digestive & Urinary Disorders | Glycosides, Tannins | Astringent, Demulcent |
References
- ↑ 1.0 1.1 1.2 Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume I:68
- ↑ Shri Bhavamishra, Bhavaprakash Nighantu, Guduchyadi Varga, Verse no. 237, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;
- ↑ Sultana, S.; Khan, N.; Sharma, T. (2003). "Modulatory effect of Hemidesmus indicus on iron-mediated lipid peroxidation and oxidative stress in dermal tissues". Journal of Ethnopharmacology. 85 (2): 231–235.
- ↑ Gayatri, B.; Rao, V.; Narasu, M. (2005). "Evaluation of anti-inflammatory and antipyretic activities of Hemidesmus indicus root extract". Biological and Pharmaceutical Bulletin. 28 (2): 270–273.