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Aquilaria | {{#seo: | ||
|title=Charak Samhita - Herb Database | |||
|titlemode=append | |||
|keywords=Aguru, Aquilaria agallocha, Eaglewood, Agarwood, Aloeswood, Shwasahara, Charak Samhita, Dravyaguna, Ayurvedic pharmacopoeia, Anu taila, Chyavanprasha, Essential oil,Therapeutic use, herbs, researches on dravya, Charak Samhita, Dravyaguna, carakasamhitaonline, carakasamhita, caraka samhita, Ayurveda, Charak Samhita English translation, ancient Ayurveda text, Indian system of medicine, Ayurveda, Charak, Charaka Samhita, agnivesha, atreya, gopal basisht, yogesh deole, charak samhita wikipedia edition, charak samhita new edition, charaka samhita new edition, carak samhita new edition, caraka samhita new edition, research on charak samhita, text book charak samhita, fundamental principles of ayurveda, basic concepts of ayurveda | |||
|description=Monograph on Aguru (Aquilaria agallocha Roxb.): comprehensive botanical profile, classical Ayurvedic pharmacodynamics, phytochemical constituents, and evidence-based therapeutic efficacy. | |||
|image=http://www.carakasamhitaonline.com/resources/assets/ogimgs.jpg | |||
|image_alt=Aguru - Aquilaria agallocha | |||
|type=article | |||
}} | |||
{{Infobox | {{Infobox | ||
|title = Aguru | |title = Aguru | ||
|label1 = Section/Chapter | |label1 = Section/Chapter | ||
|data1 = Herb database/ | |data1 = Herb database/aguru | ||
|label2 = Botanical name(s) | |label2 = Botanical name(s) | ||
|data2 = Aquilaria malaccensis | |data2 = Aquilaria agallocha Roxb. (syn. Aquilaria malaccensis Lam.) | ||
|label3 = | |label3 = Family | ||
|data3 = | |data3 = Thymelaeaceae | ||
|label4 = Year of publication | |label4 = Availability | ||
| | |data4 = Available | ||
| | |label5 = Contributors | ||
| | |data5 = [[Team Dravyaguna]] | ||
| | |label6 = Year of publication | ||
| | |data6 = 2026 | ||
|label7 = Publisher | |||
|data7 = [[Charak Samhita Research, Training and Skill Development Centre]] | |||
|label8 = DOI | |||
|data8 = {{DoiWithLink}} | |||
}} | }} | ||
[[File:Aguru.jpg|thumb|'''Aguru (''Aquilaria agallocha'')''']] | |||
'''Aguru''' (Latin: ''Aquilaria agallocha'' Roxb., syn. ''Aquilaria malaccensis'' Lam.; family: Thymelaeaceae) is a large evergreen tree native to the northeastern regions of India, Bhutan, and parts of Southeast Asia. In [[Ayurveda]], the invaluable aromatic heartwood (Agarwood) is historically formed as a pathological defense response following fungal infection, revered for its penetrating, warming potency and powerful therapeutic efficacy in managing respiratory distress, skin disorders, and neurological imbalances.<ref name="API">{{cite book |title=The Ayurvedic Pharmacopoeia of India |year=1986 |publisher=Department of Ayush, Ministry of Health and Family Welfare, Govt. of India |volume=4 |pages=02 |edition=Part I}}</ref> | |||
== | == Botanical & Vernacular Names == | ||
* '''Botanical Name:''' ''Aquilaria agallocha'' Roxb. (syn. ''Aquilaria malaccensis'' Lam.) | |||
* '''Family:''' Thymelaeaceae | |||
* '''English Names:''' Eaglewood, Agarwood, Aloeswood | |||
* '''Sanskrit / Classical Names:''' ''Aguru'', ''Pravara'', ''Loha'', ''Rajarha'', ''Yogaja'', ''Vashik'', ''Krumija'' | |||
* '''Hindi:''' Agaru, Agar | |||
* '''Bengali:''' Agor, Agar | |||
* '''Assamese:''' Sasi, Agaru | |||
- | == Synonyms in Classical Texts == | ||
* '''Synonyms in Charak Samhita:''' | |||
** ''Aguru'' – Classical designation. | |||
** ''Pravara'' – Denotes its status as a potent and superior drug. | |||
** ''Loha'' – Refers to the heavy, dense resinous heartwood that sinks in water. | |||
** ''Rajarha'' – Valued and fit for royalty due to its exquisite fragrance. | |||
** ''Yogaja'' – Formulated or generated through internal changes/infestation. | |||
** ''Vashik'' – Possessing soothing and controlling attributes. | |||
** ''Krumija'' / ''Krumijagdha'' – Aromatic resin formed as a result of fungal infestation. | |||
* '''Synonyms in Bhavaprakasha Nighantu:'''<ref name="Bhavaprakash">{{cite book |last=Chunekar |first=Krushnachandra |title=Bhavaprakash Nighantu |year=2020 |publisher=Chaukhambha Bharati Academy |pages=Karpuradi varga, verse no.- 21, 22 |edition=Reprint}}</ref> | |||
** ''Anaaryaka'' – Plant commonly growing in the hilly regions of the northeastern parts of India. | |||
== | == Varieties == | ||
=== Raja Nighantu === | |||
Five varieties are mentioned:<ref name="RajaNighantu">{{cite book |last=Tripathi |first=Indradev |title=Raja Nighantu of Pandit Narhari |year=2006 |publisher=Chaukhambha Krishnadas Academy |location=Varanasi |pages=Chandanadi varga verse no- 85, 87, 89, 91, 92}}</ref> | |||
# Swadu | |||
# Krushna aguru | |||
# Kaastha aguru | |||
# Daaha aguru | |||
# Maangalya aguru | |||
== | == Ayurvedic Pharmacological Properties == | ||
According to classical Ayurvedic pharmacodynamics (''Rasa Panchaka''), Aguru possesses a hot potency and pungent-bitter taste profile, making it highly effective in pacifying Kapha and Vata doshas:<ref name="API" /> | |||
{| class="wikitable" | {| class="wikitable sortable" style="text-align:left;" | ||
! Sr. No. !! Pharmacological Criteria !! Properties (Ayurvedic Attributes) | |||
|- | |- | ||
| 1 || '''Taste (''[[Rasa]]'')''' || Bitter (''Tikta''), Pungent (''Katu'') | |||
|- | |- | ||
| | | 2 || '''Potency (''[[Veerya]]'')'''|| Hot (''Ushna'') | ||
|- | |- | ||
| | | 3 || '''Post-digestion Effect (''[[Vipaka]]'')'''|| Pungent (''Katu'') | ||
|- | |- | ||
| | | 4 || '''Qualities (''[[Guna]]'')'''|| Light (''Laghu''), Rough (''Ruksha''), Sharpness (''Tikshna'') | ||
|- | |- | ||
| 5 || '''Dosha Action (''[[Karma]]'')'''|| Pacifies Kapha and Vata (''Kapha-Vatahara'') | |||
|} | |} | ||
== | == References in Charak Samhita and its Actions == | ||
Aguru is prominently documented across multiple therapeutic chapters of the ''[[Charaka Samhita]]'': | |||
{| class="wikitable" | {| class="wikitable sortable" style="text-align:left;" | ||
| | ! Sr. No. !! Reference in Charak Samhita !! Activity / Formulation / Therapeutic Use | ||
|- | |||
| 1 || Cha.Sa.[[Sutra Sthana]] 4/9(37) || Shwasahara mahakashaya (relieving respiratory distress) | |||
|- | |||
| 2 || Cha.Sa.[[Sutra Sthana]] 4/9(42) || Sheetaprashamana mahakashaya (pacifying cold) | |||
|- | |||
| 3 || Cha.Sa.[[Sutra Sthana]] 5/21 || Dhuma varti dravya (ingredient of therapeutic inhalation for disease prevention) | |||
|- | |||
| 4 || Cha.Sa.[[Sutra Sthana]] 5/26 || Vairechanika dhuma varti (ingredient of smoke inhalation with unctuous substances) | |||
|- | |- | ||
| 5 || Cha.Sa.[[Sutra Sthana]] 5/63 || Anu taila dravya | |||
|- | |- | ||
| | | 6 || Cha.Sa.[[Sutra Sthana]] 6/16 || Vihara in Hemanta Rutu | ||
|- | |- | ||
| | | 7 || Cha.Sa.[[Sutra Sthana]] 6/25 || Vihara in Vasanta Rutu | ||
|- | |- | ||
| | | 8 || Cha.Sa.[[Sutra Sthana]] 25/40 || Agrya Sangraha (collections of best food articles, factors and drugs) | ||
|- | |- | ||
| | | 9 || Cha.Sa.[[Sutra Sthana]] 26/49 || Veerya varnan | ||
|- | |- | ||
| | | 10 || Cha.Sa.[[Vimana Sthana]] 8/143 || Tikta skandha (group of bitter drugs) | ||
|- | |- | ||
| 11 || Cha.Sa.[[Sharira Sthana]] 8/41 || Prajata stree paricharya / Apara patana (post-delivery management) | |||
|- | |||
| 12 || Cha.Sa.[[Chikitsa Sthana]] 6/28 || Used for decoction in ''Kaphaja prameha'' (diabetes) | |||
|- | |||
| 13 || Cha.Sa.[[Chikitsa Sthana]] 12/36 || Ingredient in Punarnavadhyarisht | |||
|- | |||
| 14 || Cha.Sa.[[Chikitsa Sthana]] 12/65 || For ''Lepa, Abhyangadi Bahyaprayogarth'' (external applications) | |||
|- | |||
| 15 || Cha.Sa.[[Chikitsa Sthana]] 12/70 || As a ''Lepa dravya'' in ''Kaphaj Shvayathu'' (swelling) | |||
|- | |||
| 16 || Cha.Sa.[[Chikitsa Sthana]] 15/148 || As an ingredient of Madhookasava | |||
|- | |||
| 17 || Cha.Sa.[[Chikitsa Sthana]] 15/163 || As an ingredient of Madhvarishta | |||
|- | |||
| 18 || Cha.Sa.[[Chikitsa Sthana]] 17/80 || Used for shodhanottara dhumapana | |||
|- | |||
| 19 || Cha.Sa.[[Chikitsa Sthana]] 17/123 || As an ingredient of shatyadi churna | |||
|- | |||
| 20 || Cha.Sa.[[Chikitsa Sthana]] 23/77 || As an ingredient of Mahagandha hasti agada | |||
|- | |||
| 21 || Cha.Sa.[[Chikitsa Sthana]] 23/231 || Used in the treatment of animals suffering with poison | |||
|- | |||
| 22 || Cha.Sa.[[Chikitsa Sthana]] 25/91 || As an ingredient of Kampillakadi taila | |||
|- | |||
| 23 || Cha.Sa.[[Chikitsa Sthana]] 26/182 || Used in Kaphaja sira shoola for dhoomavarti | |||
|- | |||
| 24 || Cha.Sa.[[Chikitsa Sthana]] 26/188 || As an ingredient of Pippalyadi churna for kavala karma (gargling) | |||
|- | |||
| 25 || Cha.Sa.[[Chikitsa Sthana]] 26/209 || As an ingredient of Khadiradi gutika | |||
|- | |||
| 26 || Cha.Sa.[[Chikitsa Sthana]] 26/270 || As an ingredient of Mahaneela taila | |||
|- | |||
| 27 || Cha.Sa.[[Chikitsa Sthana]] 27/41 || As an ingredient of Piluparnyadi Yoga | |||
|- | |||
| 28 || Cha.Sa.[[Chikitsa Sthana]] 27/54 || As an ingredient of Vatsakadi Pralepa (external application) | |||
|- | |||
| 29 || Cha.Sa.[[Chikitsa Sthana]] 28/150 || As an ingredient of Bala taila | |||
|- | |||
| 30 || Cha.Sa.[[Chikitsa Sthana]] 28/168 || As an ingredient of Mulakadhya taila | |||
|- | |||
| 31 || Cha.Sa.[[Chikitsa Sthana]] 28/179 || Agurvadi taila is useful in Vata vyadhi | |||
|- | |||
| 32 || Cha.Sa.[[Chikitsa Sthana]] 29/92 || As an ingredient of Madhuparnyadi taila | |||
|- | |||
| 33 || Cha.Sa.[[Chikitsa Sthana]] 29/107 || As an ingredient of Amrutadya taila | |||
|- | |||
| 34 || Cha.Sa.[[Kalpa Sthana]] 1/23 || Vamanarth (for emesis) | |||
|- | |||
| 35 || Cha.Sa.[[Chikitsa Sthana]] 1/1/58 || In formulation of dwitiya brahma rasayana | |||
|- | |||
| 36 || Cha.Sa.[[Chikitsa Sthana]] 2/3/28 || As a mood enhancer | |||
|} | |} | ||
== | == Therapeutic Indications (Classical) == | ||
Aguru is traditionally indicated in the clinical management of:<ref name="API" /> | |||
* ''Akshiroga'' (Eye diseases) | |||
* ''Shwasa'' (Dyspnea / Respiratory distress) | |||
* ''Karna roga'' (Ear diseases) | |||
* ''Kushtha'' (Dermatological disorders / Skin diseases) | |||
* ''Visha'' (Toxic conditions / Poisoning) | |||
Available | == Dosage & Administration == | ||
* '''Powder (''Churna''):''' 1 – 3 g daily in divided doses.<ref name="API" /> | |||
== Classical Formulations == | |||
* ''Madhukasava'' | |||
* ''Mrudvikasava'' | |||
* ''Karpuradyarka'' | |||
* ''Chyavanprasha avaleha'' | |||
* ''Anu taila'' | |||
* ''Chandanadi taila'' | |||
* ''Khadiradi gutika'' | |||
* ''Swasahara kashaya churna'' | |||
* ''Guduchyadi taila'' | |||
== Current Researches == | |||
=== Phytochemical Composition === | |||
Modern phytochemical profiling of ''Aquilaria agallocha'' resinous heartwood reveals a dense matrix of active constituents: | |||
* '''Sesquiterpenes:''' Alpha-guaiene, beta-elemene, agarospirol, valencene, and jinkoh-eremol. | |||
* '''Chromones:''' 2-(2-phenylethyl)chromone derivatives and flindersia-type chromones imparting stability and aroma. | |||
* '''Phenolic Compounds & Flavonoids:''' Luteolin, genkwanin, and diverse benzophenone derivatives exhibiting strong antioxidant properties. | |||
=== Pharmacological Activities & Therapeutic Efficacy === | |||
* '''Anti-Inflammatory & Analgesic Efficacy:''' Sesquiterpenes and chromones inhibit lipoxygenase and cyclooxygenase pathways, suppressing inflammatory mediators.<ref name="ResearchAPI">{{cite journal |title=Pharmacological evaluation and phytochemical constituents of Aquilaria agallocha |journal=Journal of Ethnopharmacology |year=2021}}</ref> | |||
* '''Neuroprotective & Anxiolytic Actions:''' Volatile sesquiterpenes cross the blood-brain barrier, interacting positively with GABAergic receptor systems to moderate central nervous system excitability.<ref name="ResearchAPI" /> | |||
* '''Antimicrobial & Antioxidant Properties:''' Phenolic fractions and oxygenated sesquiterpenes disrupt microbial membrane integrity while scavenging reactive oxygen species (ROS), validating its efficacy against skin pathogens.<ref name="ResearchAPI" /> | |||
== Current Availability == | |||
* Available in India, particularly in the Himalayan region, Assam, and Manipur. | |||
== References == | |||
{{Reflist|refs= | |||
<ref name="API">{{cite book |title=The Ayurvedic Pharmacopoeia of India |year=1986 |publisher=Department of Ayush, Ministry of Health and Family Welfare, Govt. of India |volume=4 |pages=02 |edition=Part I}}</ref> | |||
<ref name="Bhavaprakash">{{cite book |last=Chunekar |first=Krushnachandra |title=Bhavaprakash Nighantu |year=2020 |publisher=Chaukhambha Bharati Academy |pages=Karpuradi varga, verse no.- 21, 22 |edition=Reprint}}</ref> | |||
<ref name="RajaNighantu">{{cite book |last=Tripathi |first=Indradev |title=Raja Nighantu of Pandit Narhari |year=2006 |publisher=Chaukhambha Krishnadas Academy |location=Varanasi |pages=Chandanadi varga verse no- 85, 87, 89, 91, 92}}</ref> | |||
<ref name="ResearchAPI">{{cite journal |title=Pharmacological evaluation and phytochemical constituents of Aquilaria agallocha |journal=Journal of Ethnopharmacology |year=2021}}</ref> | |||
}} | |||
== External links == | |||
[https://cb.imsc.res.in/imppat/phytochemical/Aquilaria%20agallocha IMPPAT Database] | |||
[ | [https://en.wikipedia.org/wiki/Agarwood Wikipedia] | ||
[[index.php?title=Category:Database of herbs and minerals| Herbs]] | |||
Latest revision as of 06:15, 23 September 2026
| Section/Chapter | Herb database/aguru |
|---|---|
| Botanical name(s) | Aquilaria agallocha Roxb. (syn. Aquilaria malaccensis Lam.) |
| Family | Thymelaeaceae |
| Availability | Available |
| Contributors | Team Dravyaguna |
| Year of publication | 2026 |
| Publisher | Charak Samhita Research, Training and Skill Development Centre |
| DOI | 10.47468/CSNE.2026.e01.s10.33 |

Aguru (Latin: Aquilaria agallocha Roxb., syn. Aquilaria malaccensis Lam.; family: Thymelaeaceae) is a large evergreen tree native to the northeastern regions of India, Bhutan, and parts of Southeast Asia. In Ayurveda, the invaluable aromatic heartwood (Agarwood) is historically formed as a pathological defense response following fungal infection, revered for its penetrating, warming potency and powerful therapeutic efficacy in managing respiratory distress, skin disorders, and neurological imbalances.[1]
Botanical & Vernacular Names
- Botanical Name: Aquilaria agallocha Roxb. (syn. Aquilaria malaccensis Lam.)
- Family: Thymelaeaceae
- English Names: Eaglewood, Agarwood, Aloeswood
- Sanskrit / Classical Names: Aguru, Pravara, Loha, Rajarha, Yogaja, Vashik, Krumija
- Hindi: Agaru, Agar
- Bengali: Agor, Agar
- Assamese: Sasi, Agaru
Synonyms in Classical Texts
- Synonyms in Charak Samhita:
- Aguru – Classical designation.
- Pravara – Denotes its status as a potent and superior drug.
- Loha – Refers to the heavy, dense resinous heartwood that sinks in water.
- Rajarha – Valued and fit for royalty due to its exquisite fragrance.
- Yogaja – Formulated or generated through internal changes/infestation.
- Vashik – Possessing soothing and controlling attributes.
- Krumija / Krumijagdha – Aromatic resin formed as a result of fungal infestation.
- Synonyms in Bhavaprakasha Nighantu:[2]
- Anaaryaka – Plant commonly growing in the hilly regions of the northeastern parts of India.
Varieties
Raja Nighantu
Five varieties are mentioned:[3]
- Swadu
- Krushna aguru
- Kaastha aguru
- Daaha aguru
- Maangalya aguru
Ayurvedic Pharmacological Properties
According to classical Ayurvedic pharmacodynamics (Rasa Panchaka), Aguru possesses a hot potency and pungent-bitter taste profile, making it highly effective in pacifying Kapha and Vata doshas:[1]
| Sr. No. | Pharmacological Criteria | Properties (Ayurvedic Attributes) |
|---|---|---|
| 1 | Taste (Rasa) | Bitter (Tikta), Pungent (Katu) |
| 2 | Potency (Veerya) | Hot (Ushna) |
| 3 | Post-digestion Effect (Vipaka) | Pungent (Katu) |
| 4 | Qualities (Guna) | Light (Laghu), Rough (Ruksha), Sharpness (Tikshna) |
| 5 | Dosha Action (Karma) | Pacifies Kapha and Vata (Kapha-Vatahara) |
References in Charak Samhita and its Actions
Aguru is prominently documented across multiple therapeutic chapters of the Charaka Samhita:
| Sr. No. | Reference in Charak Samhita | Activity / Formulation / Therapeutic Use |
|---|---|---|
| 1 | Cha.Sa.Sutra Sthana 4/9(37) | Shwasahara mahakashaya (relieving respiratory distress) |
| 2 | Cha.Sa.Sutra Sthana 4/9(42) | Sheetaprashamana mahakashaya (pacifying cold) |
| 3 | Cha.Sa.Sutra Sthana 5/21 | Dhuma varti dravya (ingredient of therapeutic inhalation for disease prevention) |
| 4 | Cha.Sa.Sutra Sthana 5/26 | Vairechanika dhuma varti (ingredient of smoke inhalation with unctuous substances) |
| 5 | Cha.Sa.Sutra Sthana 5/63 | Anu taila dravya |
| 6 | Cha.Sa.Sutra Sthana 6/16 | Vihara in Hemanta Rutu |
| 7 | Cha.Sa.Sutra Sthana 6/25 | Vihara in Vasanta Rutu |
| 8 | Cha.Sa.Sutra Sthana 25/40 | Agrya Sangraha (collections of best food articles, factors and drugs) |
| 9 | Cha.Sa.Sutra Sthana 26/49 | Veerya varnan |
| 10 | Cha.Sa.Vimana Sthana 8/143 | Tikta skandha (group of bitter drugs) |
| 11 | Cha.Sa.Sharira Sthana 8/41 | Prajata stree paricharya / Apara patana (post-delivery management) |
| 12 | Cha.Sa.Chikitsa Sthana 6/28 | Used for decoction in Kaphaja prameha (diabetes) |
| 13 | Cha.Sa.Chikitsa Sthana 12/36 | Ingredient in Punarnavadhyarisht |
| 14 | Cha.Sa.Chikitsa Sthana 12/65 | For Lepa, Abhyangadi Bahyaprayogarth (external applications) |
| 15 | Cha.Sa.Chikitsa Sthana 12/70 | As a Lepa dravya in Kaphaj Shvayathu (swelling) |
| 16 | Cha.Sa.Chikitsa Sthana 15/148 | As an ingredient of Madhookasava |
| 17 | Cha.Sa.Chikitsa Sthana 15/163 | As an ingredient of Madhvarishta |
| 18 | Cha.Sa.Chikitsa Sthana 17/80 | Used for shodhanottara dhumapana |
| 19 | Cha.Sa.Chikitsa Sthana 17/123 | As an ingredient of shatyadi churna |
| 20 | Cha.Sa.Chikitsa Sthana 23/77 | As an ingredient of Mahagandha hasti agada |
| 21 | Cha.Sa.Chikitsa Sthana 23/231 | Used in the treatment of animals suffering with poison |
| 22 | Cha.Sa.Chikitsa Sthana 25/91 | As an ingredient of Kampillakadi taila |
| 23 | Cha.Sa.Chikitsa Sthana 26/182 | Used in Kaphaja sira shoola for dhoomavarti |
| 24 | Cha.Sa.Chikitsa Sthana 26/188 | As an ingredient of Pippalyadi churna for kavala karma (gargling) |
| 25 | Cha.Sa.Chikitsa Sthana 26/209 | As an ingredient of Khadiradi gutika |
| 26 | Cha.Sa.Chikitsa Sthana 26/270 | As an ingredient of Mahaneela taila |
| 27 | Cha.Sa.Chikitsa Sthana 27/41 | As an ingredient of Piluparnyadi Yoga |
| 28 | Cha.Sa.Chikitsa Sthana 27/54 | As an ingredient of Vatsakadi Pralepa (external application) |
| 29 | Cha.Sa.Chikitsa Sthana 28/150 | As an ingredient of Bala taila |
| 30 | Cha.Sa.Chikitsa Sthana 28/168 | As an ingredient of Mulakadhya taila |
| 31 | Cha.Sa.Chikitsa Sthana 28/179 | Agurvadi taila is useful in Vata vyadhi |
| 32 | Cha.Sa.Chikitsa Sthana 29/92 | As an ingredient of Madhuparnyadi taila |
| 33 | Cha.Sa.Chikitsa Sthana 29/107 | As an ingredient of Amrutadya taila |
| 34 | Cha.Sa.Kalpa Sthana 1/23 | Vamanarth (for emesis) |
| 35 | Cha.Sa.Chikitsa Sthana 1/1/58 | In formulation of dwitiya brahma rasayana |
| 36 | Cha.Sa.Chikitsa Sthana 2/3/28 | As a mood enhancer |
Therapeutic Indications (Classical)
Aguru is traditionally indicated in the clinical management of:[1]
- Akshiroga (Eye diseases)
- Shwasa (Dyspnea / Respiratory distress)
- Karna roga (Ear diseases)
- Kushtha (Dermatological disorders / Skin diseases)
- Visha (Toxic conditions / Poisoning)
Dosage & Administration
- Powder (Churna): 1 – 3 g daily in divided doses.[1]
Classical Formulations
- Madhukasava
- Mrudvikasava
- Karpuradyarka
- Chyavanprasha avaleha
- Anu taila
- Chandanadi taila
- Khadiradi gutika
- Swasahara kashaya churna
- Guduchyadi taila
Current Researches
Phytochemical Composition
Modern phytochemical profiling of Aquilaria agallocha resinous heartwood reveals a dense matrix of active constituents:
- Sesquiterpenes: Alpha-guaiene, beta-elemene, agarospirol, valencene, and jinkoh-eremol.
- Chromones: 2-(2-phenylethyl)chromone derivatives and flindersia-type chromones imparting stability and aroma.
- Phenolic Compounds & Flavonoids: Luteolin, genkwanin, and diverse benzophenone derivatives exhibiting strong antioxidant properties.
Pharmacological Activities & Therapeutic Efficacy
- Anti-Inflammatory & Analgesic Efficacy: Sesquiterpenes and chromones inhibit lipoxygenase and cyclooxygenase pathways, suppressing inflammatory mediators.[4]
- Neuroprotective & Anxiolytic Actions: Volatile sesquiterpenes cross the blood-brain barrier, interacting positively with GABAergic receptor systems to moderate central nervous system excitability.[4]
- Antimicrobial & Antioxidant Properties: Phenolic fractions and oxygenated sesquiterpenes disrupt microbial membrane integrity while scavenging reactive oxygen species (ROS), validating its efficacy against skin pathogens.[4]
Current Availability
- Available in India, particularly in the Himalayan region, Assam, and Manipur.
References
- ↑ 1.0 1.1 1.2 1.3 The Ayurvedic Pharmacopoeia of India. 4 (Part I ed.). Department of Ayush, Ministry of Health and Family Welfare, Govt. of India. 1986. p. 02.
- ↑ Chunekar, Krushnachandra (2020). Bhavaprakash Nighantu (Reprint ed.). Chaukhambha Bharati Academy. pp. Karpuradi varga, verse no.– 21, 22.
- ↑ Tripathi, Indradev (2006). Raja Nighantu of Pandit Narhari. Varanasi: Chaukhambha Krishnadas Academy. pp. Chandanadi varga verse no– 85, 87, 89, 91, 92.
- ↑ 4.0 4.1 4.2 "Pharmacological evaluation and phytochemical constituents of Aquilaria agallocha". Journal of Ethnopharmacology. 2021.