Changes

=== ''Vidhi Vimarsha'' ===

=== ''Vidhi Vimarsha'' ===

Kshira Dadhi Nyaya (milk-curd transformation phenomena/ analogy)

==== ''Kshira Dadhi Nyaya'' (milk-curd transformation phenomena/ analogy) ====

• The formation of dhatu involves the transformation of rasa into rakta, rakta   into mamsa, etc., in the presence of respective dhatvagni in a similar manner as milk gets converted into curd, curds into butter and butter into ghee. According to Acharya Harita, within seven days rasa gets transformed into Shukra. Even though this theory appears to be hypothetical, recent modern research has shown that this kind of transformation is possible. A team of Japanese and American scientists has managed to convert human skin cells into formed embryos by bathing them in weak citric acid for a duration of 30 minutes . Researchers at Stanford University transformed skin fibroblast cells from mice into working neurons by inserting genes that encode transcription factors . Researchers at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells . More recently, scientists have successfully made immature sperm cells from human bone marrow samples. Therefore, the formation of ‘shukra’ from ‘majja’ is proved by these scientific evidence .

 

• Kedari Kulya Nyaya (vascular network):

*The formation of ''dhatu'' involves the transformation of ''rasa'' into ''rakta, rakta'' into ''mamsa'', etc., in the presence of respective ''dhatvagni'' in a similar manner as milk gets converted into curd, curds into butter and butter into ghee. According to Acharya Harita, within seven days ''rasa'' gets transformed into ''shukra''. Even though this theory appears to be hypothetical, recent modern research has shown that this kind of transformation is possible. A team of Japanese and American scientists has managed to convert human skin cells into formed embryos by bathing them in weak citric acid for a duration of 30 minutes. Researchers at Stanford University transformed skin fibroblast cells from mice into working neurons by inserting genes that encode transcription factors. Researchers at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells . More recently, scientists have successfully made immature sperm cells from human bone marrow samples. Therefore, the formation of ''shukra'' from ''majja'' is proved by these scientific evidence .

According to Kedari kulya Nyaya innumerable microvascular channels transport nourishment to their respective sites in dhatus (tissues) in the body. The cells and tissues are bathed with nutrient plasma. But mere tissue perfusion is not enough to complete the process of nourishment. It needs the complementary play of two subsequent nyayas. (Ch. Su 28/4), (Ch Chi 15/36)

 

• Per modern science, vesicles transport nutrients to the target organs and get controlled by a set of genes (discovered by Randy Schekman). Further, James Rothman found out that protein machinery allows vesicles to fuse with their targets and permits transfer of nutrients to their target tissue. Thomas Sudhof revealed how signals instruct vesicles to release their cargo with precision. Through their discoveries, Rothman, Schekman and Sudhof have revealed the exquisitely precise control system for the transport and delivery of cellular cargo. Disturbances in this system have deleterious effects and contribute to conditions such as neurological diseases, diabetes, and immunological disorders.

==== ''Kedari Kulya Nyaya'' (vascular network) ====

• According to khale kapota nyaya (distribution system), nutrients get directly absorbed by tissues selectively just as pigeons eat the grain of their choice. As per modern research, nutrients are transported to target tissues using vesicles and plasma binding/ transporter proteins when vesicles fuse with target membranes. Cells in those tissues have different organelles that produce various molecules like hormones, neurotransmitters, cytokines and enzymes etc. having specific functions that trigger at the right time and the target site.   

 

• Rakta vibaddhamargatvan maṃsa sinna prapadyate.: If a channel is obstructed, the sequential transformation of tissue is impaired.

*According to ''Kedari Kulya Nyaya'' innumerable microvascular channels transport nourishment to their respective sites in ''dhatus'' (tissues) in the body. The cells and tissues are bathed with nutrient plasma. But mere tissue perfusion is not enough to complete the process of nourishment. It needs the complementary play of two subsequent ''nyayas''. (Ch. Su 28/4), (Ch Chi 15/36)

• Langhana (reducing therapy) is the line of treatment for all the rasaja (body fluids) disorders (Ch. Su. 28/25).  

*Per modern science, vesicles transport nutrients to the target organs and get controlled by a set of genes (discovered by Randy Schekman). Further, James Rothman found out that protein machinery allows vesicles to fuse with their targets and permits transfer of nutrients to their target tissue. Thomas Sudhof revealed how signals instruct vesicles to release their cargo with precision. Through their discoveries, Rothman, Schekman and Sudhof have revealed the exquisitely precise control system for the transport and delivery of cellular cargo. Disturbances in this system have deleterious effects and contribute to conditions such as neurological diseases, diabetes, and immunological disorders.

• Treatment of raktaja (blood) disorders is mentioned in Vidhishōṇitiya Adhyaya (Charaka Saṃhita Sutra sthana 24th chapter). The treatment for raktaja vikara should be planned as per raktapitta, along with virechana, upavasa and raktamokshana (purgation, fasting, and bloodletting) (Ref. Cha. Su. 24/18). (Ch. Su. 28/25)

*According to ''Khale Kapota Nyaya'' (distribution system), nutrients get directly absorbed by tissues selectively just as pigeons eat the grain of their choice. As per modern research, nutrients are transported to target tissues using vesicles and plasma binding/ transporter proteins when vesicles fuse with target membranes. Cells in those tissues have different organelles that produce various molecules like hormones, neurotransmitters, cytokines and enzymes etc. having specific functions that trigger at the right time and the target site.   

• The mamsaja disorders should be treated with purification, surgery, usage of alkali and agnikarma (cauterization) (Ch. Su. 28/26).  

*''Rakta vibaddhamargatvan mamsa sinna prapadyate''.: If a channel is obstructed, the sequential transformation of tissue is impaired.

• The treatment of medoja disorders is mentioned in Aṣṭauninditiya Adhyaya (Charaka Samhita, Sutra sthana 21st chapter). Guru Chatarpanam Dadhyat sthulanam Karshanam Prati diet modification, exercise, purification, and drugs (Cha Su 21/20 (Ch. Su. 28/26)

*''Langhana'' (reducing therapy) is the line of treatment for all the ''rasaja'' (body fluids) disorders (Ch. Su. 28/25).  

*Treatment of ''raktaja'' (blood) disorders is mentioned in [[Vidhishonitiya Adhyaya]] ([[Charaka Samhita]] [[Sutra Sthana]] 24th chapter). The treatment for ''raktaja vikara'' should be planned as per ''raktapitta'', along with ''virechana, upavasa'' and ''raktamokshana'' (purgation, fasting, and bloodletting) (Ref. Cha. Su. 24/18). (Ch. Su. 28/25)

*The ''mamsaja'' disorders should be treated with purification, surgery, usage of alkali and ''agnikarma'' (cauterization) (Ch. Su. 28/26).  

*The treatment of ''medoja'' disorders is mentioned in [[Astauninditiya Adhyaya]] ([[Charaka Samhita]], [[Sutra Sthana]] 21st chapter).

 

Guru Chatarpanam Dadhyat sthulanam Karshanam Prati diet modification, exercise, purification, and drugs (Cha Su 21/20 (Ch. Su. 28/26)

• Asthigata disorders should be treated with [[Panchakarma]], especially basti (enema) prepared from bitter drugs, milk and ghee should be administered (Ch. Su. 28/27).  

• Asthigata disorders should be treated with [[Panchakarma]], especially basti (enema) prepared from bitter drugs, milk and ghee should be administered (Ch. Su. 28/27).  

• Majja and shukragata disorders should be treated with food and drugs having a sweet and bitter taste. Coitus, exercise and timely purification as required should be engaged in (Ch. Su. 28/28).  

• Majja and shukragata disorders should be treated with food and drugs having a sweet and bitter taste. Coitus, exercise and timely purification as required should be engaged in (Ch. Su. 28/28).