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Indrayava and its wet bark is used. It is used mostly in rakta atisara or old ama atisara (Chronic amoebic dysentery), also in raktapitta.
 
Indrayava and its wet bark is used. It is used mostly in rakta atisara or old ama atisara (Chronic amoebic dysentery), also in raktapitta.
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[[File:vatsaka.jpg]]
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[[File:vatsaka.jpg|thumb]]
 
   
 
   
 
'''Latin name''': Holarrhena antidysenterica Linn. Wall.
 
'''Latin name''': Holarrhena antidysenterica Linn. Wall.
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'''Chemical constituents''': Major total alkaloids 4%; bioactive steroidal alkaloid conessine 0.4%; kurchicine, conkurchine, holarrhine. Others- steroidal alkaloids, kurchiline. [11]
 
'''Chemical constituents''': Major total alkaloids 4%; bioactive steroidal alkaloid conessine 0.4%; kurchicine, conkurchine, holarrhine. Others- steroidal alkaloids, kurchiline. [11]
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=== Sanskrit Text, Transliteration with English Translation ===
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== Sanskrit Text, Transliteration with English Translation ==
 
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Now (I) shall expound the chapter on pharmaceutical preparations of ''vatsaka''. Thus said Lord Atreya.[1-2]
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Now we shall expound the chapter "Vatsaka kalpa"(Pharmaceutical preparations of Vatsaka). Thus said Lord Atreya.[1-2]
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==== Types and synonyms of ''vatsaka'' ====
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=== Types and synonyms of ''vatsaka'' ===
 
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''Vatsaka'' destroys ''raktapitta'' and ''kapha'', is free from harmful effects and as such useful for the delicate persons. It is indicated in cardiac disorders, fever, ''vatarakta,'' erysipelas etc.[6]
 
''Vatsaka'' destroys ''raktapitta'' and ''kapha'', is free from harmful effects and as such useful for the delicate persons. It is indicated in cardiac disorders, fever, ''vatarakta,'' erysipelas etc.[6]
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==== Various preparations ====
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=== Various preparations ===
 
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The powder may be taken with water of mustard, madhuka or salt. Or the physician may administer it as emetic mixed with ''krishara''.[11]
 
The powder may be taken with water of mustard, madhuka or salt. Or the physician may administer it as emetic mixed with ''krishara''.[11]
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==== Summary ====
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=== Summary ===
 
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== Vidhi Vimarsha (Applied Inferences ) ==
 
== Vidhi Vimarsha (Applied Inferences ) ==
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==== Synomyms of ''vatsaka'' ====
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=== Synomyms of ''vatsaka'' ===
    
*Vatsaka – It is called because it grows in hilly regions of Vatsa.
 
*Vatsaka – It is called because it grows in hilly regions of Vatsa.
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Synonyms according to Dhanvantari Nighantu – kautaja, kauta, vatsaka, girimallika, kalinga, mallika pushpa, indravriksha and vriksaka.[13]
 
Synonyms according to Dhanvantari Nighantu – kautaja, kauta, vatsaka, girimallika, kalinga, mallika pushpa, indravriksha and vriksaka.[13]
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==== Cause and effect ====
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=== Cause and effect ===
    
It is useful in ''raktapitta'' due to ''sheeta veerya'' and pacifies the ''kapha'' due to ''laghu, ruksha guna; tikta, kashaya rasa'' and ''katu vipaka''.  
 
It is useful in ''raktapitta'' due to ''sheeta veerya'' and pacifies the ''kapha'' due to ''laghu, ruksha guna; tikta, kashaya rasa'' and ''katu vipaka''.  
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The alkaloids in ''vatsaka'' have as powerful action as emetic in their immediate effect on the symptoms of intestinal amoebiasis as well as in their curative value, in such  doses as one grain daily by intramuscular injections. [14]
 
The alkaloids in ''vatsaka'' have as powerful action as emetic in their immediate effect on the symptoms of intestinal amoebiasis as well as in their curative value, in such  doses as one grain daily by intramuscular injections. [14]
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==== Recent researches on action of herbs ====
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=== Recent researches on action of herbs ===
    
In a research study (Chavan S.et.al., 2014), good improvement by observed by therapeutic emesis with ''vatsaka'' in patient of acne vulgaris. ''Indrayava churna'' in the quantity of 24 gm (''Antarnakhamushi''-closed fist) impregnated with the decoction of ''madhuka'' (Glycyrrhiza glabra Linn.) 160 ml kept there in for whole night. In the next morning it was be crushed and added with salt 10gm and honey 25 gm. The total quantity goes up to 219 ml approximately. The study concluded with following observations:
 
In a research study (Chavan S.et.al., 2014), good improvement by observed by therapeutic emesis with ''vatsaka'' in patient of acne vulgaris. ''Indrayava churna'' in the quantity of 24 gm (''Antarnakhamushi''-closed fist) impregnated with the decoction of ''madhuka'' (Glycyrrhiza glabra Linn.) 160 ml kept there in for whole night. In the next morning it was be crushed and added with salt 10gm and honey 25 gm. The total quantity goes up to 219 ml approximately. The study concluded with following observations:
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[[File:Indravayakalpa.jpg|500px]]
 
[[File:Indravayakalpa.jpg|500px]]
 
   
 
   
'''Future scope of research''': Pharmacological properties showed antihyperglycemic and antihyperlipidemic  and clinical trial should be conducted especially as emetic in psoriasis, diabetes mellitus, metabolic syndrome, hypercholesterolemia.
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===Future scope of research===
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=== References ===
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There is much scope to study anti-hyperglycemic and anti-hyperlipidemic effect. Clinical trial may be conducted to study effect of vatsaka as emetic in psoriasis, diabetes mellitus, metabolic syndrome, hypercholesterolemia.
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=== Further reading ===
    
#Prof. P.V. Sharma, Dravyaguna- Vigyana, Vol.II, Chaukhambha Bharati Academy, Varanasi, Reprint 1998, pp 464.  
 
#Prof. P.V. Sharma, Dravyaguna- Vigyana, Vol.II, Chaukhambha Bharati Academy, Varanasi, Reprint 1998, pp 464.  
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#Dhanvantari Nighantu, Shatpushpadi Varga, 6/13, edited by Prof. P.V. Sharma, Chaukhambha [[Ayurveda]] Pratishthan, Varanasi, Reprint 2008,  72.
 
#Dhanvantari Nighantu, Shatpushpadi Varga, 6/13, edited by Prof. P.V. Sharma, Chaukhambha [[Ayurveda]] Pratishthan, Varanasi, Reprint 2008,  72.
 
#Indian Medicinal Plants, Vol.II, by K.R. Kirtikar and B.D. Basu, 1998, 1572.
 
#Indian Medicinal Plants, Vol.II, by K.R. Kirtikar and B.D. Basu, 1998, 1572.
#Chavan Santosh (2014), Study of Vaman Karma in Indrayava Kalpa in Yuvan pidaka (Acne vulgaris). Thesis research work at Department of Panchakarma of Bharati Vidyapeeth Deemed University College of [[Ayurveda]], Pune.
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#Chavan Santosh (2014). Study of Vaman Karma in Indrayava Kalpa in Yuvan pidaka (Acne vulgaris). Thesis research work at Department of Panchakarma of Bharati Vidyapeeth Deemed University College of [[Ayurveda]], Pune.
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