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Varna (view source)

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== Classification ==

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Human skin colour ranges from the darkest brown to the lightest hues. [[Ayurveda|Ayurveda]] scholars have classified varna based on proportions of ~~mahabhutacomposing~~ them as follows:

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Human skin colour ranges from the darkest brown to the lightest hues. [[Ayurveda|Ayurveda]] scholars have classified varna based on proportions of [[Pancha mahabhuta|mahabhuta]] composing them as follows:

{| class="wikitable"

! S. No

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{| class="wikitable"

! Varna

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! Mahabhuta Acc. To Charak

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! [[Pancha mahabhuta|Mahabhuta]] Acc. To Charak

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! Mahabhuta Acc. To Susruta

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! [[Pancha mahabhuta|Mahabhuta]] Acc. To Susruta

|-

| Gaura

−

| Agni+Jala+Akash

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| [[Agni mahabhuta|Agni]]+[[Jala mahabhuta|Jala]]+[[Akasha mahabhuta|Akash]]

−

| Jala+Agni

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| [[Jala mahabhuta|Jala]]+[[Agni mahabhuta|Agni]]

|-

| Krishna

−

| Agni+Prithvi+Vayu

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| [[Agni mahabhuta|Agni]]+[[Prithvi mahabhuta|Prithvi]]+[[Vayu mahabhuta|Vayu]]

−

| Prithvi+Agni

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| [[Prithvi mahabhuta|Prithvi]]+[[Agni mahabhuta|Agni]]

|-

| Shyam

−

| Akash+Vayu+Agni+Jala+Prithvi

+

|

|-

| Gaura Shyam

|

−

| Jala+Akash+Agni

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| [[Jala mahabhuta|Jala]]+[[Akasha mahabhuta|Akash]]+[[Agni mahabhuta|Agni]]

|-

| Krishna Shyam

|

−

| Prithvi+Akash+Agni

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| [[Prithvi mahabhuta|Prithvi]]+[[Akasha mahabhuta|Akash]]+[[Agni mahabhuta|Agni]]

|-

|}

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== Inheritance of varna ==

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The disorders of various [[Sharira|body]] systems affect varna. E.g. disorders in rakta dhatu (blood and its components) results in skin discolouration and diseases.[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 28/11-13] [Su. Sa. [[Sutra Sthana|Sutra Sthana]] 24/11]Skin diseases have detrimental effect on varna. Rakta dhatu in its optimum quantity and quality leads to superior complexion. Similarly,presence of optimum [[Sharira|body]] and scalp hair, cutaneous blood vessels, too affect the varna. The health of liver, spleen and other digestive organs is important to maintain a normal varna. These organs like heart, liver, spleen are originated from maternal factors, while some like hair, blood vessels, etc are contributed by paternal factors.[Ast. Hri. [[Sharira Sthana|ShariraSthana]] 3/4-5] Thus varna of child is believed to be inherited from parents. Contemporary science believes that three classes of genes contribute to normal human color variation through the production of hypopigmented phenotypes or by genetic association with skin type and hair color. The MSH cell surface receptor and the melanosomal P-protein are the two most obvious candidate genes influencing variation in pigmentation phenotype, and may do so by regulating the levels and activities of the melanogenic enzymes tyrosinase, TRP-1 and TRP-2. Varna being regulated by genes may indicate its inheritance from parents.<ref name="ref1">Sturm R, Box N, Ramsay M. Human pigmentation genetics: the difference is only skin deep. doi:10.1002/(SICI)1521-1878(199809)20.</ref>

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The disorders of various [[Sharira|body]] systems affect varna. E.g. disorders in [[Rakta dhatu|rakta dhatu]] (blood and its components) results in skin discolouration and [[Vyadhi|diseases]].[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 28/11-13] [Su. Sa. [[Sutra Sthana|Sutra Sthana]] 24/11] Skin [[Vyadhi|diseases]] have detrimental effect on varna. [[Rakta dhatu|Rakta dhatu]] in its optimum quantity and quality leads to superior complexion. Similarly, presence of optimum [[Sharira|body]] and scalp hair, cutaneous blood vessels, too affect the varna. The health of liver, spleen and other digestive organs is important to maintain a normal varna. These organs like heart, liver, spleen are originated from maternal factors, while some like hair, blood vessels, etc are contributed by paternal factors.[Ast. Hri. [[Sharira Sthana|ShariraSthana]] 3/4-5] Thus varna of child is believed to be inherited from parents. Contemporary science believes that three classes of genes contribute to normal human color variation through the production of hypopigmented phenotypes or by genetic association with skin type and hair color. The MSH cell surface receptor and the melanosomal P-protein are the two most obvious candidate genes influencing variation in pigmentation phenotype, and may do so by regulating the levels and activities of the melanogenic enzymes tyrosinase, TRP-1 and TRP-2. Varna being regulated by genes may indicate its inheritance from parents.<ref name="ref1">Sturm R, Box N, Ramsay M. Human pigmentation genetics: the difference is only skin deep. doi:10.1002/(SICI)1521-1878(199809)20.</ref>

== Effect of gestational diet pattern on varna of baby ==

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The gestational diet and behaviour of mother influence varna of the new born child. Foetus gets nutrition from the mother; hence the diet and regimen of pregnant woman has a strong importance on the varna of offspring. During the gestational period, if the mother indulges in sweet foods such as milk, the colour of the child will be whitish-yellow; indulgence in foods which cause heart burn, such as sesame will lead to black colour of the child; and the use of mixed types of food will result in blue-black colour of the child.[A. Sam. [[Sharira Sthana|ShariraSthana]] 1/61]<ref name="ref2">Mitra J, editor, (1st ed.). Sasilekha Sanskrit Commentary by Indu on Astanga Samgrah of Vriddha Vagbhata, Sharir Sthana; Putrakamiyo Adhyaya: Chapter 1, Verse 61. Varanasi: Chowkhamba Sanskrit Series Office, 2016; 273.</ref> A 2003 study found that diet of female mouse can change her offspring's coat colour by permanently modifying DNA methylation.<ref name="ref3">Dominguez-Salas P, Moore SE, Baker MS, Bergen AW, Cox SE, Dyer RA, Fulford AJ, Guan Y, Laritsky E, Silver MJ, Swan GE, Zeisel SH, Innis SM, Waterland RA, Prentice AM, Hennig BJ. Maternal nutrition at conception modulates DNA methylation of human metastable epialleles. Nat Commun. 2014 Apr 29;5:3746. doi: 10.1038/ncomms4746. PMID: 24781383; PMCID: PMC4015319.</ref> [[Ayurveda|Ayurveda]] considers that the varna of foetus gets enhanced in sixth month of gestational period and the varna of the mother simultaneously gets decreased during sixth month.[Cha. Sa. [[Sharira Sthana|ShariraSthana]] 4/22] The varna of child also depends on the colour of the apparel usedby mother during pregnancy. [Cha. Sa. [[Sharira Sthana|ShariraSthana]] 8/12] However, more understanding and researches are needed on this concept. Satmya is the suitability towards the diet and regimens consumed by mother during the period of pregnancy. Satmyaja factors have a great impact in the formation of varna.[Cha. Sa. [[Sharira Sthana|ShariraSthana]] 3/11]

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The gestational diet and behaviour of mother influence varna of the new born child. Foetus gets nutrition from the mother; hence the diet and regimen of pregnant woman has a strong importance on the varna of offspring. During the gestational period, if the mother indulges in sweet foods such as milk, the colour of the child will be whitish-yellow; indulgence in foods which cause heart burn, such as sesame will lead to black colour of the child; and the use of mixed types of food will result in blue-black colour of the child.[A. Sam. [[Sharira Sthana|ShariraSthana]] 1/61]<ref name="ref2">Mitra J, editor, (1st ed.). Sasilekha Sanskrit Commentary by Indu on Astanga Samgrah of Vriddha Vagbhata, Sharir Sthana; Putrakamiyo Adhyaya: Chapter 1, Verse 61. Varanasi: Chowkhamba Sanskrit Series Office, 2016; 273.</ref> A 2003 study found that diet of female mouse can change her offspring's coat colour by permanently modifying DNA methylation.<ref name="ref3">Dominguez-Salas P, Moore SE, Baker MS, Bergen AW, Cox SE, Dyer RA, Fulford AJ, Guan Y, Laritsky E, Silver MJ, Swan GE, Zeisel SH, Innis SM, Waterland RA, Prentice AM, Hennig BJ. Maternal nutrition at conception modulates DNA methylation of human metastable epialleles. Nat Commun. 2014 Apr 29;5:3746. doi: 10.1038/ncomms4746. PMID: 24781383; PMCID: PMC4015319.</ref> [[Ayurveda|Ayurveda]] considers that the varna of foetus gets enhanced in sixth month of gestational period and the varna of the mother simultaneously gets decreased during sixth month.[Cha. Sa. [[Sharira Sthana|ShariraSthana]] 4/22] The varna of child also depends on the colour of the apparel usedby mother during pregnancy. [Cha. Sa. [[Sharira Sthana|ShariraSthana]] 8/12] However, more understanding and researches are needed on this concept. [[Satmya|Satmya]] is the suitability towards the diet and regimens consumed by mother during the period of pregnancy. Satmyaja factors have a great impact in the formation of varna.[Cha. Sa. [[Sharira Sthana|ShariraSthana]] 3/11]

== Prakriti vis-a-vis varna ==

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Though the complexion of a person is an outcome of many factors such as humidity, temperature, race, occupation, etc. but [[Prakriti|prakriti]] (constitution) of individuals pre-dominantly affects his complexion. Since vata dosha is dry, rough and cold in nature due to predominance of vayumahabhuta, vata [[Prakriti|prakriti]] individuals are more prone to have lustreless, dry dusky complexion.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/98] [Ast. Hri. [[Sharira Sthana|SharirSthana]] 3/85] Since [[Pitta dosha|pitta dosha]] is unctuous, hot, and fluid in nature due to predominance of agnimahabhuta, [[Pitta dosha|pitta]] [[Prakriti|prakriti]] individuals are prone to have fair complexion, with freckles and blackmoles.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/97] [Ast. Hri. [[Sharira Sthana|ShariraSthana]] 3/90] Since kapha dosha is unctuous, smooth, soft, cold and clear due to predominance of jalamahabhuta, kapha [[Prakriti|prakriti]] individuals are prone to have a pleasing smooth fair complexion with lustre, comparable to gorochan (an auspicious yellow pigment collected from ox), lotus or gold. [Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/96] [Ast. Hri. [[Sharira Sthana|SharirSthana]] 3/97] Thus the specific complexion in specific [[Prakriti|prakriti]] may be attributed to the composition of their respective predominant [[Dosha|dosha]]. The [[Prakriti|prakriti]] depends on genetic constitution of a person. Fewresearches have identified the genome responsible for imparting skin colour. Several genome-wide association studies for pigmentation have now been conducted and identified single nucleotide polymorphism (SNP) markers in known, TYR, TYRP1, OCA2, SLC45A2, SLC24A5, MC1R, ASIP, KITLG and previously unknown SLC24A4, IRF4, TPCN2, candidate genes.<ref name="ref4">Pavan WJ, Sturm RA. The Genetics of Human Skin and Hair Pigmentation. Annu Rev Genomics Hum Genet. 2019 Aug 31;20:41-72. doi: 10.1146/annurev-genom-083118-015230. Epub 2019 May 17. PMID: 31100995.</ref><ref name="ref5">Sturm RA. Molecular genetics of human pigmentation diversity. Hum Mol Genet. 2009 Apr 15;18(R1):R9-17. doi: 10.1093/hmg/ddp003. PMID: 19297406.</ref>

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Though the complexion of a person is an outcome of many factors such as humidity, temperature, race, occupation, etc. but [[Prakriti|prakriti]] (constitution) of individuals pre-dominantly affects his complexion. Since [[Vata dosha|vata dosha]] is dry, rough and cold in nature due to predominance of [[Vayu mahabhuta|vayumahabhuta]], [[Vata dosha|vata]] [[Prakriti|prakriti]] individuals are more prone to have lustreless, dry dusky complexion.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/98] [Ast. Hri. [[Sharira Sthana|SharirSthana]] 3/85] Since [[Pitta dosha|pitta dosha]] is unctuous, hot, and fluid in nature due to predominance of [[Agni mahabhuta|agnimahabhuta]], [[Pitta dosha|pitta]] [[Prakriti|prakriti]] individuals are prone to have fair complexion, with freckles and blackmoles.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/97] [Ast. Hri. [[Sharira Sthana|ShariraSthana]] 3/90] Since [[Kapha dosha|kapha dosha]] is unctuous, smooth, soft, cold and clear due to predominance of [[Jala mahabhuta|jalamahabhuta]], [[Kapha dosha|kapha]] [[Prakriti|prakriti]] individuals are prone to have a pleasing smooth fair complexion with lustre, comparable to gorochan (an auspicious yellow pigment collected from ox), lotus or gold. [Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/96] [Ast. Hri. [[Sharira Sthana|SharirSthana]] 3/97] Thus the specific complexion in specific [[Prakriti|prakriti]] may be attributed to the composition of their respective predominant [[Dosha|dosha]]. The [[Prakriti|prakriti]] depends on genetic constitution of a person. Fewresearches have identified the genome responsible for imparting skin colour. Several genome-wide association studies for pigmentation have now been conducted and identified single nucleotide polymorphism (SNP) markers in known, TYR, TYRP1, OCA2, SLC45A2, SLC24A5, MC1R, ASIP, KITLG and previously unknown SLC24A4, IRF4, TPCN2, candidate genes.<ref name="ref4">Pavan WJ, Sturm RA. The Genetics of Human Skin and Hair Pigmentation. Annu Rev Genomics Hum Genet. 2019 Aug 31;20:41-72. doi: 10.1146/annurev-genom-083118-015230. Epub 2019 May 17. PMID: 31100995.</ref><ref name="ref5">Sturm RA. Molecular genetics of human pigmentation diversity. Hum Mol Genet. 2009 Apr 15;18(R1):R9-17. doi: 10.1093/hmg/ddp003. PMID: 19297406.</ref>

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== Excellence of body tissues (sara) vis-a-vis varna ==

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== Excellence of body tissues ([[Sara|sara]]) vis-a-vis varna ==

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The excellence of dhatus (body tissues) is studied with reference to sara. Sara is classified into eight categories. Among these eight categories, twak sara (excellence in rasa dhatu) individuals have unctuous, smooth, soft, clear, fine, less numerous, deep rooted and tender hair with lustrous skin.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/103] Rasa dhatu is rich in jalamahabhuta imparting smoothness, softness and unctuousness to the skin. Rakta sara (excellence in rakta dhatu) individuals have unctuousness, red colour, beautiful dazzling appearance of the ears, eyes, face, tongue, nose, lips, sole of the hand and feet, nails, forehead and genital organs.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/104]These individuals are believed to have well developed intra-dermal blood capillaries and circulation along with overall excellence in blood vascular system. Meda sara (excellence in meda dhatu) individuals have unctuousness in complexion, eyes, scalp hair and other parts of the [[Sharira|body]], nails, teeth, lips, urine and faeces.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/106] These individuals have excellence in adipose tissue which is unctuous in nature. Majja sara (excellence in majja dhatu) individuals too have unctuous complexion.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/108] Majja dhatu is predominantly formed of jalamahabhuta. Shukra sara (excellence in shukra dhatu) individuals have a gentle look, having eyes as if filled with milk, cheerfulness, having teeth which are unctuous, round, strong, even, beautiful, clean and have unctuous complexion with dazzling appearance.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/109] Shukra dhatu or reproductive tissues are believed to be formed at the end from essence of all other dhatus. Thus it indicate the excellence of all dhatus.

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The excellence of [[Dhatu|dhatus (body tissues)]] is studied with reference to [[Sara|sara]]. [[Sara|Sara]] is classified into eight categories. Among these eight categories, twak [[Sara|sara]] (excellence in rasa dhatu) individuals have unctuous, smooth, soft, clear, fine, less numerous, deep rooted and tender hair with lustrous skin.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/103] Rasa dhatu is rich in [[Jala mahabhuta|jalamahabhuta]] imparting smoothness, softness and unctuousness to the skin. Rakta [[Sara|sara]] (excellence in [[Rakta dhatu|rakta dhatu]]) individuals have unctuousness, red colour, beautiful dazzling appearance of the ears, eyes, face, tongue, nose, lips, sole of the hand and feet, nails, forehead and genital organs.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/104] These individuals are believed to have well developed intra-dermal blood capillaries and circulation along with overall excellence in blood vascular system. [[Meda dhatu|Meda]] [[Sara|sara]] (excellence in [[Meda dhatu|meda dhatu]]) individuals have unctuousness in complexion, eyes, scalp hair and other parts of the [[Sharira|body]], nails, teeth, lips, urine and faeces.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/106] These individuals have excellence in adipose tissue which is unctuous in nature. [[Majja dhatu|Majja]] [[Sara|sara]] (excellence in [[Majja dhatu|majja dhatu]]) individuals too have unctuous complexion.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/108] [[Majja dhatu|Majja dhatu]] is predominantly formed of [[Jala mahabhuta|jalamahabhuta]]. [[Shukra dhatu|Shukra]] [[Sara|sara]] (excellence in [[Shukra dhatu|shukra dhatu]]) individuals have a gentle look, having eyes as if filled with milk, cheerfulness, having teeth which are unctuous, round, strong, even, beautiful, clean and have unctuous complexion with dazzling appearance.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/109] [[Shukra dhatu|Shukra dhatu]] or reproductive tissues are believed to be formed at the end from essence of all other [[Dhatu|dhatus]]. Thus it indicate the excellence of all [[Dhatu|dhatus]].

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== Effect of dinacharya(daily regimen) on varna ==

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== Effect of [[Dinacharya|dinacharya(daily regimen)]] on varna ==

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A healthy daily regimen helps in maintaining a healthy varna. These regimens include following: Consumption of food in proper quantity[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 5/8] Applying udvartana (massaging the [[Sharira|body]] with soft, fragrant powder) [Ast. Hri. [[Sutra Sthana|Sutra Sthana]] 2/15] Maintaining the three supports of life viz. food, sleep and brahmacharya (avoidance of sexual act physically, mentally and verbally in all ways under any circumstances) in life[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 11/35] Use of rasayana[Cha. Sa. ChikitsaSthana 1/1/7] (the drug, food or therapy which has capacity to prevent ageing, improve longevity, provide immunity against the diseases, promote mental competence, increase vitality and lustre of the [[Sharira|body]]) Jatharagni (digestive capacity) is also responsible for complexion [Cha. Sa. ChikitsaSthana 15/3], hence such diet should be consumed which establishes a healthy jatharagni. Importance of diet in imparting good complexion is mentioned.[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/349] [Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/3]. The food that is consumed is digested by jatharagni. This digestion produces nourishment to the dhatus (tissues) of the [[Sharira|body]]. Healthy tissues are responsible for maintenance of healthy skin, thus indicating role of jatharagni in varna.

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A healthy daily regimen helps in maintaining a healthy varna. These regimens include following: Consumption of food in proper quantity[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 5/8] Applying udvartana (massaging the [[Sharira|body]] with soft, fragrant powder) [Ast. Hri. [[Sutra Sthana|Sutra Sthana]] 2/15] Maintaining the three supports of life viz. food, sleep and brahmacharya (avoidance of sexual act physically, mentally and verbally in all ways under any circumstances) in life[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 11/35] Use of rasayana[Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 1/1/7] (the drug, food or therapy which has capacity to prevent ageing, improve longevity, provide immunity against the [[Vyadhi|diseases]], promote mental competence, increase vitality and lustre of the [[Sharira|body]]) Jatharagni (digestive capacity) is also responsible for complexion [Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 15/3], hence such diet should be consumed which establishes a healthy jatharagni. Importance of diet in imparting good complexion is mentioned.[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/349] [Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/3]. The food that is consumed is digested by jatharagni. This digestion produces nourishment to the [[Dhatu|dhatus (tissues)]] of the [[Sharira|body]]. Healthy tissues are responsible for maintenance of healthy skin, thus indicating role of jatharagni in varna.

== Ojas & varna ==

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Ojas is the essence of the body tissues (dhatus) [Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/24]. As healthy state of all dhatu keeps the skin healthy.Thusone of the functions of ojas is to maintain varna.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/25] The qualitative deterioration (ojavyapat) causes impairment of complexion.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/29]

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Ojas is the essence of the [[Dhatu|body tissues (dhatus)]] [Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/24]. As healthy state of all dhatu keeps the skin healthy.Thusone of the functions of ojas is to maintain varna.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/25] The qualitative deterioration (ojavyapat) causes impairment of complexion.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/29]

== Varna as an atmaja bhava ==

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== Importance of concept ==

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=== Importance in diagnosis & prognosis of disease ===

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=== Importance in diagnosis & prognosis of [[Vyadhi|disease]] ===

The natural complexion indicates a state of health or natural physiological processes inside the [[Sharira|body]]. Sudden spontaneous change in natural complexion may be due to some pathology. Sudden drastic change in natural complexion may also indicate death in near future. Apart from discussing the natural complexion, some of the abnormal complexions like blue, grey, coppery, green and albino (extremely white) are described. [Cha. Sa. [[Indriya Sthana|IndriyaSthana]] 1/9] Example, cyanotic complexion is observed in severe right ventricular hypertrophic cardiomyopathy.<ref name="ref6">Li M, Zhang L, Zhang Z, Wang S, Dong N, Wang G, Xie M. Isolated Severe Right Ventricular Hypertrophic Cardiomyopathy. Ann Thorac Surg. 2019 Jan;107(1):e23-e25. doi: 10.1016/j.athoracsur.2018.05.061. Epub 2018 Jun 23. PMID: 29944878.</ref> The abnormalities include if half of the [[Sharira|body]] has natural complexion and the other have abnormal complexion, and both of them are evenly demarcated by a line. These normal and abnormal complexions may simultaneously appear in left and right sides, front and back sides, upper and lower parts or internal and external parts of the [[Sharira|body]]. Natural and abnormal complexions simultaneously appearing in face or other parts of the [[Sharira|body]], are the morbid signs indicating imminent death.[Cha. Sa. [[Indriya Sthana|IndriyaSthana]] 1/10] For example, amelanotic melanomas presenting as red skin lesions are often lethal.<ref name="ref7">McClain SE, Mayo KB, Shada AL, Smolkin ME, Patterson JW, Slingluff CL Jr. Amelanotic melanomas presenting as red skin lesions: a diagnostic challenge with potentially lethal consequences. Int J Dermatol. 2012 Apr;51(4):420-6. doi: 10.1111/j.1365-4632.2011.05066.x. PMID: 22435430; PMCID: PMC4465919.</ref>

=== Clinical diagnosis based on varna ===

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Some diseases often have an impact on varna. Thus varna can be used as one of the diagnostic criterias for identification of diseases. Examples are as follows:

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Some [[Vyadhi|diseases]] often have an impact on varna. Thus varna can be used as one of the diagnostic criterias for identification of [[Vyadhi|diseases]]. Examples are as follows:

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* Pandu (anaemia); Pale colour. [Cha. Sa. ChikitsaSthana 16/11]

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* Pandu (anaemia); Pale colour. [Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 16/11]

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* Kamla (jaundice): Yellowish [Cha. Sa. ChikitsaSthana 16/35]

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* Kamla (jaundice): Yellowish [Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 16/35]

* Vitiligo: Depigmented patches over skin.

* Albinism: Depigmentation of skin.

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Melanin is produced by melanocytes in a process called melanogenesis. Melanin is made within small membrane–bound packages called melanosomes. As they become full of melanin, they move into the slender arms of melanocytes, from where they are transferred to the keratinocytes. Under normal conditions, melanosomes cover the upper part of the keratinocytes and protect them from genetic damage. One melanocyte supplies melanin to thirty-six keratinocytes according to signals from the keratinocytes. They also regulate melanin production and replication of melanocytes.<ref name="ref8">Jablonski, Nina (2012). Living Color. Berkeley, Los Angeles, London: University of California Press. ISBN 978-0-520-25153-3.</ref>Individuals have different skin colours mainly because their melanocytes produce different amount and kinds of melanin. The genetic mechanism behind human skin colour is mainly regulated by the enzyme tyrosinase, which creates the colour of the skin, eyes, and hair shades.<ref name="ref9">Sturm, R. A. (2006). "A golden age of human pigmentation genetics". Trends in Genetics. 22 (9): 464–469. doi:10.1016/j.tig.2006.06.010. PMID 16857289</ref>,<ref name="ref10">Sturm, R. A.; Teasdale, R. D.; Box, N. F. (2001). "Human pigmentation genes: Identification, structure and consequences of polymorphic variation". Gene. 277 (1–2): 49–62. doi:10.1016/s0378-1119(01)00694-1. PMID 11602344</ref> Differences in skin colour are also attributed to differences in size and distribution of melanosomes in the skin.<ref name="ref11">Jablonski, Nina (2012). Living Color. Berkeley, Los Angeles, London: University of California Press. ISBN 978-0-520-25153-3.</ref>Both the amount and type of melanin produced is controlled by a number of genes that operate under incomplete dominance.<ref name="ref12">Schneider, Patricia (2003). "The Genetics and Evolution of Skin Color: The Case of Desiree's Baby". RACE—The Power of an Illusion. Public Broadcasting Service. Archived from the original on 6 May 2015. Retrieved 14 April 2015.</ref> One copy of each of the various genes is inherited from each parent. Each gene can come in several alleles, resulting in the great variety of human skin tones.

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== Excellence of body tissues (sara) vis-a-vis varna: ==

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== Excellence of body tissues ([[Sara|sara]]) vis-a-vis varna: ==

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The excellence of dhatus (body tissues) is studied with reference to sara. Sara is classified into eight categories. Among these eight categories, twak sara (excellence in rasa dhatu) individuals have unctuous, smooth, soft, clear, fine, less numerous, deep rooted and tender hair with lustrous skin.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/103] Rasa dhatu is rich in ~~jalamahabhutaimparting~~ smoothness,softness and unctuousness to the skin. Rakta sara (excellence in rakta dhatu) individuals have unctuousness, red colour, beautiful dazzling appearance of the ears, eyes, face, tongue, nose, lips, sole of the hand and feet, nails, forehead and genital organs.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/104] These individuals are believed to have well developed intra-dermal blood capillaries and circulation along with overall excellence in blood vascular system. Meda sara (excellence in meda dhatu) individuals have unctuousness in complexion, eyes, scalp hair and other parts of the [[Sharira|body]], nails, teeth, lips, urine and faeces.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/106] These individuals have excellence in adipose tissue which is unctuous in nature. Majja sara (excellence in majja dhatu) individuals too have unctuous complexion.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/108] Majja dhatu is predominantly formed of jalamahabhuta. Shukra sara (excellence in shukra dhatu) individuals have a gentle look, having eyes as if filled with milk, cheerfulness, having teeth which are unctuous, round, strong, even, beautiful, clean and have unctuous complexion with dazzling appearance.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/109] Shukra dhatu or reproductive tissues are believed to be formed at the end from essence of all other dhatus. Thus it indicate the excellence of all dhatus.

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The excellence of [[Dhatu|dhatus (body tissues)]] is studied with reference to [[Sara|sara]]. [[Sara|Sara]] is classified into eight categories. Among these eight categories, twak [[Sara|sara]] (excellence in rasa dhatu) individuals have unctuous, smooth, soft, clear, fine, less numerous, deep rooted and tender hair with lustrous skin.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/103] Rasa dhatu is rich in [[Jala mahabhuta|jalamahabhuta]] imparting smoothness, softness and unctuousness to the skin. Rakta [[Sara|sara]] (excellence in [[Rakta dhatu|rakta dhatu]]) individuals have unctuousness, red colour, beautiful dazzling appearance of the ears, eyes, face, tongue, nose, lips, sole of the hand and feet, nails, forehead and genital organs.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/104] These individuals are believed to have well developed intra-dermal blood capillaries and circulation along with overall excellence in blood vascular system. [[Meda dhatu|Meda]] [[Sara|sara]] (excellence in [[Meda dhatu|meda dhatu]]) individuals have unctuousness in complexion, eyes, scalp hair and other parts of the [[Sharira|body]], nails, teeth, lips, urine and faeces.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/106] These individuals have excellence in adipose tissue which is unctuous in nature. [[Majja dhatu|Majja]] [[Sara|sara]] (excellence in [[Majja dhatu|majja dhatu]]) individuals too have unctuous complexion.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/108] [[Majja dhatu|Majja dhatu]] is predominantly formed of [[Jala mahabhuta|jalamahabhuta]]. [[Shukra dhatu|Shukra]] [[Sara|sara]] (excellence in [[Shukra dhatu|shukra dhatu]]) individuals have a gentle look, having eyes as if filled with milk, cheerfulness, having teeth which are unctuous, round, strong, even, beautiful, clean and have unctuous complexion with dazzling appearance.[Cha. Sa. [[Vimana Sthana|VimanaSthana]] 8/109] [[Shukra dhatu|Shukra dhatu]] or reproductive tissues are believed to be formed at the end from essence of all other [[Dhatu|dhatus]]. Thus it indicate the excellence of all [[Dhatu|dhatus]].

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== Effect of dinacharya(daily regimen) on varna ==

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== Effect of [[Dinacharya|dinacharya(daily regimen)]] on varna ==

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A healthy daily regimen helps in maintaining a healthy varna. These regimens include following: Consumption of food in proper quantity[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 5/8] Applying udvartana (massaging the [[Sharira|body]] with soft, fragrant powder) [Ast. Hri. [[Sutra Sthana|Sutra Sthana]] 2/15] Maintaining the three supports of life viz. food, sleep and brahmacharya (avoidance of sexual act physically, mentally and verbally in all ways under any circumstances) in life[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 11/35] Use of rasayana[Cha. Sa. ChikitsaSthana 1/1/7] (the drug, food or therapy which has capacity to prevent ageing, improve longevity, provide immunity against the diseases, promote mental competence, increase vitality and lustre of the [[Sharira|body]]). Jatharagni (digestive capacity) is also responsible for complexion [Cha. Sa. ChikitsaSthana 15/3], hence such diet should be consumed which establishes a healthy jatharagni. Importance of diet in imparting good complexion is mentioned.[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/349] [Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/3]. The food that is consumed is digested by jatharagni. This digestion produces nourishment to the dhatus (tissues) of the [[Sharira|body]]. Healthy tissues are responsible for maintenance of healthy skin, thus indicating role of jatharagni in varna.

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A healthy daily regimen helps in maintaining a healthy varna. These regimens include following: Consumption of food in proper quantity[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 5/8] Applying udvartana (massaging the [[Sharira|body]] with soft, fragrant powder) [Ast. Hri. [[Sutra Sthana|Sutra Sthana]] 2/15] Maintaining the three supports of life viz. food, sleep and brahmacharya (avoidance of sexual act physically, mentally and verbally in all ways under any circumstances) in life[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 11/35] Use of rasayana[Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 1/1/7] (the drug, food or therapy which has capacity to prevent ageing, improve longevity, provide immunity against the [[Vyadhi|diseases]], promote mental competence, increase vitality and lustre of the [[Sharira|body]]). Jatharagni (digestive capacity) is also responsible for complexion [Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 15/3], hence such diet should be consumed which establishes a healthy jatharagni. Importance of diet in imparting good complexion is mentioned.[Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/349] [Cha. Sa. [[Sutra Sthana|Sutra Sthana]] 27/3]. The food that is consumed is digested by jatharagni. This digestion produces nourishment to the [[Dhatu|dhatus (tissues)]] of the [[Sharira|body]]. Healthy tissues are responsible for maintenance of healthy skin, thus indicating role of jatharagni in varna.

== Ojas & varna ==

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Ojas is the essence of the body tissues (dhatus) [Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/24]. As healthy state of all dhatu keeps the skin healthy.Thusone of the functions of ojas is to maintain varna.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/25] The qualitative deterioration (ojavyapat) causes impairment of complexion.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/29]

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Ojas is the essence of the [[Dhatu|body tissues (dhatus)]] [Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/24]. As healthy state of all dhatu keeps the skin healthy.Thusone of the functions of ojas is to maintain varna.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/25] The qualitative deterioration (ojavyapat) causes impairment of complexion.[Su. Sa. [[Sutra Sthana|Sutra Sthana]] 15/29]

== Varna as an atmaja bhava ==

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== Importance of concept ==

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=== Importance in diagnosis & prognosis of disease: ===

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=== Importance in diagnosis & prognosis of [[Vyadhi|disease]]: ===

The natural complexion indicates a state of health or natural physiological processes inside the [[Sharira|body]]. Sudden spontaneous change in natural complexion may be due to some pathology. Sudden drastic change in natural complexion may also indicate death in near future. Apart from discussing the natural complexion, some of the abnormal complexions like blue, grey, coppery, green and albino (extremely white)are described. [Cha. Sa. [[Indriya Sthana|IndriyaSthana]] 1/9] Example, cyanotic complexion is observed in severe right ventricular hypertrophic cardiomyopathy.<ref name="ref6" /> The abnormalities includeif half of the [[Sharira|body]] has natural complexion and the other have abnormal complexion, and both of them are evenly demarcated by a line.These normal and abnormal complexions may simultaneously appear in left and right sides, front and back sides, upper and lower parts or internal and external parts of the [[Sharira|body]]. Natural and abnormal complexions simultaneously appearing in face or other parts of the [[Sharira|body]], are the morbid signs indicating imminent death.[Cha. Sa. [[Indriya Sthana|IndriyaSthana]] 1/10] For example, amelanotic melanomas presenting as red skin lesions are often lethal.<ref name="ref7" />

=== Clinical diagnosis based on varna: ===

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Some diseases often have an impact on varna. Thus varna can be used as one of the diagnostic criterias for identification of diseases. Examples are as follows:

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Some [[Vyadhi|diseases]] often have an impact on varna. Thus varna can be used as one of the diagnostic criterias for identification of [[Vyadhi|diseases]]. Examples are as follows:

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* Pandu (anaemia); Pale colour. [Cha. Sa. ChikitsaSthana 16/11]

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* Pandu (anaemia); Pale colour. [Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 16/11]

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* Kamla (jaundice): Yellowish [Cha. Sa. ChikitsaSthana 16/35]

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* Kamla (jaundice): Yellowish [Cha. Sa. [[Chikitsa Sthana|ChikitsaSthana]] 16/35]

* Vitiligo: Depigmented patches over skin.

* Albinism: Depigmentation of skin.

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<li style="font-weight:bold">Skin reflectance: These devices are typically pointed at the upper arm or forehead, with the emitted waves then interpreted at various percentages.</li>

<li style="font-weight:bold">Brown Paper Bag Test: The ‘Brown Paper Bag Test’ is a term in African-American oral history used to describe a colourist discriminatory practice within the African-American community in the 20th century, in which an individual's skin tone is compared to the colour of a brown paper bag.</li>

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<li style="font-weight:bold">Tele-spectroradiometers (TSRs) and spectrophotometers (SPs): TSRs are used for measuring colour appearance such as in cosmetic industry for developing skin colour charts and evaluating skin products. SPs are mainly used for diagnosing skin disease symptom, such as erythema and irritation.</li>

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<li style="font-weight:bold">Tele-spectroradiometers (TSRs) and spectrophotometers (SPs): TSRs are used for measuring colour appearance such as in cosmetic industry for developing skin colour charts and evaluating skin products. SPs are mainly used for diagnosing skin [[Vyadhi|disease]] symptom, such as erythema and irritation.</li>

<li style="font-weight:bold">Skintone Pen TP 20:It is a battery-operated probe to determine skin pigmentation (melanin) on a scale from 0-99.</li></ol>

== Current researches ==

<ol style="text-align:justify;"><li style="font-weight:bold">Cosmetic approach of varna in [[Ayurveda|Ayurveda]]<ref name="ref14">Sonam, Meena KS, (2019). Cosmetic Approach of Varna in Ayurveda. International Journal of Research in Medical Sciences and Technology Vol. No. 8, Jul-Dec e-ISSN: 2455-5134, p-ISSN: 2455-9059 555.</ref> The research article discusses the process and principles of varnotpatti (development of varna). Normal varna of an individual has to be considered under two headings: Sahaja (the colour and complexion, which is since birth, falls under this category) and Jatottara (due to exposure external factors like sun-exposure, hot atmosphere, humidity, pollution, etc sometimes the complexion of an individual becomes different from the one he was born with). </li>

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<li style="font-weight:bold">Understanding the concept of varnotpattiin [[Ayurveda|Ayurveda]]<ref name="ref15">Bhaurao, D.S. (2017). Understanding the Concept of Varnotpatti in Ayurveda. International Journal of Innovative Research in Medical Science, 2(09), 1341 to 1345. https://doi.org/10.23958/ijirms/vol02-i09/20</ref> The research article discusses the factors contributing in the formation of varna in foetal life (role of mahabhuta, semen, procreative factors, state of mind of mother, food and behaviour of mother, topography, race and genetics) and factors contributing in the process of varnotpatti after birth (role of digestive capability, food and method of consumption of food, body tissues, biological humors, metabolic wastes, ojas and age).</li>

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<li style="font-weight:bold">Understanding the concept of varnotpattiin [[Ayurveda|Ayurveda]]<ref name="ref15">Bhaurao, D.S. (2017). Understanding the Concept of Varnotpatti in Ayurveda. International Journal of Innovative Research in Medical Science, 2(09), 1341 to 1345. https://doi.org/10.23958/ijirms/vol02-i09/20</ref> The research article discusses the factors contributing in the formation of varna in foetal life (role of [[Pancha mahabhuta|mahabhuta]], semen, procreative factors, state of mind of mother, food and behaviour of mother, topography, race and genetics) and factors contributing in the process of varnotpatti after birth (role of digestive capability, food and method of consumption of food, body tissues, biological humors, metabolic wastes, ojas and age).</li>

<li style="font-weight:bold">The concept of varna an Ayurvedic prospective<ref name="ref16">Brahma S, Sharma MK (2018). The Concept of Varna An Ayurvedic Prospective. World Journal of Pharmaceutical Research, Volume 7, Issue 18, 450-460. ISSN 2277–7105.</ref> Apart from other factors, this article also discusses the relation of varna with stress,ACTH and adrenocortical secretion. Almost any type of physical and mental stress can lead within minutes to greatly enhanced secretions of ACTH and consequently cortisol as well (> 20 folds). When ACTH is secreted by the anterior pituitary gland, several other hormones like melanocytes stimulating hormone (MSH), lipotropin, and endotrophin that have similar chemical structures are secreted simultaneously. The reason for this is the gene transcribed to form the RNA molecule that causes ACTH synthesis initially causes the formation of a considerably larger protein, a preprohormone called proopiomelanocortin (POMC), which is the precursor of ACTH and several other peptides, including MSH, beta-lipotropin, beta-endorphin and few others. Under normal condition, most of these hormones are not secreted in enough quantity by the pituitary. But when the rate of secretion of ACTH is high, some of the POMC derived hormones may also be increased. The POMC gene is actively transcribed in several tissues, like cells of dermis and lymphoid tissue. In melanocytes, located abundantly between the dermis and epidermis of the skin, MSH stimulates formation of black pigment melanin and disperses into the epidermis. On the other hand within minutes the entire sequence leads to large quantities of cortisol in blood. It circulates through blood to reach skin cells. It slows down the skin cells and make cells take long time to get to the surface and peel off. Therefore, the dead skin cells enhance, resulting lifeless and looks of the skin. Along with that overstress situation moves the blood away from the skin, and a little amount of blood moves around, which turns again insufficient supply of oxygen through the skin. In this process, the skin doesn’t get the required nourishment, which results in pale and dull skin.</li></ol>

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