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{{#seo:

{{#seo:

|title=Vajikarana Chikitsa Adhyaya

|title=Vajikarana Chikitsa Adhyaya

|titlemode=append

|titlemode=append

|keywords=Vajikarana, Shukra, Vrishya, libido, sexual dysfunctions, infertility, healthy progeny,Aphrodisiac, Ayurveda, charak samhita, Indian system of medicine.

|keywords=[[Vajikarana]], Shukra, Vrishya, libido, sexual dysfunctions, infertility, healthy progeny,Aphrodisiac, Ayurveda, charak samhita, Indian system of medicine, increase libido in ayurveda, sexual vigor, sexual vigour, sexual power, stamina

|description=Chikitsa Sthana Chapter 2. Aphrodisiac therapy, virility and treatment of sexual dysfunctions

|description=Chikitsa Sthana Chapter 2. Aphrodisiac therapy, virility and treatment of sexual dysfunctions

|image=http://www.carakasamhitaonline.com/mediawiki-1.32.1/resources/assets/ogimgs.jpg

|image=http://www.carakasamhitaonline.com/resources/assets/ogimgs.jpg

|image_alt=charak samhita

|image_alt=charak samhita

|type=article

|type=article

}}

}}

{{Infobox

{{Infobox

|title = Vajikarana Chikitsa

|title = [[Vajikarana]] Chikitsa

|label1 = Section/Chapter

|label1 = Section/Chapter

|data1 = [[Chikitsa Sthana]] Chapter 2

|data1 = [[Chikitsa Sthana]] Chapter 2

|label7 = Reviewer  

|label7 = Reviewer  

|data7  = Dixit U., Prasad B.S.

|data7  = Dixit U., Prasad B.S.

|label8 = Editor

|label8 = Editors

|data8  = Dixit U.

|data8  = Dixit U., [[Yogesh Deole|Deole Y.S.]], [[Gopal Basisht|Basisht G.]]

|label9 = Date of publication  

|label9 = Year of publication  

|data9 = December 17, 2018

|data9 = 2020

|label10 = DOI

|label10 = Publisher

|data10  =  

|data10 = [[Charak Samhita Research, Training and Skill Development Centre]]

|header3 =  

|label11 = DOI

|data11 = [https://doi.org/10.47468/CSNE.2020.e01.s06.003 10.47468/CSNE.2020.e01.s06.003]

 

<big>'''Abstract'''</big>

<big>'''Abstract'''</big>

<div style="text-align:justify;">''Vajikarana'' is a branch of [[Ayurveda]] which is intended to increase virility, improve quality of germinal cells as well treatment of various sexual dysfunctions. In this chapter code of conduct related to sex, dietary regime, qualities of normal sperm, factors affecting virility, qualities of sexual partner, role of mind in infertility, aphrodisiac and therapeutic formulations etc. are described. Simple and easy to prepare formulations are described in the chapter. Though these are described for males but we can apply same principles and formulations to female also for more preponderant effect. ''Vajikarana'' is generally misinterpreted as sexology. This myth is broken in this chapter by mentioning other effects of wider applicability and can be used for improving progeny and creating better world. The chapter is restricted to principles, regime and formulations. Aetiological factors, pathology of sexual dysfunctions and other aspects are mentioned in other chapters of this text.

<p style="text-align:justify;">[[Vajikarana]] is a branch of [[Ayurveda]] which is intended to increase virility, improve quality of germinal cells as well treatment of various sexual dysfunctions. In this chapter code of conduct related to sex, dietary regime, qualities of normal sperm, factors affecting virility, qualities of sexual partner, role of mind in infertility, aphrodisiac and therapeutic formulations etc. are described. Simple and easy to prepare formulations are described in the chapter. Though these are described for males but we can apply same principles and formulations to female also for more preponderant effect. [[Vajikarana]] is generally misinterpreted as sexology. This myth is broken in this chapter by mentioning other effects of wider applicability and can be used for improving progeny and creating better world. The chapter is restricted to principles, regime and formulations. Aetiological factors, pathology of sexual dysfunctions and other aspects are mentioned in other chapters of this text. </p>

 

== Introduction ==

== Introduction ==

Sexual relationships are among the most important social and biological relationships in human life. India played a significant role in the history of sex, right from writing of the first literature that treated sexual intercourse as a science. Since ancient times, India pioneered the use of sexual education through art and literature. This subject was not considered taboo in [[Ayurveda]] and it was included as separate branch ''vajikarana'' in which various aspects related to sexuality are scientifically dealt. If we see the literal meaning of ''vajikarana'', we find that this word is made up of two words – ''Vaji'' and ''Karana''. ''Vaji'' refers to horse and karana refers to power. So, ''vajikarana'' can be said to be a modality by which one can perform sexual activity for long time and frequently like a horse. But the effect of this branch is much more and helps to achieve good physique, potency, strength and complexion; it revitalizes the reproductive power; helps in getting healthy and good progeny; resolves various sexual dysfunctions like erectile dysfunction, infertility, premature ejaculations etc. Hence it can be said that subject is concerned with aphrodisiacs, virility and improving health of progeny.

Sexual relationships are among the most important social and biological relationships in human life. India played a significant role in the history of sex, right from writing of the first literature that treated sexual intercourse as a science. Since ancient times, India pioneered the use of sexual education through art and literature. This subject was not considered taboo in [[Ayurveda]] and it was included as separate branch [[Vajikarana]] in which various aspects related to sexuality are scientifically dealt. If we see the literal meaning of [[Vajikarana]], we find that this word is made up of two words – ''Vaji'' and ''Karana''. ''Vaji'' refers to horse and karana refers to power. So, [[Vajikarana]] can be said to be a modality by which one can perform sexual activity for long time and frequently like a horse. But the effect of this branch is much more and helps to achieve good physique, potency, strength and complexion; it revitalizes the reproductive power; helps in getting healthy and good progeny; resolves various sexual dysfunctions like erectile dysfunction, infertility, premature ejaculations etc. Hence it can be said that subject is concerned with aphrodisiacs, virility and improving health of progeny.

Literature related to ''vajikarana'' is present in all the three great treatises which show that this subject was considered paramount for betterment of humans. In [[Charak Samhita]] it is placed before describing treatment of various diseases and in ''Sushruta Samhita'', it is described after discussion of disease treatment. In ''Ashtanga'' it is mentioned in ''Uttara Sthana'' and is last chapter of this text. The order of placement depends upon basic theme of a text. Charak has given prime importance to promotion and preservation of health, whereas Sushruta and Vagbhata emphasized upon the treatment of diseases. This shows with time, Ayurvedic concept of promotion and prevention of health became less important in comparison to disease management.  

Literature related to [[Vajikarana]] is present in all the three great treatises which show that this subject was considered paramount for betterment of humans. In [[Charak Samhita]] it is placed before describing treatment of various diseases and in ''Sushruta Samhita'', it is described after discussion of disease treatment. In ''Ashtanga'' it is mentioned in ''Uttara Sthana'' and is last chapter of this text. The order of placement depends upon basic theme of a text. Charak has given prime importance to promotion and preservation of health, whereas Sushruta and Vagbhata emphasized upon the treatment of diseases. This shows with time, Ayurvedic concept of promotion and prevention of health became less important in comparison to disease management.  

[[Vajikarana]] is divided in four sections - ''Samyoga Sharamooliya'', ''Asikti Kshirika, Mashaparnabhritiya'' and ''Pumana Jata Baladika''. If we analyze the name of these sub-sections we will find that out of four, name of three sections (''Samyoga Sharamooliya, Asikti Kshirika, Mashaparnabhritiya'') are based on the first formulation described. Last section is named to give emphasis on their effect. The name of four sub-sections or ''pada'', itself suggests that in [[Vajikarana]] chapter, accentuation is given more to formulations. On analyzing these formulations one interesting fact which comes out is that out of 50 formulations mentioned very few can be considered as therapeutic preparations. Only four ''gutika'' or ''vati'' (tablets) are mentioned whereas seven ''mamsarasa'' (meat soup), ten types of milk preparations, four types of eggs, six types of ''pupalika, audana, payasa, rasala'' (different rice and milk preparations), etc. are given. Most of them are common dietary preparations included in normal diet and can be easily prepared. While stating difference in ''rasayana'' and ''vajikarana'', it is stated that ''vajikarana'' should be administered regularly to an individual.  

[[Vajikarana]] is divided in four sections - ''Samyoga Sharamooliya'', ''Asikti Kshirika, Mashaparnabhritiya'' and ''Pumana Jata Baladika''. If we analyze the name of these sub-sections we will find that out of four, name of three sections (''Samyoga Sharamooliya, Asikti Kshirika, Mashaparnabhritiya'') are based on the first formulation described. Last section is named to give emphasis on their effect. The name of four sub-sections or ''pada'', itself suggests that in [[Vajikarana]] chapter, accentuation is given more to formulations. On analyzing these formulations one interesting fact which comes out is that out of 50 formulations mentioned very few can be considered as therapeutic preparations. Only four ''gutika'' or ''vati'' (tablets) are mentioned whereas seven ''mamsarasa'' (meat soup), ten types of milk preparations, four types of eggs, six types of ''pupalika, audana, payasa, rasala'' (different rice and milk preparations), etc. are given. Most of them are common dietary preparations included in normal diet and can be easily prepared. While stating difference in ''[[rasayana]]'' and [[Vajikarana]], it is stated that [[Vajikarana]] should be administered regularly to an individual.  

[[Ayurveda]] considers ''brahmacharya'' as one of the three ''upastambha'' or pillars of life. It refers to a certain code of conduct related to sexual life. It is said that sexual activity should be neither practiced as complete celibacy nor excessive indulgence should be done as both will have detrimental effect on body as well as mind. It is recommended that the person below 17 years of age and more than 70 years of age should not consume ''vajikarana'' preparations. These preparations have to be consumed by ''Jitendriya Purusha'' or man who has control on his senses and desires. If ''vajikarana'' preparations are consumed by a man who has lost control over his senses and desire, he may prove harmful to society. Excessive coitus leads to ''shosha'' or loss of ''dhatus'' and suppression of sexual desire leads to impotency. Rules regarding coitus frequency, time, pattern changes due to seasonal variation, pre and post coitus preparations etc. are described at different places in ''Samhita''. Before administration of ''vajikarana'' therapy purification should be done so that vitiated ''doshas'' and toxins are removed from the body and blocked channels are opened. This leads to increased bio-availability of ''vajikarana'' drugs for beneficial results. ''Vajikarana'' treatment benefits include increased sexual performance, improving health of future progeny as well as treatment of many sexual disorders like infertility, erectile dysfunction and premature ejaculation.  

[[Ayurveda]] considers ''brahmacharya'' as one of the three ''upastambha'' or pillars of life. It refers to a certain code of conduct related to sexual life. It is said that sexual activity should be neither practiced as complete celibacy nor excessive indulgence should be done as both will have detrimental effect on body as well as mind. It is recommended that the person below 17 years of age and more than 70 years of age should not consume [[Vajikarana]] preparations. These preparations have to be consumed by ''Jitendriya Purusha'' or man who has control on his senses and desires. If [[Vajikarana]] preparations are consumed by a man who has lost control over his senses and desire, he may prove harmful to society. Excessive coitus leads to ''shosha'' or loss of ''[[dhatu]]s'' and suppression of sexual desire leads to impotency. Rules regarding coitus frequency, time, pattern changes due to seasonal variation, pre and post coitus preparations etc. are described at different places in ''Samhita''. Before administration of [[Vajikarana]] therapy purification should be done so that vitiated ''[[dosha]]s'' and toxins are removed from the body and blocked channels are opened. This leads to increased bio-availability of [[Vajikarana]] drugs for beneficial results. [[Vajikarana]] treatment benefits include increased sexual performance, improving health of future progeny as well as treatment of many sexual disorders like infertility, erectile dysfunction and premature ejaculation.  

[[Ayurveda]] has given immense importance to women in relation to sexual activity. Woman has been referred as ''kshetra'' or medium in which seed (or sperm) is implanted and fetal growth and development takes place. To get healthy progeny, woman should have certain qualities like she must be from different clan, physically and mentally salubrious and she should be pure (she should have taken post menstrual bath etc.). Such claims are still valid as it is seen that marriages in blood relatives or in same clan have more preponderance of genetic disorders. Chance of having healthy progeny is influenced by the mental state of partners. In ancient times, society was male dominant and females were not given equivalent status & rights like their male counterparts. At many places, social beliefs and rituals prevalent at that time has affected Ayurvedic literature. In ''vajikarana'' also most of the descriptions are related to males only. Rules, formulations, code of conduct etc. mentioned apply to females also and so ''vajikarana'' principles and formulations should not be restricted to males only and should be administered to females also.

[[Ayurveda]] has given immense importance to women in relation to sexual activity. Woman has been referred as ''kshetra'' or medium in which seed (or sperm) is implanted and fetal growth and development takes place. To get healthy progeny, woman should have certain qualities like she must be from different clan, physically and mentally salubrious and she should be pure (she should have taken post menstrual bath etc.). Such claims are still valid as it is seen that marriages in blood relatives or in same clan have more preponderance of genetic disorders. Chance of having healthy progeny is influenced by the mental state of partners. In ancient times, society was male dominant and females were not given equivalent status & rights like their male counterparts. At many places, social beliefs and rituals prevalent at that time has affected Ayurvedic literature. In [[Vajikarana]] also most of the descriptions are related to males only. Rules, formulations, code of conduct etc. mentioned apply to females also and so [[Vajikarana]] principles and formulations should not be restricted to males only and should be administered to females also.

It can be stated that ''vajikarana'' is the special branch of [[Ayurveda]] which improves the reproductive system and enhances sexual function. It deals with aphrodisiacs, virility and improving health of progeny. The principles described can provide solution to increasing sexual dysfunctions and declining fecundity. Scientific research is needed in the field of ''vajikarana'' therapies.

It can be stated that [[Vajikarana]] is the special branch of [[Ayurveda]] which improves the reproductive system and enhances sexual function. It deals with aphrodisiacs, virility and improving health of progeny. The principles described can provide solution to increasing sexual dysfunctions and declining fecundity. Scientific research is needed in the field of [[Vajikarana]] therapies.

</div>

</div>

Now we shall expound the first quarter section entitled ''Samyoga Sharamooliya'' on the virilification. Thus, said Lord Atreya. [1-2]

Now we shall expound the first quarter section entitled ''Samyoga Sharamooliya'' on the virilification. Thus, said Lord Atreya. [1-2]

==== Importance of ''vajikarana'' and woman as the best for virilification ====

==== Importance of [[Vajikarana]] and woman as the best for virilification ====

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The person, who is healthy and desirous of a child, should enter in to sexual intercourse with a woman who belongs to a different clan, who is free from diseases, who is sexually excited, cheerful and who has taken her post menstrual purifacatory bath. [8-15]

The person, who is healthy and desirous of a child, should enter in to sexual intercourse with a woman who belongs to a different clan, who is free from diseases, who is sexually excited, cheerful and who has taken her post menstrual purifacatory bath. [8-15]

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==== Disregard of childless person and benefits of ''vajikarana'' ====

==== Disregard of childless person and benefits of [[Vajikarana]] ====

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==== Various preparations for improving virility ====

==== Various preparations for improving virility ====

==== ''Brimhani Gutika'' ====

==== Brimhani Gutika ====

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Three ''palas'' (1 ''pala''=approx.40 gram) of each of the roots of ''shara'' and sugarcane, giant sugarcane, ''ikshubaalika'', ''shatavari'', ''payasya, vidari, kantakari, jeevanti, jeevaka, meda, beera, rishbhaka, bala, ridhi, gokshura, raasna, atmagupta,'' and ''punarnava'' should be mixed with one ''adhaka'' of freshly collected ''masha'' and boiled in one ''drona'' of water till one fourth remains. After that, the paste of ''madhuka, draksha, falgu, pippali, atmagupta, madhuka, kharhura, shatavari, vidari, amalaki'' and the juice of sugarcane should be separately added and one ''adhaka'' of ghee and one ''drona'' of milk should be mixed to it. After boiling this should be filtered and one ''prastha'' of each of sugar and the powder of ''tugakshiri'', four ''palas'' of ''pippali'', one ''pala'' of ''maricha'', half ''pala'' each of the powder of ''twak, ela'' and saffron and two ''kudava'' of honey should be added. Now, semi-solid pills of size of one ''pala'' each in quantity should be prepared. This preparation is highly virilific, nourishing and promoter of strength. On administration of these pills, the person gets stallion like vigor in sexual intercourse. (Formulation: ''Brimhani Ghutika'') [24-32]

Three pala (1 pala=approx 40 gram) of each of the roots of [[shara]] and [[ikshu]] (sugarcane), giant sugarcane, [[ikshuvaalika]], [[shatavari]], [[payasya]], [[vidari]], [[kantakari]], [[jeevanti]], [[jeevaka]], [[meda]], [[veera]], [[rishbhaka]], [[bala]], [[riddhi]], [[gokshura]], [[raasna]], [[atmagupta]], and [[punarnava]] should be mixed with one ''adhaka'' of freshly collected ''masha'' and boiled in one ''drona'' of water till one fourth remains. After that, the paste of ''madhuka, draksha, falgu, pippali, atmagupta, madhuka, kharhura, shatavari, vidari, amalaki'' and the juice of sugarcane should be separately added and one ''adhaka'' of ghee and one ''drona'' of milk should be mixed to it. After boiling this should be filtered and one ''prastha'' of each of sugar and the powder of ''tugakshiri'', four ''palas'' of ''pippali'', one ''pala'' of ''maricha'', half ''pala'' each of the powder of ''twak, ela'' and saffron and two ''kudava'' of honey should be added. Now, semi-solid pills of size of one ''pala'' each in quantity should be prepared. This preparation is highly virilific, nourishing and promoter of strength. On administration of these pills, the person gets stallion like vigor in sexual intercourse. (Formulation: ''Brimhani Ghutika'') [24-32]

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==== ''Vajikarana Ghritam'' ====

 

==== Vajikarana Ghritam ====

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Decoction of one ''adhaka'' each of freshly collected ''masha'', seeds of ''atmagupta, jeevaka, rishbhaka, veera, meda, riddhi, shatavari, madhuka'' and ''ashwagandha'' should be prepared and one ''prastha'' of cow’s ghee, ten ''prastha'' of milk, one ''prastha'' of each of juice of ''vidari'' and sugarcane should be added. After that four ''palas'' of each of sugar ''tugakshiri'', and honey and one ''pala'' of ''pippali'' should be added to it. By taking one ''pala'' of this medicated ghee, the man should take food, if he wishes to have an inexhaustible store of semen and great phallic strength. (Formulation: ''Vajikarana Ghrita'') [33-38]

Decoction of one ''adhaka'' each of freshly collected ''masha'', seeds of ''atmagupta, jeevaka, rishbhaka, veera, meda, riddhi, shatavari, madhuka'' and ''ashwagandha'' should be prepared and one ''prastha'' of cow’s ghee, ten ''prastha'' of milk, one ''prastha'' of each of juice of ''vidari'' and sugarcane should be added. After that four ''palas'' of each of sugar ''tugakshiri'', and honey and one ''pala'' of ''pippali'' should be added to it. By taking one ''pala'' of this medicated ghee, the man should take food, if he wishes to have an inexhaustible store of semen and great phallic strength. (Formulation: ''Vajikarana Ghrita'') [33-38]

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==== ''Vajikarana Pinda Rasa'' ====

==== ''Vajikarana Pinda Rasa'' ====

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Now we shall expound the third section "Mashaparnabhritiya" on the virilification. Thus said Lord Atreya. [1-2]

Now we shall expound the third section "Mashaparnabhritiya" on the virilification. Thus said Lord Atreya. [1-2]

==== Specific cow’s milk for ''vajikarana'' ====

==== Specific cow’s milk for [[Vajikarana]] ====

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The semen gets diminished by old age, worry, anxiety, diseases, overexertion, fasting and excessive sexual indulgence. By consumption, fear, suspicion and grief, by seeing the deformities in woman, by non excitation of the woman, absence of passionate determination, by abstention from sex and just after full sexual enjoyment, a man is rendered incapable of mating with a woman. This depends on strength of the body and mind.[36-45]

The semen gets diminished by old age, worry, anxiety, diseases, overexertion, fasting and excessive sexual indulgence. By consumption, fear, suspicion and grief, by seeing the deformities in woman, by non excitation of the woman, absence of passionate determination, by abstention from sex and just after full sexual enjoyment, a man is rendered incapable of mating with a woman. This depends on strength of the body and mind.[36-45]

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==== Description of ''Shukra'' ====

==== Description of ''[[Shukra]]'' ====

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As the juice exists in the sugarcane, ghee in the whole curd, and oil exists in whole part of the sesame seed, in the same way, semen pervades in the entire body which has the sensation of touch.  

As the juice exists in the sugarcane, ghee in the whole curd, and oil exists in whole part of the sesame seed, in the same way, semen pervades in the entire body which has the sensation of touch.  

The semen trickles down from its site during copulation between man and woman because of sex act, passionate attachment, and physical pressure, as water comes out of a wet cloth when squeezed. The semen is ejaculated from the body as a result of these eight factors- excitement, excessive desire, fluidity, viscosity, heaviness, atomicity and the tendency to flow out and the speedy motion of ''vata''. The un-manifested soul which takes different forms in this world, manifests itself in the form of semen.[46-49]

The semen trickles down from its site during copulation between man and woman because of sex act, passionate attachment, and physical pressure, as water comes out of a wet cloth when squeezed. The semen is ejaculated from the body as a result of these eight factors- excitement, excessive desire, fluidity, viscosity, heaviness, atomicity and the tendency to flow out and the speedy motion of ''[[vata]]''. The un-manifested soul which takes different forms in this world, manifests itself in the form of semen.[46-49]

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==== Characteristics of ''Shukra'' ====

==== Characteristics of ''[[Shukra]]'' ====

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The semen which is thick, sweet, unctuous, without any putrid smell, heavy, viscid, white in color, and abundant in quantity, invariably helps in procreation. This is undoubtful about the semen.[50]

The semen which is thick, sweet, unctuous, without any putrid smell, heavy, viscid, white in color, and abundant in quantity, invariably helps in procreation. This is undoubtful about the semen.[50]

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==== ''Vajikarana'' ====

==== [[Vajikarana]] ====

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##Similar pharmacological function of drugs.  

##Similar pharmacological function of drugs.  

#The male and female partners shall be physically and psychologically able to have pleasant coitus.  

#The male and female partners shall be physically and psychologically able to have pleasant coitus.  

*''Vajikarana'' drugs besides helping get good progeny and pleasure is useful in living healthy and long life.

*[[Vajikarana]] drugs besides helping get good progeny and pleasure is useful in living healthy and long life.

*For copulation, the ''shukra'' should possess qualities such as thickness, sweetness, unctuousness, without any putrid smell, heavyness, viscidity, white in colour, and abundant in quantity. This invariably helps in procreation.

*For copulation, the ''[[shukra]]'' should possess qualities such as thickness, sweetness, unctuousness, without any putrid smell, heavyness, viscidity, white in colour, and abundant in quantity. This invariably helps in procreation.

*Mind plays a great role in ''vajikarana''. It is important to have a pleasant mind for proper sexual satisfaction. All those items which lead to pleasure increase virility.  

*Mind plays a great role in [[Vajikarana]]. It is important to have a pleasant mind for proper sexual satisfaction. All those items which lead to pleasure increase virility.  

*Sexual act should not be done before age16 and after age 70.

*Sexual act should not be done before age16 and after age 70.

== Vidhi Vimarsha (Applied Inferences ) ==

== Vidhi Vimarsha (Applied Inferences ) ==

''Rasayana'' and ''vajikarana'' therapies have common aim to provide positive health and prevention of diseases by increasing vigor of healthy person and so, [[Vajikarana]] is described just after [[Rasayana]] chapter. Health scientists are showing great interest in screening classical ''rasayana'' drugs for their antioxidant activity and research reveals good results. Studies on ''amalaki rasayana'' <ref>Dwivedi V, Anandan EM, Mony RS, Muraleedharan TS, Valiathan MS, Mutsuddi M, et al. In vivo effects of traditional Ayurvedic formulations in Drosophila melanogaster relate with therapeutic applications. PLoS One. 2012;7:e37113.</ref> shows increased longevity and on Drosophila melanogaster <ref> Fontana L, Partridge L, Longo VD. Extending healthy life span – From yeast to humans. Science. 2010;328:321–6.</ref> there is reduced oxidative damage to extend lifespan. Many drugs are described as ''rasayanas'' and ''vajikara'' both. Reactive oxygen species (ROS) has deteriorating effect on sperm. This has been increasing due to changing lifestyle and exposure to environmental pollution. Spermatozoa normally produce ROS in a normal physiological process. The amount of ROS produced is to be carefully controlled. Imbalance between the generation and scavenging of ROS may lead to damage to DNA or other important structures. Spermatozoa lack cytoplasmic defensive enzymes, such as catalase, glutathione peroxidase, which are involved in the protection of most cell types from ROS induced peroxidative damage. Large amounts of unsaturated fatty acids are observed in plasma membranes of spermatozoa, those are particularly vulnerable to free radical attack.<ref>Jones R and Mann T (1973) Lipid peroxidation in spermatozoa. Proc R Soc Lond B Biol Sci 184,103–107.</ref> The subfertile men have higher concentrations of ROS in seminal plasma, whereas an inverse correlation exists between ROS concentration and motility.<ref>Carlsen E, Giwercman A, Keiding N, Skakkebaek NE, Review Evidence for decreasing quality of semen during past 50 years. BMJ. 1992 Sep 12; 305(6854):609-13</ref> Many ''rasayanas'' act as antioxidants, so they can also be used to enhance sperm quality and quantity. Thus, mutual correlation and common mode of action justifies description of ''vajikarana'' just after ''rasayana'' therapy.

''[[Rasayana]]'' and [[Vajikarana]] therapies have common aim to provide positive health and prevention of diseases by increasing vigor of healthy person and so, [[Vajikarana]] is described just after [[Rasayana]] chapter. Health scientists are showing great interest in screening classical ''[[rasayana]]'' drugs for their antioxidant activity and research reveals good results. Studies on ''amalaki rasayana'' <ref>Dwivedi V, Anandan EM, Mony RS, Muraleedharan TS, Valiathan MS, Mutsuddi M, et al. In vivo effects of traditional Ayurvedic formulations in Drosophila melanogaster relate with therapeutic applications. PLoS One. 2012;7:e37113.</ref> shows increased longevity and on Drosophila melanogaster <ref> Fontana L, Partridge L, Longo VD. Extending healthy life span – From yeast to humans. Science. 2010;328:321–6.</ref> there is reduced oxidative damage to extend lifespan. Many drugs are described as ''[[rasayana]]s'' and ''vajikara'' both. Reactive oxygen species (ROS) has deteriorating effect on sperm. This has been increasing due to changing lifestyle and exposure to environmental pollution. Spermatozoa normally produce ROS in a normal physiological process. The amount of ROS produced is to be carefully controlled. Imbalance between the generation and scavenging of ROS may lead to damage to DNA or other important structures. Spermatozoa lack cytoplasmic defensive enzymes, such as catalase, glutathione peroxidase, which are involved in the protection of most cell types from ROS induced peroxidative damage. Large amounts of unsaturated fatty acids are observed in plasma membranes of spermatozoa, those are particularly vulnerable to free radical attack.<ref>Jones R and Mann T (1973) Lipid peroxidation in spermatozoa. Proc R Soc Lond B Biol Sci 184,103–107.</ref> The subfertile men have higher concentrations of ROS in seminal plasma, whereas an inverse correlation exists between ROS concentration and motility.<ref>Carlsen E, Giwercman A, Keiding N, Skakkebaek NE, Review Evidence for decreasing quality of semen during past 50 years. BMJ. 1992 Sep 12; 305(6854):609-13</ref> Many ''[[rasayana]]s'' act as antioxidants, so they can also be used to enhance sperm quality and quantity. Thus, mutual correlation and common mode of action justifies description of [[Vajikarana]] just after ''[[rasayana]]'' therapy.

For many years, decline in human semen quality and fertility rates has been a concern.<ref>MacLeod J, Heim L M. Characteristics and variations in semen specimens in 100 normal young men. Journal of Urology. 1945;54:474–482.</ref> Environmental and occupational pollutants, changes in lifestyles, exposure to toxic agents, and changes in dietary habits are observed among the most commonly cited factors associated with these declines.<ref>Tielemans E, Burdorf A, te Velde ER, Weber RF, van Kooij RJ, Veulemans H, Heederik DJ, Occupationally related exposures and reduced semen quality: a case-control study, Fertil Steril. 1999 Apr; 71(4):690-6.</ref> The environmental and lifestyle factors causing subfertility shall be targeted for curative or preventive measures. Environmental stress causes increase in the number of free radicals (i.e., hydrogen peroxide [H2O2] and reactive oxygen species [ROS] that cause apoptosis in the spermatogenic cell.<ref>Wang X, Sharma RK, Sikka SC. Oxidative stress is associated with increased apoptosis leading to spermatoozoa DNA damage in patients with male factor infertility. Fertil Steril. 2003;80:531–5.</ref> Chronic or severe stress leads to anovulation and amenorrhea in women <ref>Barnea, E. R., and Tal, J. Stress-r elated reproductive failure. J. In Vitro Fertil. Embryo Transfer 8: 15-23 (1991).</ref> and to decrease in sperm count, motility, and morphology in men.<ref>McGrady, A. V. Effects of psychological stress on male reproduction: a review. Arch. Androl. 131: 1-10 (1984).</ref> Smoking,<ref>Goverde HJ, Dekker HS, Janssen HJ, Bastiaans BA, Rolland R, Zielhuis GA.,Semen quality and frequency of smoking and alcohol consumption--an explorative study. Int J Fertil Menopausal Stud. 1995 May-Jun;40(3):135-8.</ref> alcohol,<ref>Joo KJ, Kwon YW, Myung SC, Kim TH, The effects of smoking and alcohol intake on sperm quality: light and transmission electron microscopy findings. J Int Med Res. 2012;40(6):2327-35.</ref> caffeine,<ref>Vine MF, Setzer RW Jr, Everson RB, Wyrobek AJ, Human sperm morphometry and smoking, caffeine, and alcohol consumption. Reprod Toxicol. 1997 Mar-Jun;11(2-3):179-84.</ref> pesticides, air pollution,<ref>Jurewicz J, Hanke W, Radwan M, Bonde JP, Environmental factors and semen quality.Int J Occup Med Environ Health. 2009;22(4):305-29.</ref> bisphenol A,<ref>Akingbemi BT, Sottas CM, Koulova AI, Klinefelter GR, Hardy MP. Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells. Endocrinology. 2004;145:592–603</ref> diseases like hypertension, diabetes mellitus, obesity, cardio-vascular disease are related to deterioration of reproductive health<ref>Sunil Kumar, Archana Kumari, Shiva, Murarka, Lifestyle factors in deteriorating male reproductive health, Indian Journal of Experimental Biology, Vol 47, August 2009, pp.615-624.</ref> by affecting sperm quality.  

For many years, decline in human semen quality and fertility rates has been a concern.<ref>MacLeod J, Heim L M. Characteristics and variations in semen specimens in 100 normal young men. Journal of Urology. 1945;54:474–482.</ref> Environmental and occupational pollutants, changes in lifestyles, exposure to toxic agents, and changes in dietary habits are observed among the most commonly cited factors associated with these declines.<ref>Tielemans E, Burdorf A, te Velde ER, Weber RF, van Kooij RJ, Veulemans H, Heederik DJ, Occupationally related exposures and reduced semen quality: a case-control study, Fertil Steril. 1999 Apr; 71(4):690-6.</ref> The environmental and lifestyle factors causing subfertility shall be targeted for curative or preventive measures. Environmental stress causes increase in the number of free radicals (i.e., hydrogen peroxide [H2O2] and reactive oxygen species [ROS] that cause apoptosis in the spermatogenic cell.<ref>Wang X, Sharma RK, Sikka SC. Oxidative stress is associated with increased apoptosis leading to spermatoozoa DNA damage in patients with male factor infertility. Fertil Steril. 2003;80:531–5.</ref> Chronic or severe stress leads to anovulation and amenorrhea in women <ref>Barnea, E. R., and Tal, J. Stress-r elated reproductive failure. J. In Vitro Fertil. Embryo Transfer 8: 15-23 (1991).</ref> and to decrease in sperm count, motility, and morphology in men.<ref>McGrady, A. V. Effects of psychological stress on male reproduction: a review. Arch. Androl. 131: 1-10 (1984).</ref> Smoking,<ref>Goverde HJ, Dekker HS, Janssen HJ, Bastiaans BA, Rolland R, Zielhuis GA.,Semen quality and frequency of smoking and alcohol consumption--an explorative study. Int J Fertil Menopausal Stud. 1995 May-Jun;40(3):135-8.</ref> alcohol,<ref>Joo KJ, Kwon YW, Myung SC, Kim TH, The effects of smoking and alcohol intake on sperm quality: light and transmission electron microscopy findings. J Int Med Res. 2012;40(6):2327-35.</ref> caffeine,<ref>Vine MF, Setzer RW Jr, Everson RB, Wyrobek AJ, Human sperm morphometry and smoking, caffeine, and alcohol consumption. Reprod Toxicol. 1997 Mar-Jun;11(2-3):179-84.</ref> pesticides, air pollution,<ref>Jurewicz J, Hanke W, Radwan M, Bonde JP, Environmental factors and semen quality.Int J Occup Med Environ Health. 2009;22(4):305-29.</ref> bisphenol A,<ref>Akingbemi BT, Sottas CM, Koulova AI, Klinefelter GR, Hardy MP. Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells. Endocrinology. 2004;145:592–603</ref> diseases like hypertension, diabetes mellitus, obesity, cardio-vascular disease are related to deterioration of reproductive health<ref>Sunil Kumar, Archana Kumari, Shiva, Murarka, Lifestyle factors in deteriorating male reproductive health, Indian Journal of Experimental Biology, Vol 47, August 2009, pp.615-624.</ref> by affecting sperm quality.  

=== Role of diet in ''vajikarana'' ===

=== Role of diet in [[Vajikarana]] ===

Nutrition status is also a major cause of sub-fertility. Sexual dysfunction due to malnutrition can be easily overcome. Nutrition is important for DNA synthesis leading to development of spermatozoa and oocytes. Diet also provides exogenous antioxidants (vitamins C and E).  Dietary formulations mentioned are perfect amalgamation of energy and nutrients required for production and maturation of sperm.   

Nutrition status is also a major cause of sub-fertility. Sexual dysfunction due to malnutrition can be easily overcome. Nutrition is important for DNA synthesis leading to development of spermatozoa and oocytes. Diet also provides exogenous antioxidants (vitamins C and E).  Dietary formulations mentioned are perfect amalgamation of energy and nutrients required for production and maturation of sperm.   

In [[Ayurveda]], ''ahara'' or diet has been considered to be a form of medicine (''bhaishajya'') and the role of diet is not limited to nutrition only. Properly planned diet can be used for prevention as well as treatment of the diseases. ''Shukra'' is one of the seven ''dhatus'' and is formed by successive evolution of ''dhatus'' starting from ''rasa dhatu'' and diet forms the substrate [Cha.Sa. [[Chikitsa Sthana]] 15/16]. So, ''ahara'' is one important factor on which quality of ''dhatu'' depends.  

In [[Ayurveda]], ''ahara'' or diet has been considered to be a form of medicine (''bhaishajya'') and the role of diet is not limited to nutrition only. Properly planned diet can be used for prevention as well as treatment of the diseases. ''[[Shukra]]'' is one of the seven ''[[dhatu]]s'' and is formed by successive evolution of ''[[dhatu]]s'' starting from ''[[rasa dhatu]]'' and diet forms the substrate [Cha.Sa. [[Chikitsa Sthana]] 15/16]. So, ''ahara'' is one important factor on which quality of ''[[dhatu]]'' depends.  

Various simple dietary preparations which can increase quantity as well as quality of sperm are mentioned.  The substance acts in various modes in the body, one of those is the principle of ''dravya samanya'' (similarity in substance) i.e. consumption of food item similar to body tissues increase them due to similar constitution. Keeping this fact in mind semen of different animals has been used with fat. ''Snigdha dravya'' (unctuous substances) increase semen by similar properties. However, this mode of therapy may not have individual acceptance or practical in current period so principle of ''guna samanya'' (''dravya'' with similar properties) may be used.

Various simple dietary preparations which can increase quantity as well as quality of sperm are mentioned.  The substance acts in various modes in the body, one of those is the principle of ''dravya samanya'' (similarity in substance) i.e. consumption of food item similar to body tissues increase them due to similar constitution. Keeping this fact in mind semen of different animals has been used with fat. ''Snigdha dravya'' (unctuous substances) increase semen by similar properties. However, this mode of therapy may not have individual acceptance or practical in current period so principle of ''[[guna]] samanya'' (''dravya'' with similar properties) may be used.

==== Role of milk and dairy products ====

==== Role of milk and dairy products ====

==== Feeding of animal affects quality of milk ====

==== Feeding of animal affects quality of milk ====

Milk composition can be altered by the feeding regime of cow. Content of several fatty acids such as c9, t11-CLA and the ratio between omega-6 and omega-3 fatty acids are affected by the amount of grass and supplemental feeds (concentrate) in the diet. Milk content of several vitamins and minerals are also influenced by the cow's diet.<ref>Anna Haug, Arne T Hostmark, and Odd M Harstad Bovine milk in human nutrition – a review, Lipids Health Dis. 2007; 6: 25.</ref> In a study it was found that concentrations of micro-components like CLA, and to a lesser extent EPA and DHA, can be significantly enhanced through the use of diet formulation and nutritional management of dairy cows.<ref>Lock AL, Bauman DE, Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health, Lipids, 2004 Dec;39(12):1197-206</ref> In another study effect of diet and cooling interactions on milk composition were studied in cows. So, it can be said that diet definitely affects milk composition and in turn effects are also modulated. If cow is fed with ''masha'' then the qualities of milk will increase and thus such milk is said to be good aphrodisiac that have more beneficial effects on sperm quality. Masha itself has properties of increasing ''shukra'' as it has ''snigdha'' and ''madhura'' qualities.

Milk composition can be altered by the feeding regime of cow. Content of several fatty acids such as c9, t11-CLA and the ratio between omega-6 and omega-3 fatty acids are affected by the amount of grass and supplemental feeds (concentrate) in the diet. Milk content of several vitamins and minerals are also influenced by the cow's diet.<ref>Anna Haug, Arne T Hostmark, and Odd M Harstad Bovine milk in human nutrition – a review, Lipids Health Dis. 2007; 6: 25.</ref> In a study it was found that concentrations of micro-components like CLA, and to a lesser extent EPA and DHA, can be significantly enhanced through the use of diet formulation and nutritional management of dairy cows.<ref>Lock AL, Bauman DE, Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health, Lipids, 2004 Dec;39(12):1197-206</ref> In another study effect of diet and cooling interactions on milk composition were studied in cows. So, it can be said that diet definitely affects milk composition and in turn effects are also modulated. If cow is fed with ''masha'' then the qualities of milk will increase and thus such milk is said to be good aphrodisiac that have more beneficial effects on sperm quality. Masha itself has properties of increasing ''[[shukra]]'' as it has ''snigdha'' and ''madhura'' qualities.

According to [[Ayurveda]], cow milk is better than other milk. Beneficial role of cow’s milk has been established by some recent researches. A study unambiguously clarified at the cellular level that cow's milk increased the activities of human PPARalpha, PPARdelta, and RXRalpha. The nuclear peroxisome proliferator-activated receptors (PPAR) have been shown to play crucial roles in regulating energy homeostasis including lipid and carbohydrate metabolism, inflammatory responses, and cell proliferation, differentiation, and survival because PPAR agonists have the potential to prevent or ameliorate diseases such as hyperlipidemia, diabetes, atherosclerosis, and obesity.<ref>Suhara W, Koide H, Okuzawa T, Hayashi D, Hashimoto T, Kojo H., Cow's milk increases the activities of human nuclear receptors peroxisome proliferator-activated receptors alpha and delta and retinoid X receptor alpha involved in the regulation of energy homeostasis, obesity, and inflammation, J Dairy Sci. 2009 Sep;92(9):4180-7</ref> Milk is itself regarded as ''Sadyo Shukrakara'' (means instant aphrodisiac) in [[Ayurveda]] as it increases sperm quality soon after the consumption.

According to [[Ayurveda]], cow milk is better than other milk. Beneficial role of cow’s milk has been established by some recent researches. A study unambiguously clarified at the cellular level that cow's milk increased the activities of human PPARalpha, PPARdelta, and RXRalpha. The nuclear peroxisome proliferator-activated receptors (PPAR) have been shown to play crucial roles in regulating energy homeostasis including lipid and carbohydrate metabolism, inflammatory responses, and cell proliferation, differentiation, and survival because PPAR agonists have the potential to prevent or ameliorate diseases such as hyperlipidemia, diabetes, atherosclerosis, and obesity.<ref>Suhara W, Koide H, Okuzawa T, Hayashi D, Hashimoto T, Kojo H., Cow's milk increases the activities of human nuclear receptors peroxisome proliferator-activated receptors alpha and delta and retinoid X receptor alpha involved in the regulation of energy homeostasis, obesity, and inflammation, J Dairy Sci. 2009 Sep;92(9):4180-7</ref> Milk is itself regarded as ''Sadyo Shukrakara'' (means instant aphrodisiac) in [[Ayurveda]] as it increases sperm quality soon after the consumption.

==== Rice and its preparation with milk ====

==== Rice and its preparation with milk ====

''Shashitika'' rice is ''snigdha, madhura'' and ''sheeta'' and so by Ayurvedic principle of ''guna samanya'' (similar properties) it helps in improving semen quality.<ref>Chakrapani, Charak Samhita of Charak with [[Ayurveda]] Dipika commentary, Sutrasthana, 5/3, Rastriya Sanskrit Sansthana, Delhi, 2006.</ref> ''Balya'' and ''brimhaniya'' drugs are added to rice for increasing strength of patient. ''Masha, shali, shashtika, godhuma'' provide combination of both carbohydrate and protein. It can be taken with milk and meat juice which again adds nutritive value. As digestive power varies with persons, dose fixation should be done individually after assessment of ''agni''.

''Shashtika'' rice is ''snigdha, madhura'' and ''sheeta'' and so by Ayurvedic principle of ''[[guna]] samanya'' (similar properties) it helps in improving semen quality.<ref>Chakrapani, Charak, Sutra sthana, chap 5 Matrasheetia Adhyaya Verse 3, Rastriya Sanskrit Sansthana, Delhi, 2006.</ref> ''Balya'' and ''brimhaniya'' drugs are added to rice for increasing strength of patient. ''Masha, shali, shashtika, godhuma'' provide combination of both carbohydrate and protein. It can be taken with milk and meat juice which again adds nutritive value. As digestive power varies with persons, dose fixation should be done individually after assessment of ''agni''.

''Payasa'' is dietary preparation which is popular as sweet dish in India. It is prepared from combination of milk and rice. It has property to increase sperm quality. If made from various aphrodisiac drugs its effect is much more. ''Payasa'' is included in normal diet regime so it can be easy aphrodisiac formulation by changing contents of ''Payasa''.

''Payasa'' is dietary preparation which is popular as sweet dish in India. It is prepared from combination of milk and rice. It has property to increase sperm quality. If made from various aphrodisiac drugs its effect is much more. ''Payasa'' is included in normal diet regime so it can be easy aphrodisiac formulation by changing contents of ''Payasa''.

=== Ghee ===

=== Ghee ===

Clarified butter (''ghrita'' or ghee) is used as aphrodisiac because it is considered good for ''rasa, shukra'' and ''ojas'' ([[Charak Samhita]] [[Sutra Sthana]] 13/14). Intake of regular ghrita and milk is said to be best ''rasayana'' in ''Agrya Prakrana'' by Charak. Ghee is used as processing media that carries the therapeutic properties of herbs to all the body's tissues. Proper metabolism of drug is crucial in obtaining the maximum benefit. The lipophilic action of ghee facilitates transportation to a target organ and final delivery inside the cell, since the cell membrane also contains lipid. The effect of  herb increases when it is used with ghee as compared to powder or tablet form.<ref> Illingworth D, Patil GR, Tamime AY. Anhydrous milk fat manufacture and fractionation. In: Tamime AY, editor. Dairy Fats and Related Products. Chichester, West Sussex: Wiley-Blackwell; 2009.</ref> ''Rasala'' has been said to be ''balya'' and ''shukrala'' (Bhavaprakasha Purva Khanda-12/124-127).  

Clarified butter (''ghrita'' or ghee) is used as aphrodisiac because it is considered good for ''[[rasa]], [[shukra]]'' and ''[[ojas]]'' [Cha. Sa.[[Sutra Sthana]] 13/14]. Intake of regular ghrita and milk is said to be best ''[[rasayana]]'' in ''Agrya Prakrana'' by Charak. Ghee is used as processing media that carries the therapeutic properties of herbs to all the body's tissues. Proper metabolism of drug is crucial in obtaining the maximum benefit. The lipophilic action of ghee facilitates transportation to a target organ and final delivery inside the cell, since the cell membrane also contains lipid. The effect of  herb increases when it is used with ghee as compared to powder or tablet form.<ref> Illingworth D, Patil GR, Tamime AY. Anhydrous milk fat manufacture and fractionation. In: Tamime AY, editor. Dairy Fats and Related Products. Chichester, West Sussex: Wiley-Blackwell; 2009.</ref> ''Rasala'' has been said to be ''balya'' and ''shukrala''<ref>Bhavamishra. Bhavaprakasha -Volume I.Purva Khanda Chapter 12 Verse 124-127 Translated from Sanskrit by K.R. Srikantha Murthy. 1st ed. Varanasi: Krishnadas academy;2000.pp.- </ref>

''Pupalika'' is a dietary preparation which increases strength and sexual power. When prepared with potent aphrodisiac drugs as mentioned above its efficacy increases many fold. Such preparation can be easily prepared and can be used as food supplement.

''Pupalika'' is a dietary preparation which increases strength and sexual power. When prepared with potent aphrodisiac drugs as mentioned above its efficacy increases many fold. Such preparation can be easily prepared and can be used as food supplement.

Egg increases virility as they provide indispensable nutrients needed for sperm formation. Pork and chicken meat has been used in some formulations. For vegetarians, a diet rich in protein with high nutritive value can be used.  

Egg increases virility as they provide indispensable nutrients needed for sperm formation. Pork and chicken meat has been used in some formulations. For vegetarians, a diet rich in protein with high nutritive value can be used.  

Fish has ''snigdha, madhura, vrimhaniya, balya'' and ''vrishya'' properties. ''Shaphari'' is a kind of small fish. ''Rohita'' is best among different varieties of fish. On basis of ''guna'', fish helps in improving sperm quality. Fish has various important constituents that are not synthesized by humans. Seafood, such as fish, crustacean and mollu

Fish has ''snigdha, madhura, vrimhaniya, balya'' and ''vrishya'' properties. ''Shaphari'' is a kind of small fish. ''Rohita'' is best among different varieties of fish. On basis of [[guna]], fish helps in improving sperm quality. Fish has various important constituents that are not synthesized by humans. Seafood, such as fish, crustacean and molluscan shellfish, and echinoderms, provides in the edible part (e. g., filet, abdominal muscle) many nutritional components beneficial for the human diet like n-3 polyunsaturated long chain fatty acids (PUFAs), namely eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), essential elements such as selenium and iodine, high potassium and low sodium concentrations, and the vitamins D, A, E, and B-12, as well as taurine (2-aminoethanesulfonic acid) among others. Omega-3 fatty acids are major components of neuronal, retinal, and myocardial membranes. Its protein is highly digestible due to low connective tissue content, and cholesterol content is also low in fish. Lean fish species are extremely low in fat content (<1 %), while fatty species are extremely rich in PUFAs.<ref>Oehlenschläger J Seafood: nutritional benefits and risk aspects, Int J Vitam Nutr Res. 2012 Jun;82(3):168-76. doi: 10.1024/0300-9831/a000108</ref> Many of these are required for proper functioning of reproductive system of human. So, fish may help in improving sperm quality.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

==References==

==References==