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<p style="text-align:justify;">Understanding the physiology of suppression of natural urges (vegarodhajanya) symptoms and analyzing them as a pathology of various diseases related to apana vayu (one of the five subtypes of vata situated in the pelvic region). As, seen in clinical practice many a times diseases reoccur after giving proper treatment. Also, in such case causative factors (nidana) of vitiation of apana vayu (one of the five subtypes of vata situated in the pelvic region) is to be analyzed properly for better result. Among the fourteen adharaneeya vega (suppression of natural urges), apana vayu (one of the five subtypes of vata situated in the pelvic region) vega (urge) is most commonly suppressed which leads to vitiation of vata dosha in the pelvic region). Adharaneeya vega (suppression of natural urges) is a reflex mechanism and it is a nervous activity. Nerve supply to gastrointestinal tract is in the form of sympathetic, parasympathetic, enteric nervous system (ENS) and gastrointestinal reflexes. The ENS is to be referred as second brain, it uses serotonin to communicate with the central nervous system. This “brain gut axis’ helps us in understanding how psychological and social stress might cause digestive problems. ENS is closely related to central nervous system (CNS). As mentioned, blindness (‘andhya’) is one of the udavarta janya vikara (diseases caused by udavarta) which is difficult to understand how eyes are related to apana vayu (one of the five subtypes of vata situated in the pelvic region). In an article named ‘Gut microbes linked to eye diseases’ observations have been made by the researchers regarding the possible connection between the gut microbes and the eye diseases. Apana vayu (one of the five subtypes of vata situated in the pelvic region) is mostly parasympathetic in action and its action is related to urine (mutra), stool (purisha), flatus (adhovata) and seminal discharge (shukra vega). Obstruction in passing flatus (apana vayu rodha) invariably affects the prana vayu (one type of the five subtypes of vata situated in upward body or head) among and other vital points in body (marma sthana) like herat (hrudya), brain (shiras), and urinary bladder (basti).</p>

<p style="text-align:justify;">Understanding the physiology of suppression of natural urges (vegarodhajanya) symptoms and analyzing them as a pathology of various diseases related to apana vayu (one of the five subtypes of vata situated in the pelvic region). As, seen in clinical practice many a times diseases reoccur after giving proper treatment. Also, in such case causative factors (nidana) of vitiation of apana vayu (one of the five subtypes of vata situated in the pelvic region) is to be analyzed properly for better result. Among the fourteen adharaneeya vega (suppression of natural urges), apana vayu (one of the five subtypes of vata situated in the pelvic region) vega (urge) is most commonly suppressed which leads to vitiation of vata dosha in the pelvic region). Adharaneeya vega (suppression of natural urges) is a reflex mechanism and it is a nervous activity. Nerve supply to gastrointestinal tract is in the form of sympathetic, parasympathetic, enteric nervous system (ENS) and gastrointestinal reflexes. The ENS is to be referred as second brain, it uses serotonin to communicate with the central nervous system. This “brain gut axis’ helps us in understanding how psychological and social stress might cause digestive problems. ENS is closely related to central nervous system (CNS). As mentioned, blindness (‘andhya’) is one of the udavarta janya vikara (diseases caused by udavarta) which is difficult to understand how eyes are related to apana vayu (one of the five subtypes of vata situated in the pelvic region). In an article named ‘Gut microbes linked to eye diseases’ observations have been made by the researchers regarding the possible connection between the gut microbes and the eye diseases. Apana vayu (one of the five subtypes of vata situated in the pelvic region) is mostly parasympathetic in action and its action is related to urine (mutra), stool (purisha), flatus (adhovata) and seminal discharge (shukra vega). Obstruction in passing flatus (apana vayu rodha) invariably affects the prana vayu (one type of the five subtypes of vata situated in upward body or head) among and other vital points in body (marma sthana) like herat (hrudya), brain (shiras), and urinary bladder (basti).</p>

<p style="text-align:justify;">3) Nidra vegadharana (suppression of sleep) leads to vitiation of vata dosha. Vata controls the functions of mind (mana). Stress is mainly due to mental and physical stimuli which cause disturbances in the internal biological equilibrium. Disturbed and interrupted sleep is very common in the IT professionals due to their work culture. Here, nidra vegadharana (suppression of urge of sleep) acts as a stress stimulus which causes impairment in both sharirika (biological elements vata, pitta and kapha) and manasika (psychological constitution like raja and tama) dosha which causes further loss of sleep (nidranasha). Udavarta affects mind and leads to abnormalities in mental functions similar to mental stress. Hence it is important to avoid nidra vegadharana (suppression of urge of sleep) to prevent further kriyakala i.e., stage of progression of disease leading to stress and other mental disorders. </p>

<p style="text-align:justify;">3) Nidra vegadharana (suppression of sleep) leads to vitiation of vata dosha. Vata controls the functions of mind (mana). Stress is mainly due to mental and physical stimuli which cause disturbances in the internal biological equilibrium. Disturbed and interrupted sleep is very common in the IT professionals due to their work culture. Here, nidra vegadharana (suppression of urge of sleep) acts as a stress stimulus which causes impairment in both sharirika (biological elements vata, pitta and kapha) and manasika (psychological constitution like raja and tama) dosha which causes further loss of sleep (nidranasha). Udavarta affects mind and leads to abnormalities in mental functions similar to mental stress. Hence it is important to avoid nidra vegadharana (suppression of urge of sleep) to prevent further kriyakala i.e., stage of progression of disease leading to stress and other mental disorders. </p>

===Thesis on udavarta===

===Thesis on udavarta===

  <p style="text-align:justify;">In this study total 74 patients have been enrolled which were divided in two groups randomly. The selected drug for clinical trial in group A was Yavanikadi vati (tablet) which contains haritaki (Terminalia chebula), yavani (Trachyspermum ammi), hingu (Ferula foetida), sauvarchala (black salt), yavakshara (alkali prepared from barley) and saindhava (rock salt). The powder of these raw drugs was given 3 times trituration (bhavana) of these raw drugs was given 3 times trituration (bhavana) of lemon juice (nimbu swarasa) to prepare tablet. In group B, Shankha vati (tablet) was taken for control group, which contains purified mercury (shuddha parada) and purified sulphur (shuddha gandhaka). In the group A 31 patients were given Yavanikadi vati in tablet form 1 gm B.D.  in two divided doses (1 tablet = 500 mg.) daily, after food for 28 days with water whereas, in Group B total 30 patients were given Shankha Vati. The dose, duration, time of administration and anupana (co-administers with medicine) is same as group A. Comparison of the therapies showed that overall better results as observed in group A as compared to group B which stands closely parallel to group A. </p>

  <p style="text-align:justify;">In this study total 74 patients have been enrolled which were divided in two groups randomly. The selected drug for clinical trial in group A was Yavanikadi vati (tablet) which contains haritaki (Terminalia chebula), yavani (Trachyspermum ammi), hingu (Ferula foetida), sauvarchala (black salt), yavakshara (alkali prepared from barley) and saindhava (rock salt). The powder of these raw drugs was given 3 times trituration (bhavana) of these raw drugs was given 3 times trituration (bhavana) of lemon juice (nimbu swarasa) to prepare tablet. In group B, Shankha vati (tablet) was taken for control group, which contains purified mercury (shuddha parada) and purified sulphur (shuddha gandhaka). In the group A 31 patients were given Yavanikadi vati in tablet form 1 gm B.D.  in two divided doses (1 tablet = 500 mg.) daily, after food for 28 days with water whereas, in Group B total 30 patients were given Shankha Vati. The dose, duration, time of administration and anupana (co-administers with medicine) is same as group A. Comparison of the therapies showed that overall better results as observed in group A as compared to group B which stands closely parallel to group A. </p>