Changes

#The quality and specific characteristics observed in urine are biomarkers in diagnosis and assessment of ''prameha''.

#The quality and specific characteristics observed in urine are biomarkers in diagnosis and assessment of ''prameha''.

=== Vidhi Vimarsha ===

=== ''Vidhi Vimarsha'' ===

==== The process of onset of disease ====

==== The process of onset of disease ====

Nidana, dosha, and dushya are the inherent factors involved in the pathogenesis of diseases. In addition to these inherent factors, the host also has antibodies and disease resisting factors in him. If the resisting factors are weak and kala, or temporal influences (seasonal variations, age), are strong enough for the inherent causes of the disease, then the disease will be severe with complications and rapid progression. If all the four factors (i.e., nidana, dosha, dushya, and kala) are not strong enough then any of the following manifestations may occur:  

''Nidana, dosha'', and ''dushya'' are the inherent factors involved in the pathogenesis of diseases. In addition to these inherent factors, the host also has antibodies and disease resisting factors in him. If the resisting factors are weak and ''kala'', or temporal influences (seasonal variations, age), are strong enough for the inherent causes of the disease, then the disease will be severe with complications and rapid progression. If all the four factors (i.e., ''nidana, dosha, dushya,'' and ''kala'') are not strong enough then any of the following manifestations may occur:  

1.    No disease

#No disease

2.    Delayed onset  

#Delayed onset  

3.    Mild  

#Mild  

4.    A few signs and symptoms present.  

#A few signs and symptoms present.  

In this chapter, the importance of exogenous (disease causative agents/pathogens), endogenous (deranged body defense mechanism) factors and tissue response in the development of the disease is emphasized. The disease appears either when the exogenous factor (pathogen) is strong enough to overcome the defense mechanism of the body or when the tissue response to exogenous factors or adaptive responses to foreign agents is deranged.

In this chapter, the importance of exogenous (disease causative agents/pathogens), endogenous (deranged body defense mechanism) factors and tissue response in the development of the disease is emphasized. The disease appears either when the exogenous factor (pathogen) is strong enough to overcome the defense mechanism of the body or when the tissue response to exogenous factors or adaptive responses to foreign agents is deranged.

==== The etymology of prameha ====

==== The etymology of ''prameha'' ====

In Sanskrit, the word mih (from which meha is derived) denotes water, to wet, and to emit semen. Regarding the above explanation, we can easily postulate that the disease prameha resulted because of an excessive excretion of something (ati-pravrittija). Prameha comprises of all those diseases that cause clinical abnormalities in urine due to derangement of metabolism at the level of tissues (dhatvagnimandya).  

In Sanskrit, the word ''mih'' (from which ''meha'' is derived) denotes water, to wet, and to emit semen. Regarding the above explanation, we can easily postulate that the disease ''prameha'' resulted because of an excessive excretion of something (''ati-pravrittija''). ''Prameha'' comprises of all those diseases that cause clinical abnormalities in urine due to derangement of metabolism at the level of tissues (''dhatvagnimandya'').  

==== The scope of prameha ====

==== The scope of prameha ====

                                         carbohydrate and

                                         carbohydrate and

                                         fatty acid metabolism

                                         fatty acid metabolism

                                           Hyperinsulinemia

                                           Hyperinsulinemia

 

=== Future Scope for Research ===

=== Future Scope for Research ===

1. Assessment criteria for the classification of various types of Prameha based on both physical as well as laboratory parameters.

1. Assessment criteria for the classification of various types of Prameha based on both physical as well as laboratory parameters.