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===Abnormal states===
 
===Abnormal states===
 
The increase or decrease in quality and/or quantity of mamsa dhatu can lead to various abnormal conditions. The states can be assessed by following clinical features.  
 
The increase or decrease in quality and/or quantity of mamsa dhatu can lead to various abnormal conditions. The states can be assessed by following clinical features.  
Symptoms of mamsa kshaya
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{| class="wikitable"
(decrease of mamsa dhatu)* Symptoms of mamsa vriddhi (increase in mamsa dhatu)**
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|-
Decrease in circumference and skin fold thickness ofhips, neck and belly due to loss of bulk of muscles Increase in circumference and skin fold thickness of buttocks, cheeks, lips, penis, thighs, arms and calves
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! Symptoms of ''mamsa kshaya''(decrease of mamsa dhatu)* !!Symptoms of ''mamsa vriddhi'' (increase in mamsa dhatu)**
wasting of buttocks, cheeks, penis, thighs, chest, axillae, calves heaviness of the body
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|-
Dryness Extra muscular growth or Hypertrophied musculature  
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|Decrease in circumference and skin fold thickness of hips, neck and belly due to loss of bulk of muscles || Increase in circumference and skin fold thickness of buttocks, cheeks, lips, penis, thighs, arms and calves
pricking pain
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|-
debility of the body
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|wasting of buttocks, cheeks, penis, thighs, chest, axillae, calves || heaviness of the body
Fatigue
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|-
loss of tone of arteries
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| Dryness || Extra muscular growth or Hypertrophied musculature  
Hypotonia in vessels specially in arterial wall just due to having thick muscular coat in it as compared to veins and capillaries
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|-
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|pricking pain ||--
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|-
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| debility of the body ||-
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|-
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| Fatigue |--
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|-
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| loss of tone of arteries ||--
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|-
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|Hypotonia in vessels specially in arterial wall just due to having thick muscular coat in it as compared to veins and capillaries | --
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|}
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*[Cha. Sa. Sutra  Sthana 17/65], [Su. Sam. Sutra Sthana 15/9]
 
*[Cha. Sa. Sutra  Sthana 17/65], [Su. Sam. Sutra Sthana 15/9]
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**[Su. Sam. Sutra Sthana 15/24]
 
**[Su. Sam. Sutra Sthana 15/24]
• Mamsa kshaya (diminution of muscle tissue) is generally considered as a bad prognostic feature. [Su. Sam. Sutra Sthana 32/5],[Su. Sam. Sutra Sthana 33/5,18,25].
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• Mamsa vruddhi can be easily classified into two classes as – Hypertrophy & Heaviness. Hypertrophy can also be understood in terms of – Arbuda (tumorous growth or myoma); Granthi (nodular growth) – Lump, Cyst, Polypous growth; and Adhimamsa (excess fleshy growth layer by layer)
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''Mamsa kshaya'' (diminution of muscle tissue) is generally considered as a bad prognostic feature. [Su. Sam. Sutra Sthana 32/5],[Su. Sam. Sutra Sthana 33/5,18,25].
Clinical features of vitiation of mamsavaha srotas:  
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• Adhimamsa (granuloma or polyps), arbuda (tumorous growth or myoma), kila (piles, skin tags, warts), galashaluka (uvulitis), galashundika (tonsillitis), putimamsa (gangrene), alaji (boils), ganda (goiter), gandamala (cervical lymphadenitis), and upajihvika (inflammation of epiglottis).[Cha.Sa. Sutra Sthana 28/13-15]
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''Mamsa vruddhi'' can be easily classified into two classes as – Hypertrophy & Heaviness. Hypertrophy can also be understood in terms of – ''arbuda'' (tumorous growth or myoma); ''granthi'' (nodular growth) – Lump, Cyst, Polypous growth; and ''adhimamsa'' (excess fleshy growth layer by layer)
• The symptoms produced due to injury to mamsavaha srotas are shwayathu(edema),mamsashosha(wasting), siragrandhi(aneurism) and death.[ Su.Sa. Sharir Sthana 9/12]
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• Burning sensation inside the body, thirst, unconsciousness, weakness, diarrhea, foul smell from the body and convulsive movements of the limbs are the features manifesting in mamsagata jwara. [Cha. Sa. Chikitsa  Sthana 3/78]
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'''Clinical features of vitiation of ''mamsavaha srotas'':'''
Role of mamsa dhatu as vitiated factor in diseases:
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Mamsa dhatu is involved as the dushya(vitiated tissue) in the pathogenesis of various diseases as listed below:  
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''Adhimamsa'' (granuloma or polyps), ''arbuda'' (tumorous growth or myoma), ''kila'' (piles, skin tags, warts), ''galashaluka'' (uvulitis), ''galashundika'' (tonsillitis), ''putimamsa'' (gangrene), ''alaji'' (boils), ''ganda'' (goiter), ''gandamala'' (cervical lymphadenitis), and ''upajihvika'' (inflammation of epiglottis).[Cha.Sa. Sutra Sthana 28/13-15]
• Avruta madhumeha(diabetes due to obstructive pathogenesis) [Cha. Sa. Sutra  Sthana 17/79],prameha pidaka(diabetic carbuncles) [Cha. Sa. Sutra  Sthana 17/82],  
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• shotha(swelling) [Cha. Sa. Sutra  Sthana 18/7],
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• The symptoms produced due to injury to ''mamsavaha srotas'' are ''shwayathu''(edema),''mamsashosha''(wasting), ''siragrandhi''(aneurism) and death.[ Su.Sa. Sharir Sthana 9/12]
• prameha (obstinate urinary disorders) [Cha. Sa. Nidana  Sthana 4/8],
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• kushtha(skin disorders)[Cha. Sa. Nidana  Sthana 5/3],
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• Burning sensation inside the body, thirst, unconsciousness, weakness, diarrhea, foul smell from the body, and convulsive movements of the limbs are the features manifesting in ''mamsagata jwara''. [Cha. Sa. Chikitsa  Sthana 3/78]
• shosha(wasting diseases)[Cha. Sa. Nidana  Sthana 6/8],
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• granthi(nodule) [Cha. Sa. Chikitsa  Sthana 12/81],
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Role of ''mamsa dhatu'' as vitiated factor in diseases:
• arsha (hemorrhoids)[Cha. Sa. Chikitsa  Sthana 14/5],
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• kamala(jaundice) [Cha. Sa. Chikitsa  Sthana 16/34],
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''Mamsa dhatu'' is involved as the ''dushya''(vitiated tissue) in the pathogenesis of various diseases as listed below:  
• visarpa (erysipelas) [Cha. Sa. Chikitsa  Sthana 21/15],
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• vidradhi(abcess)[Su.Sam. Nidana Sthana 9/4],
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''Avruta madhumeha''(diabetes due to obstructive pathogenesis) [Cha. Sa. Sutra  Sthana 17/79],''prameha pidaka''(diabetic carbuncles) [Cha. Sa. Sutra  Sthana 17/82],
• Tritiyaka jwara  [Cha. Sa. Chikitsa  Sthana 3/66]
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• Mamsakleda(retention of moisture) and mamsadaha (inflammation) are included among the 40 disorders due to pitta. [Cha. Sa. Sutra  Sthana 20/16]
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''shotha''(swelling) [Cha. Sa. Sutra  Sthana 18/7]
• When vitiated vata is located in muscles and fat, it manifests as heaviness of body, pricking pain and as if beaten by a strong rod,severe pain and fatigue. [Cha. Sa. Chikitsa Sthana 28/32]
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• When vata gets occluded by mamsa,it causes hard,discolored boils,swellings, horripilation and tingling. [Cha. Sa. Chikitsa Sthana 28/64]
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''prameha'' (obstinate urinary disorders) [Cha. Sa. Nidana  Sthana 4/8]
• The strava(discharge) from a vrana situated in muscle tissue resemblesghee. It is thick, white and slimy. [Su. Sa. Sutra Sthana 22/8]
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• If a foreign body gets lodged in mamsa, it produces the symptoms like increase of swelling, appearance of new growth in the path of foreign body, intolerance on pressure , sucking pain and formation of pus. [Su. Sa. Sutra Sthana 26/10]
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''kushtha''(skin disorders)[Cha. Sa. Nidana  Sthana 5/3]
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''shosha''(wasting diseases)[Cha. Sa. Nidana  Sthana 6/8]
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''granthi''(nodule) [Cha. Sa. Chikitsa  Sthana 12/81]
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''arsha'' (hemorrhoids)[Cha. Sa. Chikitsa  Sthana 14/5]
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''kamala''(jaundice) [Cha. Sa. Chikitsa  Sthana 16/34]
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''visarpa'' (erysipelas) [Cha. Sa. Chikitsa  Sthana 21/15]
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''vidradhi''(abcess)[Su.Sam. Nidana Sthana 9/4]
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''Tritiyaka jwara'' [Cha. Sa. Chikitsa  Sthana 3/66]
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''Mamsakleda''(retention of moisture) and ''mamsadaha'' (inflammation) are included among the 40 disorders due to pitta. [Cha. Sa. Sutra  Sthana 20/16]
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• When vitiated [[''vata'']] is located in muscles and fat, it manifests as heaviness of body, pricking pain and as if beaten by a strong rod,severe pain and fatigue. [Cha. Sa. Chikitsa Sthana 28/32]
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• When [[vata]] gets occluded by ''mamsa'', it causes hard,discolored boils,swellings, horripilation and tingling. [Cha. Sa. Chikitsa Sthana 28/64]
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• The ''srava''(discharge) from a ''vrana'' situated in muscle tissue resembles ghee. It is thick, white and slimy. [Su. Sa. Sutra Sthana 22/8]
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• If a foreign body gets lodged in ''mamsa'', it produces the symptoms like an increase of swelling, the appearance of new growth in the path of foreign body, intolerance on pressure, sucking pain and formation of pus. [Su. Sa. Sutra Sthana 26/10]
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• Suturing is indicated in non-inflammatory ulcers penetrated upto muscles without any other complications. [Su. Sa. Chikitsa Sthana 1/45]
 
• Suturing is indicated in non-inflammatory ulcers penetrated upto muscles without any other complications. [Su. Sa. Chikitsa Sthana 1/45]
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Prognosis:
 
Prognosis:
• Vrana (ulcer) is easily curable when situated in mamsa. [Cha. Sa. Chikitsa Sthana 25/36]
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• From prognosticaspect, mamsagata jwara is curable. [Cha. Sa. Chikitsa  Sthana 3/83]
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''Vrana'' (ulcer) is easily curable when situated in ''mamsa''. [Cha. Sa. Chikitsa Sthana 25/36]
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• From prognosticaspect, ''mamsagata jwara'' is curable. [Cha. Sa. Chikitsa  Sthana 3/83]
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• In case of fracture, if the inflammation of muscle tissue is noticed, it is difficult to cure. [Su. Sa. Chikitsa Sthana 3/69]
 
• In case of fracture, if the inflammation of muscle tissue is noticed, it is difficult to cure. [Su. Sa. Chikitsa Sthana 3/69]
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• Formation of muscular sprout like structure on the surgical site is considered as a sign of improper surgical management. [Su. Sa. Sutra Sthana 5/15]
 
• Formation of muscular sprout like structure on the surgical site is considered as a sign of improper surgical management. [Su. Sa. Sutra Sthana 5/15]
  
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