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Gentle one (Agnivesha), the abnormal conditions of the stars, the planets, the Moon, the Sun, the wind, the fire and the directions seem to give us the ominous sign that there is going to be a derangement of seasons. As a result of this abnormality, the earth will fail to produce herbs possessing good qualities of ''rasa'' (taste), ''veerya'' (potency), ''vipaka'' (metabolism of diet and drugs), and ''prabhava'' (specific attribute). In consequence of these properties, spread of diseases is certain. Therefore, well before any calamities occur and well before the earth has lost its fertility, collect the medicinal herbs before they lose their ''rasa, veerya, vipaka'' and ''prabhava''. We shall thus, when the occasion arises, make use of the drugs having optimum qualities for the benefit of those who seek us and also those whom we seek to help. There will not be any difficulty in counteracting any ''janapadodhvansa vyadhi'' (disease due to natural calamities or epidemics), if the drugs are properly collected well in advance, processed and administered. [4]
 
Gentle one (Agnivesha), the abnormal conditions of the stars, the planets, the Moon, the Sun, the wind, the fire and the directions seem to give us the ominous sign that there is going to be a derangement of seasons. As a result of this abnormality, the earth will fail to produce herbs possessing good qualities of ''rasa'' (taste), ''veerya'' (potency), ''vipaka'' (metabolism of diet and drugs), and ''prabhava'' (specific attribute). In consequence of these properties, spread of diseases is certain. Therefore, well before any calamities occur and well before the earth has lost its fertility, collect the medicinal herbs before they lose their ''rasa, veerya, vipaka'' and ''prabhava''. We shall thus, when the occasion arises, make use of the drugs having optimum qualities for the benefit of those who seek us and also those whom we seek to help. There will not be any difficulty in counteracting any ''janapadodhvansa vyadhi'' (disease due to natural calamities or epidemics), if the drugs are properly collected well in advance, processed and administered. [4]
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==== Agnivesha’s query ====
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==== Agnivesha’s question ====
    
एवं वादिनं भगवन्तमात्रेयमग्निवेश उवाच-उद्धृतानि खलु भगवन्! भैषज्यानि, सम्यग्विहितानि, सम्यगवचारितानि च; अपि तु खलु जनपदोद्ध्वंसनमेकेनैव व्याधिना युगपदसमानप्रकृत्याहारदेहबलसात्म्यसत्त्ववयसां मनुष्याणां कस्माद्भवतीति||५||  
 
एवं वादिनं भगवन्तमात्रेयमग्निवेश उवाच-उद्धृतानि खलु भगवन्! भैषज्यानि, सम्यग्विहितानि, सम्यगवचारितानि च; अपि तु खलु जनपदोद्ध्वंसनमेकेनैव व्याधिना युगपदसमानप्रकृत्याहारदेहबलसात्म्यसत्त्ववयसां मनुष्याणां कस्माद्भवतीति||५||  

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