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<p style="text-align:justify;">3) Nidra vegadharana (suppression of sleep) leads to vitiation of vata dosha. Vata controls the functions of mind (mana). Stress is mainly due to mental and physical stimuli which cause disturbances in the internal biological equilibrium. Disturbed and interrupted sleep is very common in the IT professionals due to their work culture. Here, nidra vegadharana (suppression of urge of sleep) acts as a stress stimulus which causes impairment in both sharirika (biological elements vata, pitta and kapha) and manasika (psychological constitution like raja and tama) dosha which causes further loss of sleep (nidranasha). Udavarta affects mind and leads to abnormalities in mental functions similar to mental stress. Hence it is important to avoid nidra vegadharana (suppression of urge of sleep) to prevent further kriyakala i.e., stage of progression of disease leading to stress and other mental disorders.<ref>S. Gopakumar, M. A. Shajahan. A Review on Conceptual Relationship between Nidra vegadharana and Manifestation of Stress among IT professionals. International Ayurvedic Medical Journal, ISSN: 2320 5091, April- May 2107, 1(4). </ref> </p>

<p style="text-align:justify;">3) Nidra vegadharana (suppression of sleep) leads to vitiation of vata dosha. Vata controls the functions of mind (mana). Stress is mainly due to mental and physical stimuli which cause disturbances in the internal biological equilibrium. Disturbed and interrupted sleep is very common in the IT professionals due to their work culture. Here, nidra vegadharana (suppression of urge of sleep) acts as a stress stimulus which causes impairment in both sharirika (biological elements vata, pitta and kapha) and manasika (psychological constitution like raja and tama) dosha which causes further loss of sleep (nidranasha). Udavarta affects mind and leads to abnormalities in mental functions similar to mental stress. Hence it is important to avoid nidra vegadharana (suppression of urge of sleep) to prevent further kriyakala i.e., stage of progression of disease leading to stress and other mental disorders.<ref>S. Gopakumar, M. A. Shajahan. A Review on Conceptual Relationship between Nidra vegadharana and Manifestation of Stress among IT professionals. International Ayurvedic Medical Journal, ISSN: 2320 5091, April- May 2107, 1(4). </ref> </p>

<p style="text-align:justify;">4)  In this study total 74 patients have been enrolled which were divided in two groups randomly. The selected drug for clinical trial in group A was Yavanikadi vati (tablet) which contains haritaki (Terminalia chebula), yavani (Trachyspermum ammi), hingu (Ferula foetida), sauvarchala (black salt), yavakshara (alkali prepared from barley) and saindhava (rock salt). The powder of these raw drugs was given 3 times trituration (bhavana) of these raw drugs was given 3 times trituration (bhavana) of lemon juice (nimbu swarasa) to prepare tablet. In group B, Shankha vati (tablet) was taken for control group, which contains purified mercury (shuddha parada) and purified sulphur (shuddha gandhaka). In the group A 31 patients were given Yavanikadi vati in tablet form 1 gm B.D.  in two divided doses (1 tablet = 500 mg.) daily, after food for 28 days with water whereas, in Group B total 30 patients were given Shankha Vati. The dose, duration, time of administration and anupana (co-administers with medicine) is same as group A. Comparison of the therapies showed that overall better results as observed in group A as compared to group B which stands closely parallel to group A.<ref>A clinical study of Udavarta with special reference to Udavarta by Taruna Modhera, Department of Roga Nidana Evam Vikriti Vigyana. Institute for Post Graduate Teaching and Research in Ayurveda. Gujarat Ayurved University, Jamnagar, 2008.</ref> </p>

<p style="text-align:justify;">4)  In this study total 74 patients have been enrolled which were divided in two groups randomly. The selected drug for clinical trial in group A was Yavanikadi vati (tablet) which contains haritaki (Terminalia chebula), yavani (Trachyspermum ammi), hingu (Ferula foetida), sauvarchala (black salt), yavakshara (alkali prepared from barley) and saindhava (rock salt). The powder of these raw drugs was given 3 times trituration (bhavana) of these raw drugs was given 3 times trituration (bhavana) of lemon juice (nimbu swarasa) to prepare tablet. In group B, Shankha vati (tablet) was taken for control group, which contains purified mercury (shuddha parada) and purified sulphur (shuddha gandhaka). In the group A 31 patients were given Yavanikadi vati in tablet form 1 gm B.D.  in two divided doses (1 tablet = 500 mg.) daily, after food for 28 days with water whereas, in Group B total 30 patients were given Shankha Vati. The dose, duration, time of administration and anupana (co-administers with medicine) is same as group A. Comparison of the therapies showed that overall better results as observed in group A as compared to group B which stands closely parallel to group A.<ref>A clinical study of Udavarta with special reference to Udavarta by Taruna Modhera, Department of Roga Nidana Evam Vikriti Vigyana. Institute for Post Graduate Teaching and Research in Ayurveda. Gujarat Ayurved University, Jamnagar, 2008.</ref> </p>