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The signs indicate that a child who is physically or mentally compromised, immune-suppressed, and suffering from severe metabolic or genetic disorders is expected to die early. Symbrachydactly may cause short phalanges. Hypospadias or varicocele may cause enlargement of the genitals. Kyphosis, Lordosis, and spinal or bone disorders may cause back deformation. Visible gums may cause gingivitis and other buccal or respiratory conditions in the future.
 
The signs indicate that a child who is physically or mentally compromised, immune-suppressed, and suffering from severe metabolic or genetic disorders is expected to die early. Symbrachydactly may cause short phalanges. Hypospadias or varicocele may cause enlargement of the genitals. Kyphosis, Lordosis, and spinal or bone disorders may cause back deformation. Visible gums may cause gingivitis and other buccal or respiratory conditions in the future.
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===Quality of Life Scale by World Health Organization (WHO-QOL)===
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The World Health Organization (WHO) has developed a quality of life instrument, the WHOQOL, which captures many subjective aspects of quality of life). The abbreviated version of this scale is known as WHOQOL-BREF. It is applicable for cross-cultural comparisons of quality of life and is available in more than 40 languages. The WHOQOL-BREF is a 26-item instrument consisting of four domains: physical health (7 items), psychological health (6 items), social relationships (3 items), and environmental health (8 items); it also contains QOL and general health items.<ref>WHO. Available from https://www.who.int/publications/i/item/WHOQOL-BREF accessed on 13/08/2022</ref>,<ref>Vahedi S. World Health Organization Quality-of-Life Scale (WHOQOL-BREF): Analyses of Their Item Response Theory Properties Based on the Graded Responses Model. Iran J Psychiatry. 2010 Fall;5(4):140-53. PMID: 22952508; PMCID: PMC3395923.</ref>Currently this scale can be applied in research related to Ayu.
    
==Importance of concept==
 
==Importance of concept==

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