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Fasting therapy results in significant reduction in weight and BMI. In a study conducted on 44 healthy individuals, short term fasting therapy is compared with low calorie diet. Greater reduction in weight and Leptin levels were achieved through fasting than low calorie diet. Increased beta-oxidation is observed during fasting.<ref>Shetty P, Dinesh S, Halappa NG, Rajany T. Comparing the effects of short-term fasting therapy and low-calorie diet on anthropometric and leptin measures among obese or overweight persons: Randomized controlled trial. Ancient Sci Life 2018;37:133-40.</ref>
Fasting therapy results in significant reduction in weight and BMI. In a study conducted on 44 healthy individuals, short term fasting therapy is compared with low calorie diet. Greater reduction in weight and Leptin levels were achieved through fasting than low calorie diet. Increased beta-oxidation is observed during fasting.<ref>Shetty P, Dinesh S, Halappa NG, Rajany T. Comparing the effects of short-term fasting therapy and low-calorie diet on anthropometric and leptin measures among obese or overweight persons: Randomized controlled trial. Ancient Sci Life 2018;37:133-40.</ref>
Average life span is increased by 30% when the rats were maintained on alternate day fasting. Plasma glucose, insulin and leptin levels were low for the rats maintained on fasting. Ketone and adiponectin levels were more. Inflammatory markers were found to be reduced in liver of rats kept on time restricted feeding. The normal decline in muscle mass during ageing is found to be prevented by caloric restriction in mice. Fasting stimulates autophagy in muscles. Cardiovascular stress adaptations were noted in rats kept on alternate day fasting. It also increases brain derived neurotrophic factor which plays a major role in synaptic plasticity and neurogenesis. <ref name=AntonSD/>
Average life span is increased by 30% when the rats were maintained on alternate day fasting. Plasma glucose, insulin and leptin levels were low for the rats maintained on fasting. Ketone and adiponectin levels were more. Inflammatory markers were found to be reduced in liver of rats kept on time restricted feeding. The normal decline in muscle mass during ageing is found to be prevented by caloric restriction in mice. Fasting stimulates autophagy in muscles. Cardiovascular stress adaptations were noted in rats kept on alternate day fasting. It also increases brain derived neurotrophic factor, which plays a major role in synaptic plasticity and neurogenesis. <ref name=AntonSD/>
Fasting is beneficial in metabolic syndrome by decreasing fasting glucose, fasting insulin and insulin resistance. It also reduce the cardiovascular risk factors like total cholesterol, LDL, triglycerides etc. In diabetic patients improved insulin sensitivity and glucose tolerance was reported immediately after a fast. <ref name=AntonSD/>
Fasting is beneficial in metabolic syndrome by decreasing fasting glucose, fasting insulin and insulin resistance. It also reduce the cardiovascular risk factors like total cholesterol, LDL, triglycerides etc. In diabetic patients improved insulin sensitivity and glucose tolerance was reported immediately after a fast. <ref name=AntonSD/>