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#''Prasara''-In this stage aggravated ''vata'' dislodges from its accumulated site and spreads all over the body.
 
#''Prasara''-In this stage aggravated ''vata'' dislodges from its accumulated site and spreads all over the body.
 
#''Sthanasanshraya''- This is the stage in which the ''dosha'' stays at a particular locus and comes in contact with ''dushya''. In case of ''gulma'', the ''mahastrotas'' are the principal loci, with an absence of ''dushya'' in their formation. The vitiated ''vata'' and other ''doshas'' have an affinity towards specific loci such as ''hridaya, nabhi, basti'' etc. to get lodged there. Prodromal symptoms of ''gulma'' such as anorexia, aversion for food, weakness etc. also become apparent at this stage.
 
#''Sthanasanshraya''- This is the stage in which the ''dosha'' stays at a particular locus and comes in contact with ''dushya''. In case of ''gulma'', the ''mahastrotas'' are the principal loci, with an absence of ''dushya'' in their formation. The vitiated ''vata'' and other ''doshas'' have an affinity towards specific loci such as ''hridaya, nabhi, basti'' etc. to get lodged there. Prodromal symptoms of ''gulma'' such as anorexia, aversion for food, weakness etc. also become apparent at this stage.
#Vyakti- Clinical features of different types of gulma manifest at this stage so management can be done depending upon specific dosha characteristics.
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#''Vyakti''- Clinical features of different types of ''gulma'' manifest at this stage so management can be done depending upon specific ''dosha'' characteristics.
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#''Bheda''-When the ''gulma'' is not treated at the fourth and fifth stage, complications like ''bradhna roga'' (inguinal swelling), ''jwara'' (fever), ''vidbheda'' (loose stools/diarrhea), and suppuration (in case of ''pittaja gulma'') occur where surgical intervention could be necessary.  
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f. Bheda-When the gulma is not treated at the fourth and fifth stage, complications like bradhna roga (inguinal swellig), jwara (fever), vidbheda (loose stools/diarrhoea), and suppuration (in case of pittaja gulma ) occur where surgical intervention could be necessary.
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==== Location of ''gulma'' ====
Location of gulma :
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With respect to the adhishthana (location) of gulma, five major sites have been mentioned , including the hridaya, nabhi, basti, and parshwadwaya (flanks). In the context of this chapter, hridaya should be taken as  the upper part of the abdominal cavity rather than the thoracic cage as described in Sharirasthana. Vata gulma most commonly occurs in basti, while pittagulma occurs most commonly in the nabhi region, and kaphagulma in the hridaya and parshwadwaya regions.  The yakrita gulma occurs in the region of hridaya, ashtheela gulma in the region of kukshi (hypogastrium), pleeha gulma in the Madhya (central) region, chandravivardhaka gulma  in the region of basti , and granthi gulma afflicts the region of nabhi.  
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With respect to the ''adhishthana'' (location) of ''gulma'', five major sites have been mentioned , including the ''hridaya, nabhi, basti,'' and ''parshwadwaya'' (flanks). In the context of this chapter, hridaya should be taken as  the upper part of the abdominal cavity rather than the thoracic cage as described in Sharirasthana. Vata gulma most commonly occurs in basti, while pittagulma occurs most commonly in the nabhi region, and kaphagulma in the hridaya and parshwadwaya regions.  The yakrita gulma occurs in the region of hridaya, ashtheela gulma in the region of kukshi (hypogastrium), pleeha gulma in the Madhya (central) region, chandravivardhaka gulma  in the region of basti , and granthi gulma afflicts the region of nabhi.  
 
The pathogenesis of pittaja and kaphaja gulma takes place in amashaya that lies in the region between hridaya and basti.  Thus these two variants of gulma (i.e., pittaja and kaphaja) cannot occur in basti. The five sites of gulma can be mapped to the following anatomical sites of the abdomen:
 
The pathogenesis of pittaja and kaphaja gulma takes place in amashaya that lies in the region between hridaya and basti.  Thus these two variants of gulma (i.e., pittaja and kaphaja) cannot occur in basti. The five sites of gulma can be mapped to the following anatomical sites of the abdomen:
 
Types of gulma Adhisthana Anatomical site Charaka Sushruta Vagbhat Harita
 
Types of gulma Adhisthana Anatomical site Charaka Sushruta Vagbhat Harita