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== ([[Vimana Sthana]] Chapter 6, Chapter on Classification of Diseases) ==

== [[Vimana Sthana]] Chapter 6, Roganika Vimana adhyaya (Chapter on Classification of Diseases) ==

=== Abstract ===

=== Abstract ===

==== Chart 3: Diagrammatic representation of importance of ''Agni'' ====

==== Chart 3: Diagrammatic representation of importance of ''Agni'' ====

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Determination of psychosomatic constitution as well as disease susceptibility of an individual in population through genetic trait is known as ''prakriti''. ''Prakriti'' is a broad term encompasses all the three genotype, phenotype as well as endophenotype.  The concept of prakriti in[https://en.wikipedia.org/wiki/Ayurveda Ayurveda] is related to the bio-characteristic of an individual in healthy state and its vulnerability for particular diseases. According to [https://en.wikipedia.org/wiki/Ayurveda Ayurveda], ''prakriti'' of an individual once determined at the time of fertilization remains unchanged throughout life though it is well influenced by environment. Role of environment in determination of ''prakriti'' during prenatal period is as important as postnatal period. Reviewing the human embryology, it can be postulated that the three primitive germinal layers namely ectoderm, mesoderm and endoderm can be correlated with ''vatika, paittika'' and ''kaphaja'' trait. According to [https://en.wikipedia.org/wiki/Ayurveda Ayurveda] at the time of fertilization the ''doshika prakriti'' is determined by the ''doshika'' predominance of ''shukra'' (sperm) and ''shonita'' (ovum) that represent the fastidious genetic alignment of chromosomes in sperm and ovum and decide the genetic trait of zygote. Robust research is being conducted to study the link between ''prakriti'' and genes.

Determination of psychosomatic constitution as well as disease susceptibility of an individual in population through genetic trait is known as ''prakriti''. ''Prakriti'' is a broad term encompasses all the three genotype, phenotype as well as endophenotype.  The concept of prakriti in Ayurveda is related to the bio-characteristic of an individual in healthy state and its vulnerability for particular diseases. According to Ayurveda, ''prakriti'' of an individual once determined at the time of fertilization remains unchanged throughout life though it is well influenced by environment. Role of environment in determination of ''prakriti'' during prenatal period is as important as postnatal period. Reviewing the human embryology, it can be postulated that the three primitive germinal layers namely ectoderm, mesoderm and endoderm can be correlated with ''vatika, paittika'' and ''kaphaja'' trait. According to Ayurveda at the time of fertilization the ''doshika prakriti'' is determined by the ''doshika'' predominance of ''shukra'' (sperm) and ''shonita'' (ovum) that represent the fastidious genetic alignment of chromosomes in sperm and ovum and decide the genetic trait of zygote. Robust research is being conducted to study the link between ''prakriti'' and genes.

In [[Nidana Sthana]] Chapter 4 ([[Prameha Nidana]]), Acharya says that the development of disease is multifactorial and it depends upon both the virulence of pathogens (''nidana'') as well as host response (''dushya''). Response of the host can be quantified by using ''prakriti'' as a parameter. [13]

In [[Nidana Sthana]] Chapter 4 ([[Prameha Nidana]]), Acharya says that the development of disease is multifactorial and it depends upon both the virulence of pathogens (''nidana'') as well as host response (''dushya''). Response of the host can be quantified by using ''prakriti'' as a parameter. [13]

#Huerta-Yepez, S, Baay-Guzman, G. J., Bebenek, I. G., Hernandez-Pando, R, Vega, M. I., Chi, L, Riedl, M, Diaz-Sanchez, D, Kleerup, E, Tashkin, D. P., Gonzalez, F. J., Bonavida, B, Zeidler, M, and Hankinson,O. (2011) Hypoxia Inducible Factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis. Allergy66 (7),909–18.

#Huerta-Yepez, S, Baay-Guzman, G. J., Bebenek, I. G., Hernandez-Pando, R, Vega, M. I., Chi, L, Riedl, M, Diaz-Sanchez, D, Kleerup, E, Tashkin, D. P., Gonzalez, F. J., Bonavida, B, Zeidler, M, and Hankinson,O. (2011) Hypoxia Inducible Factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis. Allergy66 (7),909–18.

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=== Glossary of Technical Terms ===

=== Glossary ===

#प्रभाव Prabhava - Prognosis

#प्रभाव Prabhava - Prognosis