Changes

Dadima (Punica Granatum): It is madhura, kashaya and amla rasa with ushna veerya and madhur vipaka.  Pomegranates have the potential to thin the blood, increase blood flow to the heart, reduce blood pressure, reduce plaque in the arteries, and reduce bad cholesterol while increasing good cholesterol<ref> Lansky, E.; Shubert, S.; Neeman, I. Pharmacological and therapeutical properties of pomegranate. In Proceedings 1st International Symposium on Pomegranate; Megarejo, P.; Martı´nez, J. J.; </ref>.  Pomegranate seed oil and fermented juice polyphenols tend to inhibit breastcancer cell proliferation, invasion, and promotes apoptosis of breast cancer cells<ref>  N.D., R. Mehta, W. Yu, I. Neeman, T. Livney, A. Amichay, D.Poirier, P. Nicholls, A. Kirby, W. Jiang, R. Mansel, C.Ramachandran, T. Rabi, B. Kaplan, and E. Lansky:Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer.Breast Cancer Research and Treatment 2002; 71(3): 203-17 </ref>.  

Dadima (Punica Granatum): It is madhura, kashaya and amla rasa with ushna veerya and madhur vipaka.  Pomegranates have the potential to thin the blood, increase blood flow to the heart, reduce blood pressure, reduce plaque in the arteries, and reduce bad cholesterol while increasing good cholesterol<ref> Lansky, E.; Shubert, S.; Neeman, I. Pharmacological and therapeutical properties of pomegranate. In Proceedings 1st International Symposium on Pomegranate; Megarejo, P.; Martı´nez, J. J.; </ref>.  Pomegranate seed oil and fermented juice polyphenols tend to inhibit breastcancer cell proliferation, invasion, and promotes apoptosis of breast cancer cells<ref>  N.D., R. Mehta, W. Yu, I. Neeman, T. Livney, A. Amichay, D.Poirier, P. Nicholls, A. Kirby, W. Jiang, R. Mansel, C.Ramachandran, T. Rabi, B. Kaplan, and E. Lansky:Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer.Breast Cancer Research and Treatment 2002; 71(3): 203-17 </ref>.  

   

   

Falasa (Grewia asiatica): has kashaya, amla, madhura rasa and laghu, veerya sheeta guna and madhura vipaka.  It is useful in madatya, pittaprakopa, trishna, daha, hridroga, amavata, vatarakta, shoola, kshaya, rohini, yoniroga, vrana, jwara. It shows a potent antioxidant properties and shows radio protective properties.  

Falasa (Grewia asiatica): has kashaya, amla, madhura rasa and laghu, veerya sheeta guna and madhura vipaka.  It is useful in madatya, pittaprakopa, trishna, daha, hridroga, amavata, vatarakta, shoola, kshaya, rohini, yoniroga, vrana, jwara. It shows a potent antioxidant properties and shows radio protective properties<ref> Sharma KV, Sisodia R. Evaluation of free radical scavenging activity and radioprotective efficacy of Grewia asiatica fruit. J Radio Prot 2009; 29: 429–443. </ref>.  

If we observe the food substances, fruits and other edibles which are advised for the management of apatarpan have high glycemic index. Dates, raisins, and certain fruits mentioned are fast energy giving substances while formulation with sattu are slow energy giving substances.  

If we observe the food substances, fruits and other edibles which are advised for the management of apatarpan have high glycemic index. Dates, raisins, and certain fruits mentioned are fast energy giving substances while formulation with sattu are slow energy giving substances.  

It is very interesting to note that honey and sattu are used both in apatarpan and santarpaniya vyadhis. In santarpanajanya vyadhis, Sattu is used along with certain herbs, which are tikta and katu ras dominant. Apart from herbs oil, ghee and honey in prescribed portion is used. While in apatarpana diseases sattu has been used along with sugar, alcoholic beverages, honey, oil and ghee. This is the importance of samyog (combination) of dravyas mentioned by Charaka elsewhere. Sattu when advised with alcoholic beverages or with certain sour substance exerts different nutritional properties. When sattu is given with acidic and fermented substances like alcohol, an enzymetic degradation of phytic acid of sattu is observed. Such a reduction in phytate may increase the amount of soluble iron, zinc and calcium several folds. This makes the combination of sattu more nutritious as compared to the formulation mentioned in the management of santarpanajanya diseases.       

It is very interesting to note that honey and sattu are used both in apatarpan and santarpaniya vyadhis. In santarpanajanya vyadhis, Sattu is used along with certain herbs, which are tikta and katu ras dominant. Apart from herbs oil, ghee and honey in prescribed portion is used. While in apatarpana diseases sattu has been used along with sugar, alcoholic beverages, honey, oil and ghee. This is the importance of samyog (combination) of dravyas mentioned by Charaka elsewhere. Sattu when advised with alcoholic beverages or with certain sour substance exerts different nutritional properties. When sattu is given with acidic and fermented substances like alcohol, an enzymetic degradation of phytic acid of sattu is observed. Such a reduction in phytate may increase the amount of soluble iron, zinc and calcium several folds. This makes the combination of sattu more nutritious as compared to the formulation mentioned in the management of santarpanajanya diseases.       

Over-nutrition and disorders induced by it leads to immune activation or susceptibility to inflammatory diseases, such as diabetes while under nutrition results in immune suppression or susceptibility to infection. Over-nutrition (prolonged intake of high fat/sugar diets) and infection lead to chronic and acute inflammation through nutrient and pathogen sensing systems, respectively

Over-nutrition and disorders induced by it leads to immune activation or susceptibility to inflammatory diseases, such as diabetes while under nutrition results in immune suppression or susceptibility to infection. Over-nutrition (prolonged intake of high fat/sugar diets) and infection lead to chronic and acute inflammation through nutrient and pathogen sensing systems, respectively<ref> Wellen KE, Hotamisligil GS: Inflammation, stress, and diabetes. J Clin Invest 2005, 115:1111-1119. </ref>

=== List of research works done as post graduate and post doctoral level on hyperlipidemia ===

=== List of research works done as post graduate and post doctoral level on hyperlipidemia ===