Changes

*''Sanchaya'' (accumulation): In this stage ''dosha'' undergo mild increase at their own site. This accumulation produces mild symptoms. If the person recognises these instincts and acts accordingly, the ''doshas'' can be brought to the normal condition without much effort. <ref>Dalhana, Commentator, Sushruta SamhitaSutrasthana Adhyaya 21/18, Seventh Edition, Chaukhambha Orientalia, Varanasi, 2002,103.  </ref>

*''Sanchaya'' (accumulation): In this stage ''dosha'' undergo mild increase at their own site. This accumulation produces mild symptoms. If the person recognises these instincts and acts accordingly, the ''doshas'' can be brought to the normal condition without much effort. <ref>Dalhana, Commentator, Sushruta SamhitaSutrasthana Adhyaya 21/18, Seventh Edition, Chaukhambha Orientalia, Varanasi, 2002,103.  </ref>

*''Prakopa'' (aggravation): In this stage, ''doshas'' gets vitiated further at their own site and exhibit some specific symptoms. By suitable changes in daily routine one can overcome these conditions. </ref>Dalhana, Commentator, Sushruta SamhitaSutrasthana Adhyaya 21/27, Seventh Edition, Chaukhambha Orientalia, Varanasi, 2002,104. </ref>

*''Prakopa'' (aggravation): In this stage, ''doshas'' gets vitiated further at their own site and exhibit some specific symptoms. By suitable changes in daily routine one can overcome these conditions. <ref>Dalhana, Commentator, Sushruta SamhitaSutrasthana Adhyaya 21/27, Seventh Edition, Chaukhambha Orientalia, Varanasi, 2002,104. </ref>

*''Prasara'' (spreading): The status of ''doshas'' again increases further and ''doshas'' spread nearby sites and invade the sites of other ''doshas'' to produce symptoms. If the person continues to indulge in unhealthy food and regimen, then the disease progresses to the next stage. <ref>Dalhana, Commentator, Sushruta SamhitaSutrasthana Adhyaya 21/32, Seventh Edition, Chaukhambha Orientalia, Varanasi, 2002,105. </ref>  

*''Prasara'' (spreading): The status of ''doshas'' again increases further and ''doshas'' spread nearby sites and invade the sites of other ''doshas'' to produce symptoms. If the person continues to indulge in unhealthy food and regimen, then the disease progresses to the next stage. <ref>Dalhana, Commentator, Sushruta SamhitaSutrasthana Adhyaya 21/32, Seventh Edition, Chaukhambha Orientalia, Varanasi, 2002,105. </ref>  

The abnormal changes taking place in the body after exposure to the causative factors up to the manifestation of the disease is called as ''samprapti''. This includes progress of the disease from first to sixth ''kriyakala''.

The abnormal changes taking place in the body after exposure to the causative factors up to the manifestation of the disease is called as ''samprapti''. This includes progress of the disease from first to sixth ''kriyakala''.

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====Interrelation between ''nidanapanchaka'' and ''shatkriyakala'' ====

====Interrelation between ''nidanapanchaka'' and ''shatkriyakala'' ====