Changes

====== ''Veerya'' ======

====== ''Veerya'' ======

An attempt has been made to assess the effects of sheeta and ushna virya drugs (samana pratyayarabdha dravyas) on basal metabolic rate (BMR). Two sheeta virya drugs, namely, yashtimadhu (Glycyrrhiza glabra) and Shatavari (Asparagus racemosus) and two ushna virya drugs, namely, chitraka (Plumbago zeylanica) and jatiphala (Myristica fragrans) were considered for this study. In healthy volunteers, initial BMR was recorded with Mc Kesson metabolizer. Then the drug was administered three times a day (chitraka and jatiphala 2gm each and yashtimadhu and Shatavari 5gm each). A significant increase (p<0.05) was observed with yashti, while the increase in BMR with Shatavari was not very significant. Chitraka and jatiphala brought about a significant decrease in BMR(p<0.05). Therefore, sheetavirya and ushnavirya drugs which represent the saumyatva and agneyatva of a drug or food may be responsible for synthesizing or metabolizing the dhatus due to their santarpaka or apatarpaka actions4.

An attempt has been made to assess the effects of ''sheeta'' and ''ushna veerya'' drugs (''samana pratyayarabdha dravyas'') on basal metabolic rate (BMR). Two ''sheeta veerya'' drugs, namely, ''yashtimadhu'' (Glycyrrhiza glabra) and ''shatavari'' (Asparagus racemosus) and two ''ushna veerya'' drugs, namely, ''chitraka'' (Plumbago zeylanica) and ''jatiphala'' (Myristica fragrans) were considered for this study. In healthy volunteers, initial BMR was recorded with McKesson metabolizer. Then the drug was administered three times a day (''chitraka'' and ''jatiphala'' 2gm each and ''yashtimadhu'' and ''shatavari'' 5gm each). A significant increase (p<0.05) was observed with ''yashti'', while the increase in BMR with ''shatavari'' was not very significant. ''Chitraka'' and ''jatiphala'' brought about a significant decrease in BMR(p<0.05). Therefore, ''sheetaveerya'' and ''ushnaveerya'' drugs which represent the ''saumyatva'' and ''agneyatva'' of a drug or food may be responsible for synthesizing or metabolizing the ''dhatus'' due to their ''santarpaka'' or ''apatarpaka'' actions4.

====== ''Vipaka'' ======

====== ''Vipaka'' ======