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1. Shailaja C. Journal of Health & Population in Developing Countries. Vol. 3. WHO publication; 2000.A few research outcomes relevant for Public Health from Indian System of Medicine; p. 109.
 
1. Shailaja C. Journal of Health & Population in Developing Countries. Vol. 3. WHO publication; 2000.A few research outcomes relevant for Public Health from Indian System of Medicine; p. 109.
 
2. Singh, RH and Rastogi, S. Rasayana Therapy and Rejuvenation. In Evidence based practice of CAM,  PP 177-190. Springer, Germany. 2012
 
2. Singh, RH and Rastogi, S. Rasayana Therapy and Rejuvenation. In Evidence based practice of CAM,  PP 177-190. Springer, Germany. 2012
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=== Vidhi Vimarsha ===
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Pathogenesis of various types of rajayakshma:
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I. Sahasaja rajayakshma: Due to physical exertion like—
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Battle
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Reading
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Weight lifting This increases the inspiration & expiration.
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Travelling on foot
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Leaping Such abnormal breathing injures the
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tissues of lung (Kshat)
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Jumping
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      Injured tissues of lung gets filled with vayu
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This vitiated vayu deranged the kapha & pitta.
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This deranged dosha along with vayu spread in all direction within the body.
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And produce eleven symptoms of rajayakshma due to the over exertion.
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      II. Vegasandharanaja rajayakshma:                   
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                                                            Suppression of natural urges
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Vitiation of vata
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Disruption of agni
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Vitiation of all three doshas
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Obstruction of the channels of circulation.
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These vitiated humours produce the disorder having symptoms of all three doshas.
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III. Kshayaja rajayakshma:
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Excessive sexual indulgence Loss of unctuousness
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Fasting Vitiation of vata
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Excessive bleeding & aggrevated two other doshas
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Envy obstruction of channels circulation
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Eagerness Degradation of dhatus
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Fever & produce 11 symptoms.
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Terror
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Anger
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IV. Vishamashanaja rajayakshma:
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A person who taks food against the ashta-vidhi
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visheshayatan and ten vidhi vidhan.
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This leads to vitiation of vata
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vata aggravates other two doshas
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Obstruction of channels of rasa and other dhatus
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dhatu not nourished properly
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And produce 11 symptoms of rajayakshma due to
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the irregular diet.
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General pathogenesis:
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Nidana
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Sannikrishta Viprikrishta
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Nidana Nidana
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Sahasa Dhatu Samdha-   Visham-
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Kshaya   rana   ashana
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  Shukrakshaya Kapha Pradhan
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Tridosha
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  Vataprakopa Srotovarodha
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Dhatukshaya in Dhatukshaya in
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Pratiloma krama Anuloma krama
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        Sarvadhatu
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            Kshaya
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            Shosha
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                                (Emaciation)
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                          Rajayakshma
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A
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Contemporary Treatments:
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Priniciples of treatments:  Deepana, Srotoshodhana, Balya and Brumhana
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Main drugs: Bala, Abhraka, Suvarna, Kushmanda
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Medicine formulations used:
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I. Sahasaja rajayakshma /urakshata:
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1. Laksha mixture 10 to 20 grams frequently with vasavaleha
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2. Amrutaprasha  10 to 20 grams after meals with milk
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II. Vishamashanaja :
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1. Swarna vasanta 250 to 500 mg between two meals with milk
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2. Drakshasava 10 to 20 ml after meals with water
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III. Vegarodhaja:
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1. Chaturbhuja kalpa 125 to 250 mg before meals with milk and chyavana prasha
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2. Chaturmukha rasa 60 to 120 mg after meals with brahmi prasha
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IV. Kshayaja rajayakshma :
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1. Laksmivilasa rasa 250 to 500 mg between two meals with milk
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2. Vanga mixture 500 to 1000mg between two meals with milk
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==== Cautions for purification treatments ====
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Panchakarma( therapeutic purification) treatments are indicated only in strong patients with excess aggravation of doshas in rajayakshma. In a patient with low strength, purification is not done. If at all, it needs to be done due to excess dosha, then mild purification is prescribed after taking every care of strength of the patient.
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Role of rasayana in enhancing the immunity:
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Rasayana drugs have got an important role in the management of rajayakshma. Mandagni (at the level of jatharagni and dhatwagni both) and srotovarodha play an important role in the pathogenesis of this disease. Rasayana drugs act at various levels to promote nutrition. Some of them work at the level of rasa (enriching nutrient plasma) while others work at the level of agni (improve digestion and metabolism). Some other work at the level of srotas by promoting the competence of microcirculatory channels in the body leading to better bio-availability of nutrients to the tissues and improved tissue perfusion.[2] Hence, rasayana acting at all three levels may prove beneficial in the management of rajayakshma. Rasayana drugs also improve the status of ojas in the body by their immunomodulatory action. Thus these drugs are used as an adjuvant to anti-tubercular drugs and they enhance efficacy of treatment at various levels. Details about rasayana drugs have already been described in first chapter of chikitsa section.  Nidana parivarjan (removal of the causes) is yet another aspect of treatment.
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==== Research on ayurveda treatment in tuberculosis patients ====
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As we look back to the history of tuberculosis treatment, the immune-boost up was the main treatment. Ayurvedic treatment of tuberculosis was initiated in 1933 by the establishment of Patipukur TB Hospital, Kolkata. Later on, a full-fledged research unit was commissioned with exclusive budget. Treatment guidelines were adopted on Ayurvedic principles for therapeutic management which was a unique effort of its kind in pre-independence India. This regimen was discontinued from 1st November 1947 on the introduction of synthetic ATDs. Drugs containing mercury, gold, calcium was prepared at the in-house pharmacy and was administered to the patients with fresh juice of herbs cultivated in the hospital garden. Formulations like vasantamalati, kanchanabhra rasa, rajamriganka rasa were under use including bhallataka (Semicarpus anacardium) rasayan, mallasindura, vasa (Adatoda vasica) etc. The statistics on the treatment of pulmonary tuberculosis using Ayurvedic medicine for over a period of 13 years is of immense value.[1]
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Research outcome relevant for public health from the Indian systems of medicine on tuberculosis at The Patipukur TB Hospital: Modern TB-drugs were administered to about 2766 patients and the cure rate turned out to be 11.42% and the death rate 40.9%. When a group of patients on modern anti-TB drugs received supplementary Ayurvedic drugs, the cure rate was 41.3% and the death rate was 3.8%. Studies have also been conducted to assess the role of Ayurvedic treatment in resistant cases. [1]
      
=== References ===
 
=== References ===

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