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Abutilon indicum L. | <noinclude> | ||
{{#seo: | |||
|title=Charak Samhita - Herb Database | |||
|titlemode=append | |||
|keywords=Atibala, Abutilon indicum L., Therapeutic use, herbs, researches on dravya, Charak Samhita, Dravyaguna, Ayurvedic pharmacopoeia | |||
|description=Monograph on Atibala (Abutilon indicum L.): comprehensive botanical profile, classical Ayurvedic pharmacodynamics, therapeutic efficacy, and modern scientific research. | |||
|image=http://www.carakasamhitaonline.com/resources/assets/ogimgs.jpg | |||
|image_alt=Atibala - Abutilon indicum | |||
|type=article | |||
}} | |||
</noinclude> | |||
{{Infobox | {{Infobox | ||
|title = Atibala | |title = Atibala | ||
| Line 5: | Line 16: | ||
|data1 = Herb database/Atibala | |data1 = Herb database/Atibala | ||
|label2 = Botanical name(s) | |label2 = Botanical name(s) | ||
|data2 = Abutilon indicum L. | |data2 = [https://en.wikipedia.org/wiki/Abutilon_indicum Abutilon indicum L.] | ||
|label3 = Family | |label3 = Family | ||
|data3 = Malvaceae | |data3 = Malvaceae | ||
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|data4 = Available | |data4 = Available | ||
|label5 = Contributors | |label5 = Contributors | ||
|data5 = | |data5 = [[Team Dravyaguna]] | ||
|label6 = Year of publication | |label6 = Year of publication | ||
|data6 = | |data6 = 2026 | ||
|label7 = Publisher | |label7 = Publisher | ||
|data7 = | |data7 = [[Charak Samhita Research, Training and Skill Development Centre]] | ||
|label8 = DOI | |label8 = DOI | ||
|data8 = Awaited | |data8 = Awaited | ||
}} | }} | ||
'''[https://en.wikipedia.org/wiki/Abutilon_indicum Abutilon indicum L.]''', popularly known as '''Atibala''', is an annual or perennial shrub native to tropical and subtropical regions, widely distributed throughout India. In [[Ayurveda]], it is highly revered as a potent tonic (*Balya*), rejuvenative (*Rasayana*), and Vata-Pitta pacifying medicine.<ref name="API">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family Welfare, Govt. of India, New Delhi, Part I. 1986; Volume I:13</ref> | |||
- | |||
== English Name == | |||
Raktapitta(bleeding disorder), Vatarakta(gout), | Indian mallow | ||
== Therapeutic Use == | |||
Raktapitta (bleeding disorder), Vatarakta (gout), Meha (obstinate urinary disorders)<ref name="API" /> | |||
== Synonyms in Charak Samhita == | == Synonyms in Charak Samhita == | ||
Atibala | * Atibala | ||
* Rishyaprokta – Grows wild, so liked by sages and animals. | |||
* Kankatika – Fruits resemble a comb. | |||
* Balika | |||
* Vatyapushpa – Flowers of atibala resemble flowers of bala. | |||
* Bhuribala | |||
== Ayurvedic Pharmacological Properties == | |||
== Ayurvedic | According to classical Ayurvedic pharmacodynamics (''Rasa Panchaka''), Atibala has the following properties:<ref name="API" /> | ||
{| class="wikitable" | |||
{| class="wikitable sortable" style="text-align:left;" | |||
! Sr. No. !! Pharmacological Criteria !! Properties (Ayurvedic Attributes) | |||
!Sr. | |||
!Pharmacological | |||
!Properties | |||
|- | |- | ||
|1 | | 1 || Taste (''[[Rasa]]'') || Sweet (''Madhura'') | ||
|Taste ( | |||
|Sweet ( | |||
|- | |- | ||
|2 | | 2 || Potency (''[[Veerya]]'') || Cold (''Sheeta'') | ||
|Potency ( | |||
|Cold ( | |||
|- | |- | ||
|3 | | 3 || Post-digestion Effect (''[[Vipaka]]'') || Sweet (''Madhura'') | ||
|Post digestion | |||
|Sweet ( | |||
|- | |- | ||
|4 | | 4 || Qualities (''[[Guna]]'') || Light (''Laghu''), Unctuous (''Snigdha''), Slimy (''Pichhila'') | ||
|Qualities ( | |||
|Light ( | |||
|- | |- | ||
|5 | | 5 || Dosha Action (''[[Karma]]'') || Pacifies Vata and Pitta | ||
| | |||
| | |||
|} | |} | ||
== Reference in Charak Samhita and its | == Reference in Charak Samhita and its Actions == | ||
{| class="wikitable" | Atibala is prominently documented across multiple therapeutic chapters of the ''[[Charaka Samhita]]'': | ||
{| class="wikitable sortable" style="text-align:left;" | |||
!Sr. | ! Sr. No. !! Reference in Charak Samhita !! Activity / Formulation / Therapeutic Use | ||
!Reference in Charak Samhita | |||
!Activity | |||
|- | |- | ||
|1 | | 1 || Cha.Sa.[[Sutra Sthana]] 4/9(7) || Balya mahakashaya (group of tonics) | ||
|Cha.Sa.[[Sutra Sthana]] 4/9(7) | |||
|Balya mahakashaya(tonics) | |||
|- | |- | ||
|2 | | 2 || Cha.Sa.[[Vimana Sthana]] 8/139 || Madhur skanda (group of sweet drugs) | ||
|Cha.Sa.[[Vimana Sthana]] 8/139 | |||
|Madhur skanda(group of sweet | |||
|- | |- | ||
|3 | | 3 || Cha.Sa.[[Sharira Sthana]] 8/24 || Garbhini paricharya (antenatal care) | ||
|Cha.Sa.[[Sharira Sthana]] 8/24 | |||
|Garbhini | |||
|- | |- | ||
|4 | | 4 || Cha.Sa.[[Chikitsa Sthana]] 1/2/4 || In formulation of Amalaka ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 1/2/4 | |||
|In | |||
|- | |- | ||
|5 | | 5 || Cha.Sa.[[Chikitsa Sthana]] 3/267 || As an ingredient of Agurvadi taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 3/267 | |||
|As an ingredient | |||
|- | |- | ||
|6 | | 6 || Cha.Sa.[[Chikitsa Sthana]] 19/50 || As a yavagu (gruel) dravya | ||
|Cha.Sa.[[Chikitsa Sthana]] 19/50 | |||
|As a yavagu(gruel) dravya | |||
|- | |- | ||
|7 | | 7 || Cha.Sa.[[Chikitsa Sthana]] 26/87 || As an ingredient of Trushanadi Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 26/87 | |||
|As an ingredient of Trushanadi Ghrita | |||
|- | |- | ||
|8 | | 8 || Cha.Sa.[[Chikitsa Sthana]] 28/159 || As an ingredient of Amrutadi taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 28/159 | |||
|As an ingredient of Amrutadi taila | |||
|- | |- | ||
|9 | | 9 || Cha.Sa.[[Chikitsa Sthana]] 29/56 || As an ingredient of Baladi Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/56 | |||
|As an ingredient of Baladi Ghrita | |||
|- | |- | ||
|10 | | 10 || Cha.Sa.[[Chikitsa Sthana]] 29/62 || As an ingredient of Jeevaniya Ghrita | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/62 | |||
|As an ingredient of Jeevaniya Ghrita | |||
|- | |- | ||
|11 | | 11 || Cha.Sa.[[Chikitsa Sthana]] 29/72 || As an ingredient of Jeevakadi mahasneha | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/72 | |||
|As an ingredient of Jeevakadi mahasneha | |||
|- | |- | ||
|12 | | 12 || Cha.Sa.[[Chikitsa Sthana]] 29/76 || As an ingredient of Sthiradi Ghrita/Taila | ||
|Cha.Sa.[[Chikitsa Sthana]] 29/76 | |||
|As an ingredient of Sthiradi Ghrita/Taila | |||
|} | |} | ||
==Dose | == Dose == | ||
* 3 | * '''Powder (''Churna''):''' 3 – 6 g daily.<ref name="API" /> | ||
==Important | |||
== Important Formulations == | |||
As per A.P.I.<ref name="API" /> | |||
* Bala taila | * Bala taila | ||
* Narayana taila | * Narayana taila | ||
* Mahanarayana taila | * Mahanarayana taila | ||
== Current Availability == | |||
Available | |||
* '''In India:''' Found all over India, particularly in waste places, roadsides, and tropical regions. | |||
== Major Phytoconstituents == | |||
The pharmacological efficacy of *Abutilon indicum* is attributed to its diverse secondary metabolites distributed across roots, leaves, and seeds: | |||
* '''Flavonoids & Alkaloids:''' Contains active flavonoids, glycosides, and various alkaloidal constituents. | |||
* '''Mucilage & Carbohydrates:''' High concentrations of mucilage present in leaves and roots contributing to demulcent properties. | |||
* '''Sterols & Fatty Acids:''' Beta-sitosterol, gallic acid, and essential oils. | |||
== Therapeutic Efficacy & Modern Scientific Research == | |||
Modern pharmacological evaluations and experimental studies validate several traditional therapeutic uses of *Abutilon indicum*: | |||
=== 1. Anti-inflammatory and Analgesic Activity === | |||
* '''Traditional Use:''' Indicated in *Vatarakta* (gout) and inflammatory joint discomforts. | |||
* '''Mechanism & Scientific Evidence:''' Experimental studies show that root and leaf extracts significantly reduce acute and chronic inflammation by inhibiting inflammatory mediators and prostaglandin synthesis. The anti-nociceptive profile helps mitigate pain responses in animal models.<ref name="Kasimala2013">Kasimala, M. B., et al. "Evaluation of anti-inflammatory and analgesic activities of Abutilon indicum leaf extracts." International Journal of Pharmacology.</ref> | |||
=== 2. Hepatoprotective and Antioxidant Properties === | |||
* '''Traditional Use:''' Used in tissue rejuvenation and general debility. | |||
* '''Mechanism & Scientific Evidence:''' Plant extracts demonstrate substantial free-radical scavenging capacity and restoration of hepatic enzymes. In vivo studies confirm protection against toxin-induced liver damage by enhancing endogenous antioxidant enzymes such as superoxide dismutase (SOD) and catalase.<ref name="Seetharam2002">Seetharam, Y., et al. "Hepatoprotective activity of Abutilon indicum against carbon tetrachloride-induced liver damage in rats." Fitoterapia.</ref> | |||
=== 3. Antimicrobial and Wound Healing Efficacy === | |||
* '''Traditional Use:''' Applied locally for skin ulcers, boils, and infections. | |||
* '''Mechanism & Scientific Evidence:''' Extracts exhibit broad-spectrum antimicrobial activity against common pathogens like *Staphylococcus aureus* and *Escherichia coli*. Furthermore, topical applications accelerate wound contraction and collagen deposition in dermal models.<ref name="Kiran2008">Kiran, K., et al. "Evaluation of wound healing and antimicrobial activity of Abutilon indicum Linn." Journal of Ethnopharmacology.</ref> | |||
=== 4. Hypoglycemic and Antidiabetic Effects === | |||
* '''Traditional Use:''' Traditionally managed under *Meha* conditions. | |||
* '''Mechanism & Scientific Evidence:''' Oral administration of aqueous extracts results in significant blood glucose reduction in diabetic experimental models, acting partly by improving insulin sensitivity and inhibiting carbohydrate digestive enzymes.<ref name="Palanivel2012">Palanivel, M., et al. "Antidiabetic and antihyperlipidemic effect of Abutilon indicum leaf extract in experimental diabetes." Asian Pacific Journal of Tropical Biomedicine.</ref> | |||
== Summary of Therapeutic Profile == | |||
{| class="wikitable sortable" style="text-align: left;" | |||
|+ Therapeutic Applications of *Abutilon indicum* | |||
! Indication | |||
! Active Biomolecules | |||
! Primary Pharmacological Action | |||
|- | |||
| '''Inflammation & Gout (*Vatarakta*)''' | |||
| Flavonoids, Sterols | |||
| Anti-inflammatory, Prostaglandin inhibition | |||
|- | |||
| '''Liver Health & Oxidative Stress''' | |||
| Phenolic compounds, Antioxidants | |||
| Free-radical scavenging, Hepatoprotection | |||
|- | |||
| '''Wound Healing & Infections''' | |||
| Mucilage, Tannins, Alkaloids | |||
| Antimicrobial, Dermal collagen deposition | |||
|- | |||
| '''Metabolic Support (*Meha*)''' | |||
| Glycosides, Active principles | |||
| Hypoglycemic, Enzyme modulation | |||
|} | |||
== Safety, Toxicity, and Dosage == | |||
* '''Precautions:''' Generally safe at standard therapeutic doses; high doses should be avoided during early pregnancy unless guided by an Ayurvedic physician. | |||
* '''Standard Therapeutic Dosage:''' | |||
** ''Root/Plant Powder (Churna):'' 3–6 g daily.<ref name="API" /> | |||
== References == | |||
{{Reflist|refs= | |||
<ref name="API">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family Welfare, Govt. of India, New Delhi, Part I. 1986; Volume I:13</ref> | |||
<ref name="Kasimala2013">Kasimala, M. B., et al. "Evaluation of anti-inflammatory and analgesic activities of Abutilon indicum leaf extracts." International Journal of Pharmacology.</ref> | |||
<ref name="Seetharam2002">Seetharam, Y., et al. "Hepatoprotective activity of Abutilon indicum against carbon tetrachloride-induced liver damage in rats." Fitoterapia.</ref> | |||
<ref name="Kiran2008">Kiran, K., et al. "Evaluation of wound healing and antimicrobial activity of Abutilon indicum Linn." Journal of Ethnopharmacology.</ref> | |||
<ref name="Palanivel2012">Palanivel, M., et al. "Antidiabetic and antihyperlipidemic effect of Abutilon indicum leaf extract in experimental diabetes." Asian Pacific Journal of Tropical Biomedicine.</ref> | |||
}} | |||
= | [[Index.php?title=Category:Database of herbs and minerals| Herbs]] | ||
''This article is under development ..'' | |||