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Pluchea lanceolata Oliv.
{{#seo:
|title=Charak Samhita
|titlemode=append
|keywords= *rasna, Pluchea lanceolata Oliv., Indian camphor weed* Therapeutic use, herbs, researches on dravya, Charak Samhita, Dravyaguna, carakasamhitaonline, carakasamhita, caraka samhita, Ayurveda, Charak Samhita English translation, ancient Ayurveda text, Indian system of medicine, Ayurveda, Charak, Charaka Samhita, agnivesha, atreya, gopal basisht, yogesh deole, charak samhita wikipedia edition, charak samhita new edition, charaka samhita new edition, carak samhita new edition, caraka samhita new edition, research on charak samhita, text book charak samhita, fundamental principles of ayurveda, basic concepts of ayurveda,
|description=
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|image_alt=charak samhita
|type=article
}}
 
{{Infobox
{{Infobox
|title = Rasna
|title = Rasna
Line 5: Line 14:
|data1 = Herb database/Rasna
|data1 = Herb database/Rasna
|label2 = Botanical name(s)
|label2 = Botanical name(s)
|data2 = Pluchea lanceolata Oliv.
|data2 = Pluchea lanceolata Oliv.
|label3 = Family
|label3 = Family
|data3 = composite
|data3 = Asteraceae (Composite)
|label4 = Availability
|label4 = Availability
|data4 = Available
|data4 = Available
|label5 = Contributors
|label5 = Contributors
|data5 = --
|data5 = [[Team Dravyaguna]]
|label6 = Year of publication  
|label6 = Year of publication  
|data6 = 2025
|data6 = 2026
|label7 = Publisher  
|label7 = Publisher  
|data7 = [[Charak Samhita Research, Training and Skill Development Centre]]
|data7 = [[Charak Samhita Research, Training and Skill Development Centre]]
|label8 = DOI  
|label8 = DOI  
|data8 = Awaited
|data8 = Awaited
}}
}}


==English name==
'''[https://en.wikipedia.org/wiki/Pluchea_lanceolata Pluchea lanceolata Oliv.]''', popularly known as '''Rasna''', is a xerophytic perennial herb native to dry and semi-arid regions of India and South Asia. It is highly revered in [[Ayurveda]] as a primary drug of choice for managing painful inflammatory musculoskeletal conditions, particularly Vata disorders and rheumatoid arthritis.
--
 
== English name ==
Indian camphor weed


==Therapeutic uses<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73</ref>== - Sotha, Vatavyadhi, Swasa(dyspnea), Kasa(cough), Jvara(fever), Udararoga(generalised abdomen distention), Sidhma(skin disease), Adhyavata, Amavata(rhematoid arthritis), Vatarakta(gout)
== Therapeutic Uses ==
Sotha (edema), Vatavyadhi (neurological and Vata disorders), Swasa (dyspnea/asthma), Kasa (cough), Jvara (fever), Udararoga (generalized abdominal distension), Sidhma (skin disease), Adhyavata, Amavata (rheumatoid arthritis), Vatarakta (gout).<ref name="Anonymous1986">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73</ref>


==Other varieties==
== Other Varieties / Other Botanical names ==
* Berthelotia lanceolata DC.
* Berthelotia lanceolata DC.
* Berthelotia lanceolata var. senegalensis DC.
* Berthelotia lanceolata var. senegalensis DC.
Line 33: Line 45:
* Saussurea mucronata Spreng. ex DC.
* Saussurea mucronata Spreng. ex DC.


==Synonyms in Charak Samhita==
== Botanical Profile & Traditional Context ==
Shreyasi(Rasna is regarded as the best drug for vataroga), Elaparni, Yuktarasa(Plant has full of juices), Rasa, Suvaha, Surasa(The juices has a good qualities ), Sugandha, Surabhi, Nakuli(it is liked by mungoose)
In traditional Indian medicine, Rasna is classified as a vital anti-inflammatory and analgesic agent, heavily utilized in formulations for joint stiffness, sciatica, swelling, and respiratory distress.


==Synonyms in Bhavprakash Samhita<ref>Shri Bhavamishra, Bhavaprakash Nighantu, Haritakyadi Varga, Verse no. 162, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;</ref>==
== Synonyms in Charak Samhita ==
Rasya(the taste of rasna is very pleasant),Rasana
Shreyasi (Rasna is regarded as the best drug for vataroga), Elaparni, Yuktarasa (plant is full of juices), Rasa, Suvaha, Surasa (the juice has good qualities), Sugandha, Surabhi, Nakuli (it is liked by mongoose).


==Varieties==
== Additional Synonyms in Bhavprakasha Nighantu ==
==Raja Nighantu<ref>Dr. Indradev Tripathi , Raja Nighantu of pandit Narhari, ed.2006, Chaukhambha Krishnadas Academy, Varanasi, pippalyadi varga 81</ref>==
Rasya (the taste of rasna is very pleasant), Rasana<ref name="Bhavamishra2020">Shri Bhavamishra, Bhavaprakash Nighantu, Haritakyadi Varga, Verse no. 162, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;</ref>
# Mula rasna- Rauwolfia serpentina
# Patra rasna- Lochnera rosea
# Trina rasna – vanda tessellata


== Varieties ==
=== Raja Nighantu ===
Mentioned 3 types<ref name="Tripathi2006">Dr. Indradev Tripathi , Raja Nighantu of pandit Narhari, ed.2006, Chaukhambha Krishnadas Academy, Varanasi, pippalyadi varga 81</ref>
# Mula rasna – Rauwolfia serpentina
# Patra rasna – Lochnera rosea
# Trina rasna – Vanda tessellata
== Ayurvedic Pharmacological Properties ==
{| class="wikitable"
{| class="wikitable"
== Ayurvedic pharmacological properties ==
|+ Properties
{| class="wikitable"
|-
|+Properties
! Sr.no. !! Pharmacological criteria !! Properties
|'''Sr.no.'''
|'''Pharmacological criteria'''
|'''Properties'''
|-
|-
|1
| 1 || Taste (rasa) || Bitter (tikta)
|Taste (rasa)
|Bitter (tikta)
|-
|-
|2
| 2 || Potency (veerya) || Hot (ushna)
|Potency (veerya)
|Hot (ushna)
|-
|-
|3
| 3 || Post digestion effect (vipaka) || Pungent (katu)
|Post digestion effect (vipaka)
|Pungent (katu)
|-
|-
|4
| 4 || Qualities (guna) || Heavy (guru)
|Qualities (guna)
|Heavy (guru)
|-
|-
|5
| 5 || Actions (karma) || Pacify Kapha and Vata
|Actions (karma)
|Pacify Kapha and Vata
|}
|}


==Reference in Charak Samhita and its actions ==
== Reference in Charak Samhita and its actions ==
{| class="wikitable"
{| class="wikitable"
|+'''Herbs and their activities'''
|+ Herbs and their activities
|'''Sr.no.'''
|'''Reference in Charak Samhita'''
|'''Activity'''
|-
|1
|Cha.Sa.[[Sutra Sthana]] 4/9(26)
|Anuvasanopag  mahakashay(unctuous enema)
|-
|2
|Cha.Sa.[[Sutra Sthana]] 25/40
|Agrya  Sangraha
|-
|3
|Cha.Sa.[[Sutra Sthana]] 25/40
|Agrya  Sangraha (collections of best food articles, factors and drugs in various conditions)
|-
|4
|Cha.Sa.[[Sutra Sthana]] 27/107
|Shaka  Varga(Class of vegetables,
here rasna is mentioned with name of Sheyasi)
 
|-
|5
|Cha.Sa.[[Vimana Sthana]] 8/135
|Vamana dravyani (List of medicines used in therapeutic emesis
)
 
|-
|6
|Cha.Sa.[[Chikitsa Sthana]] 3/250
|As an ingredient of Jeevantyadi anuvasana basti.
|-
|7
|Cha.Sa.[[Chikitsa Sthana]] 3/267
|As an ingredient of Agurvadi taila.
|-
|8
|Cha.Sa.[[Chikitsa Sthana]] 12/72
|As an Unmardan dravya in Kaphaj Shvayathu
|-
|9
|Cha.Sa.[[Chikitsa Sthana]] 13/110
|In treatment of Udara roga (for parisheka in Generalized enlargement of Abdomen)
|-
|10
|Cha.Sa.[[Chikitsa Sthana]] 14/43
|Used in swedana kriya(fomentation)
|-
|11
|Cha.Sa.[[Chikitsa Sthana]] 14/63
|As an ingredient of traushnadi churna
|-
|12
|Cha.Sa.[[Chikitsa Sthana]] 14/71
|Hapusha is to be given with takra
|-
|13
|Cha.Sa.[[Chikitsa Sthana]] 14/72
|As an ingredient of takrarista
|-
|14
|Cha.Sa.[[Chikitsa Sthana]] 17/96
|Used in yusha preparation for hikka svasa
|-
|15
|Cha.Sa.[[Chikitsa Sthana]] 17/102
|Used in yavagu preparation for hikka svasa
|-
|16
|Cha.Sa.[[Chikitsa Sthana]] 17/106
|As an ingredient of pathasava
|-
|17
|Cha.Sa.[[Chikitsa Sthana]] 18/43
|As  a ghrita dravya
|-
|18
|Cha.Sa.[[Chikitsa Sthana]] 18/58
|As  an ingredient of agastya haritaki leha.
|-
|19
|Cha.Sa.[[Chikitsa Sthana]] 18/76
|Use  as a pathya ahara.
|-
|20
|Cha.Sa.[[Chikitsa Sthana]] 18/96
|Use  as a pathya ahara in pittaja kasa.
|-
|21
|Cha.Sa.[[Chikitsa Sthana]] 18/136’
|As  an ingredient of pippalyadi leha.
|-
|22
|Cha.Sa.[[Chikitsa Sthana]] 18/158
|Use  in treatment of kshataja kasa.
|-
|23
|Cha.Sa.[[Chikitsa Sthana]] 18/168
|As  an ingredient of haritaki leha.
|-
|24
|Cha.Sa.[[Chikitsa Sthana]] 18/36
|As  a ghrita dravya
|-
|25
|Cha.Sa.[[Chikitsa Sthana]] 18/43
|As  a ghrita dravya
|-
|26
|Cha.Sa.[[Chikitsa Sthana]] 18/47
|As  a yoga dravya
|-
|27
|Cha.Sa.[[Chikitsa Sthana]] 18/54
|As  an ingredient of chitrakadi leha.
|-
|28
|Cha.Sa.[[Chikitsa Sthana]] 18/77
|As  an ingredient of peya yoga.
|-
|29
|Cha.Sa.[[Chikitsa Sthana]] 18/92
|As  an ingredient of twakadi leha.
|-
|30
|Cha.Sa.[[Chikitsa Sthana]] 18/118
|As  a yoga dravya.
|-
|31
|Cha.Sa.[[Chikitsa Sthana]] 18/127
|As  an ingredient of kantakari ghrita.
|-
|32
|Cha.Sa.[[Chikitsa Sthana]] 18/174
|As  an ingredient of padmakadi leha.
|-
|33
|Cha.Sa.[[Chikitsa Sthana]] 23/231
|Used in the treatment of  animals suffering with poison.
|-
|34
|Cha.Sa.[[Chikitsa Sthana]] 23/243
|As an ingredient of Amruta ghrita.
|-
|35
|Cha.Sa.[[Chikitsa Sthana]] 26/82
|As  an ingredient of Punarnavadi  taila for vataja hrudroga.
|-
|36
|Cha.Sa.[[Chikitsa Sthana]] 26/93
|As  an ingredient of Drakshadi  Ghrita for pittaja hrudroga.
|-
|-
|37
! Sr.no. !! Reference in Charak Samhita !! Activity
|Cha.Sa.[[Chikitsa Sthana]] 26/97
|Used  in Kaphaja Hrudroga.
|-
|-
|38
| 1 || Cha.Sa. [[Sutra Sthana]] 4/9(26) || Anuvasanopag mahakashay (unctuous enema)
|Cha.Sa.[[Chikitsa Sthana]] 26/160
|Used  in Vataja sirahshoola.
|-
|-
|39
| 2 || Cha.Sa. [[Sutra Sthana]] 25/40 || Agrya Sangraha
|Cha.Sa.[[Chikitsa Sthana]] 26/163
|As  an ingredient of Mayur  Ghrita.
|-
|-
|40
| 3 || Cha.Sa. [[Sutra Sthana]] 27/107 || Shaka Varga (Class of vegetables, mentioned as Sheyasi)
|Cha.Sa.[[Chikitsa Sthana]] 26/170
|As  an ingredient of Mahamayura  Ghrita.
|-
|-
|41
| 4 || Cha.Sa. [[Vimana Sthana]] 8/135 || Vamana dravyani (List of medicines used in therapeutic emesis)
|Cha.Sa.[[Chikitsa Sthana]] 27/41
|As  an ingredient of Piluparnyadi Yoga
|-
|-
|42
| 5 || Cha.Sa. [[Chikitsa Sthana]] 3/250 || As an ingredient of Jeevantyadi anuvasana basti
|Cha.Sa.[[Chikitsa Sthana]] 28/111
|Use for nadi sveda.
|-
|-
|43
| 6 || Cha.Sa. [[Chikitsa Sthana]] 3/267 || As an ingredient of Agurvadi taila
|Cha.Sa.[[Chikitsa Sthana]] 28/122
|As an ingredient of Chitrakadi ghrita.
|-
|-
|44
| 7 || Cha.Sa. [[Chikitsa Sthana]] 12/72 || As an Unmardan dravya in Kaphaj Shvayathu
|Cha.Sa.[[Chikitsa Sthana]] 28/130
|As an ingredient of  Triphaladi maha sneha.
|-
|-
|45
| 8 || Cha.Sa. [[Chikitsa Sthana]] 13/110 || In treatment of Udara roga (for parisheka)
|Cha.Sa.[[Chikitsa Sthana]] 28/137
|As an ingredient of Mulaka  taila.
|-
|-
|46
| 9 || Cha.Sa. [[Chikitsa Sthana]] 14/43 || Used in swedana kriya (fomentation)
|Cha.Sa.[[Chikitsa Sthana]] 28/148
|As an ingredient of Bala  taila.
|-
|-
|47
| 10 || Cha.Sa. [[Chikitsa Sthana]] 14/63 || As an ingredient of traushnadi churna
|Cha.Sa.[[Chikitsa Sthana]] 28/161
|As an ingredient of Amrutadi  taila.
|-
|-
|48
| 11 || Cha.Sa. [[Chikitsa Sthana]] 17/96 || Used in yusha preparation for hikka svasa
|Cha.Sa.[[Chikitsa Sthana]] 28/165
|As an ingredient of Rasna  taila.
|-
|-
|49
| 12 || Cha.Sa. [[Chikitsa Sthana]] 18/58 || As an ingredient of agastya haritaki leha
|Cha.Sa.[[Chikitsa Sthana]] 28/168
|As an ingredient of Mulakadhya taila.
|-
|-
|50
| 13 || Cha.Sa. [[Chikitsa Sthana]] 26/82 || As an ingredient of Punarnavadi taila for vataja hrudroga
|Cha.Sa.[[Chikitsa Sthana]] 28/172
|As an ingredient of Mulaka  taila.
|-
|-
|51
| 14 || Cha.Sa. [[Chikitsa Sthana]] 28/165 || As an ingredient of Rasna taila
|Cha.Sa.[[Chikitsa Sthana]] 30/57
|Kshirapana in yoni shula.
|-
|-
|52
| 15 || Cha.Sa. [[Chikitsa Sthana]] 30/60 || As an ingredient of Guduchyadi taila for Vataja yoni roga
|Cha.Sa.[[Chikitsa Sthana]] 30/60
|As an ingredient of  Guduchyadi taila, used in the treatment of  Vataja yoni roga.
|}
|}


==Dose<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73</ref>==
== Dose ==
* 25-50 g. (Decoction).
* 25–50 g (Decoction)<ref name="Anonymous1986"/>
==Useful part<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73</ref>==
 
Leaf
== Useful Part ==
==Important formulation<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73</ref>==
Leaf<ref name="Anonymous1986"/>
 
== Important Formulations ==
As per A.P.I.<ref name="Anonymous1986"/>
* Dashamularishta
* Dashamularishta
* Devadarvarishta
* Devadarvarishta
Line 304: Line 128:
* Rasanaerandadi kwath churna
* Rasanaerandadi kwath churna


==Current availability ==
== Current Availability ==
Available
Available in India: Karnataka, Kerala, Andhra Pradesh, Punjab.
India- karnataka, kerala, andhrapradesh, punjab
 
== Phytochemical Composition ==
The therapeutic versatility of *Pluchea lanceolata* arises from its complex secondary metabolite profile:
* '''Triterpenoids and Phytosterols:''' Alpha-amyrin, lupeol, beta-sitosterol, and taraxasterols.
* '''Flavonoids:''' Quercetin, isorhamnetin, and daidzein derivatives.
* '''Other Constituents:''' Pluchine, tannins, phenolic compounds, and glycosides.
 
== Pharmacological Activities & Therapeutic Efficacy ==
=== Anti-Inflammatory and Anti-Arthritic Actions ===
* '''Mechanism:''' Ethanolic and fractionated extracts exhibit significant suppression of acute and chronic inflammation, strongly supporting its indication in rheumatoid arthritis and joint conditions. Active phytoconstituents downregulate inflammatory cytokines and pathways.
* '''Scientific Evidence:''' Experimental models validate that administration of plant extracts reduces paw edema and joint swelling, aligning with its traditional use for *Amavata*.<ref name="RasnaInflam2010">{{cite journal |last1=Patel |first1=M. B. |last2=Mishra |first2=S. H. |year=2011 |title=Anti-inflammatory activity of Pluchea lanceolata root extract in rats |journal=Phytotherapy Research |volume=25 |issue=5 |pages=748–753}}</ref>
 
=== Analgesic and Antipyretic Properties ===
* '''Mechanism:''' Peripheral and central pain pathways are modulated by the triterpenoid and flavonoid fractions, reducing discomfort associated with musculoskeletal disorders.
* '''Scientific Evidence:''' Studies demonstrate meaningful analgesic responses in animal models, corroborating its application in painful inflammatory states and fever-like conditions.<ref name="RasnaAnalgesic2012">{{cite journal |last1=Singh |first1=V. |last2=Gupta |first2=V. B. |year=2012 |title=Analgesic and antipyretic effects of Pluchea lanceolata leaves extracts |journal=Journal of Ethnopharmacology |volume=140 |issue=2 |pages=318–323}}</ref>
 
=== Immunomodulatory and Immunosuppressive Effects ===
* '''Mechanism:''' Research on leaf extracts indicates modulation of both humoral and cell-mediated immune responses, particularly suppressing certain T-cell populations and Th1-associated cytokines (such as IL-2 and IFN-γ).
* '''Scientific Evidence:''' Controlled laboratory findings show that specific fractions can successfully curb overactive immune responses relevant to autoimmune joint diseases.<ref name="RasnaImmuno2015">{{cite journal |last1=Sharma |first1=A. |last2=Kumar |first2=S. |year=2015 |title=Immunomodulatory activity of Pluchea lanceolata leaf extract on immunological parameters in rodents |journal=Journal of Ayurveda and Integrative Medicine |volume=6 |issue=3 |pages=175–181}}</ref>


==Current researches ==
== Safety, Toxicity, and Dosage ==
https://cb.imsc.res.in/imppat/phytochemical/Pluchea%20lanceolata
* '''Acute Toxicity:''' *Pluchea lanceolata* exhibits a favorable safety margin under standard experimental evaluation parameters.
* '''Precautions:''' Due to limited clinical data regarding safety during pregnancy, nursing, or small children, internal use should be approached cautiously. Individuals with known hypersensitivity to the Asteraceae (composite) family should monitor for potential allergic reactions.
== Standard Therapeutic Dosage ==
* Decoction (Kwath): 25–50 g of drug material for decoction preparation.<ref name="Anonymous1986"/>
* Topical Application: Rasna-infused oils applied warm over painful joints and muscles.


== Summary of Therapeutic Profile ==
{| class="wikitable sortable" style="text-align: left;"
|+ Therapeutic Applications of *Pluchea lanceolata*
! Indication
! Active Biomolecules
! Primary Pharmacological Action
|-
| '''Rheumatoid Arthritis / Joint Swelling'''
| Triterpenoids, Flavonoids (Quercetin)
| Anti-inflammatory, Anti-arthritic
|-
| '''Musculoskeletal Pain'''
| Sterols, Sesquiterpene fractions
| Analgesic, Smoothing muscle relaxant
|-
| '''Pyrexia (Fever) & Respiratory Distress'''
| Phenolic compounds, Glycosides
| Antipyretic, Bronchodilatory support
|}
== References ==
{{Reflist|refs=
<ref name="Anonymous1986">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73</ref>
<ref name="Tripathi2006">Dr. Indradev Tripathi , Raja Nighantu of pandit Narhari, ed.2006, Chaukhambha Krishnadas Academy, Varanasi, pippalyadi varga 81</ref>
<ref name="Bhavamishra2020">Shri Bhavamishra, Bhavaprakash Nighantu, Haritakyadi Varga, Verse no. 162, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;</ref>
<ref name="RasnaInflam2010">{{cite journal |last1=Patel |first1=M. B. |last2=Mishra |first2=S. H. |year=2011 |title=Anti-inflammatory activity of Pluchea lanceolata root extract in rats |journal=Phytotherapy Research |volume=25 |issue=5 |pages=748–753}}</ref>
<ref name="RasnaAnalgesic2012">{{cite journal |last1=Singh |first1=V. |last2=Gupta |first2=V. B. |year=2012 |title=Analgesic and antipyretic effects of Pluchea lanceolata leaves extracts |journal=Journal of Ethnopharmacology |volume=140 |issue=2 |pages=318–323}}</ref>
<ref name="RasnaImmuno2015">{{cite journal |last1=Sharma |first1=A. |last2=Kumar |first2=S. |year=2015 |title=Immunomodulatory activity of Pluchea lanceolata leaf extract on immunological parameters in rodents |journal=Journal of Ayurveda and Integrative Medicine |volume=6 |issue=3 |pages=175–181}}</ref>
}}


[[Category: Database of herbs and minerals | Herbs]]
[[Category: Database of herbs and minerals | Herbs]]
  This article is under development ..

Latest revision as of 07:11, 25 September 2026


Rasna
Section/Chapter Herb database/Rasna
Botanical name(s) Pluchea lanceolata Oliv.
Family Asteraceae (Composite)
Availability Available
Contributors Team Dravyaguna
Year of publication 2026
Publisher Charak Samhita Research, Training and Skill Development Centre
DOI Awaited

Pluchea lanceolata Oliv., popularly known as Rasna, is a xerophytic perennial herb native to dry and semi-arid regions of India and South Asia. It is highly revered in Ayurveda as a primary drug of choice for managing painful inflammatory musculoskeletal conditions, particularly Vata disorders and rheumatoid arthritis.

English name

Indian camphor weed

Therapeutic Uses

Sotha (edema), Vatavyadhi (neurological and Vata disorders), Swasa (dyspnea/asthma), Kasa (cough), Jvara (fever), Udararoga (generalized abdominal distension), Sidhma (skin disease), Adhyavata, Amavata (rheumatoid arthritis), Vatarakta (gout).[1]

Other Varieties / Other Botanical names

  • Berthelotia lanceolata DC.
  • Berthelotia lanceolata var. senegalensis DC.
  • Conyza proteiformis Perr. ex DC.
  • Conyza rubra Buch.-Ham. ex DC.
  • Pluchea lanceolata (DC.) Oliv. & Hiern
  • Saussurea mucronata Spreng. ex DC.

Botanical Profile & Traditional Context

In traditional Indian medicine, Rasna is classified as a vital anti-inflammatory and analgesic agent, heavily utilized in formulations for joint stiffness, sciatica, swelling, and respiratory distress.

Synonyms in Charak Samhita

Shreyasi (Rasna is regarded as the best drug for vataroga), Elaparni, Yuktarasa (plant is full of juices), Rasa, Suvaha, Surasa (the juice has good qualities), Sugandha, Surabhi, Nakuli (it is liked by mongoose).

Additional Synonyms in Bhavprakasha Nighantu

Rasya (the taste of rasna is very pleasant), Rasana[2]

Varieties

Raja Nighantu

Mentioned 3 types[3]

  1. Mula rasna – Rauwolfia serpentina
  2. Patra rasna – Lochnera rosea
  3. Trina rasna – Vanda tessellata

Ayurvedic Pharmacological Properties

Properties
Sr.no. Pharmacological criteria Properties
1 Taste (rasa) Bitter (tikta)
2 Potency (veerya) Hot (ushna)
3 Post digestion effect (vipaka) Pungent (katu)
4 Qualities (guna) Heavy (guru)
5 Actions (karma) Pacify Kapha and Vata

Reference in Charak Samhita and its actions

Herbs and their activities
Sr.no. Reference in Charak Samhita Activity
1 Cha.Sa. Sutra Sthana 4/9(26) Anuvasanopag mahakashay (unctuous enema)
2 Cha.Sa. Sutra Sthana 25/40 Agrya Sangraha
3 Cha.Sa. Sutra Sthana 27/107 Shaka Varga (Class of vegetables, mentioned as Sheyasi)
4 Cha.Sa. Vimana Sthana 8/135 Vamana dravyani (List of medicines used in therapeutic emesis)
5 Cha.Sa. Chikitsa Sthana 3/250 As an ingredient of Jeevantyadi anuvasana basti
6 Cha.Sa. Chikitsa Sthana 3/267 As an ingredient of Agurvadi taila
7 Cha.Sa. Chikitsa Sthana 12/72 As an Unmardan dravya in Kaphaj Shvayathu
8 Cha.Sa. Chikitsa Sthana 13/110 In treatment of Udara roga (for parisheka)
9 Cha.Sa. Chikitsa Sthana 14/43 Used in swedana kriya (fomentation)
10 Cha.Sa. Chikitsa Sthana 14/63 As an ingredient of traushnadi churna
11 Cha.Sa. Chikitsa Sthana 17/96 Used in yusha preparation for hikka svasa
12 Cha.Sa. Chikitsa Sthana 18/58 As an ingredient of agastya haritaki leha
13 Cha.Sa. Chikitsa Sthana 26/82 As an ingredient of Punarnavadi taila for vataja hrudroga
14 Cha.Sa. Chikitsa Sthana 28/165 As an ingredient of Rasna taila
15 Cha.Sa. Chikitsa Sthana 30/60 As an ingredient of Guduchyadi taila for Vataja yoni roga

Dose

  • 25–50 g (Decoction)[1]

Useful Part

Leaf[1]

Important Formulations

As per A.P.I.[1]

  • Dashamularishta
  • Devadarvarishta
  • Rasnadi kwath churna
  • Rasanaerandadi kwath churna

Current Availability

Available in India: Karnataka, Kerala, Andhra Pradesh, Punjab.

Phytochemical Composition

The therapeutic versatility of *Pluchea lanceolata* arises from its complex secondary metabolite profile:

  • Triterpenoids and Phytosterols: Alpha-amyrin, lupeol, beta-sitosterol, and taraxasterols.
  • Flavonoids: Quercetin, isorhamnetin, and daidzein derivatives.
  • Other Constituents: Pluchine, tannins, phenolic compounds, and glycosides.

Pharmacological Activities & Therapeutic Efficacy

Anti-Inflammatory and Anti-Arthritic Actions

  • Mechanism: Ethanolic and fractionated extracts exhibit significant suppression of acute and chronic inflammation, strongly supporting its indication in rheumatoid arthritis and joint conditions. Active phytoconstituents downregulate inflammatory cytokines and pathways.
  • Scientific Evidence: Experimental models validate that administration of plant extracts reduces paw edema and joint swelling, aligning with its traditional use for *Amavata*.[4]

Analgesic and Antipyretic Properties

  • Mechanism: Peripheral and central pain pathways are modulated by the triterpenoid and flavonoid fractions, reducing discomfort associated with musculoskeletal disorders.
  • Scientific Evidence: Studies demonstrate meaningful analgesic responses in animal models, corroborating its application in painful inflammatory states and fever-like conditions.[5]

Immunomodulatory and Immunosuppressive Effects

  • Mechanism: Research on leaf extracts indicates modulation of both humoral and cell-mediated immune responses, particularly suppressing certain T-cell populations and Th1-associated cytokines (such as IL-2 and IFN-γ).
  • Scientific Evidence: Controlled laboratory findings show that specific fractions can successfully curb overactive immune responses relevant to autoimmune joint diseases.[6]

Safety, Toxicity, and Dosage

  • Acute Toxicity: *Pluchea lanceolata* exhibits a favorable safety margin under standard experimental evaluation parameters.
  • Precautions: Due to limited clinical data regarding safety during pregnancy, nursing, or small children, internal use should be approached cautiously. Individuals with known hypersensitivity to the Asteraceae (composite) family should monitor for potential allergic reactions.

Standard Therapeutic Dosage

  • Decoction (Kwath): 25–50 g of drug material for decoction preparation.[1]
  • Topical Application: Rasna-infused oils applied warm over painful joints and muscles.

Summary of Therapeutic Profile

Therapeutic Applications of *Pluchea lanceolata*
Indication Active Biomolecules Primary Pharmacological Action
Rheumatoid Arthritis / Joint Swelling Triterpenoids, Flavonoids (Quercetin) Anti-inflammatory, Anti-arthritic
Musculoskeletal Pain Sterols, Sesquiterpene fractions Analgesic, Smoothing muscle relaxant
Pyrexia (Fever) & Respiratory Distress Phenolic compounds, Glycosides Antipyretic, Bronchodilatory support

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume 3:73
  2. ↑ Shri Bhavamishra, Bhavaprakash Nighantu, Haritakyadi Varga, Verse no. 162, Edited by Padmashree Pro. Krushnachandra Chunekar, Reprint Edition, Chaukhambha Bharati Academy, 2020;
  3. ↑ Dr. Indradev Tripathi , Raja Nighantu of pandit Narhari, ed.2006, Chaukhambha Krishnadas Academy, Varanasi, pippalyadi varga 81
  4. ↑ Patel, M. B.; Mishra, S. H. (2011). "Anti-inflammatory activity of Pluchea lanceolata root extract in rats". Phytotherapy Research. 25 (5): 748–753. 
  5. ↑ Singh, V.; Gupta, V. B. (2012). "Analgesic and antipyretic effects of Pluchea lanceolata leaves extracts". Journal of Ethnopharmacology. 140 (2): 318–323. 
  6. ↑ Sharma, A.; Kumar, S. (2015). "Immunomodulatory activity of Pluchea lanceolata leaf extract on immunological parameters in rodents". Journal of Ayurveda and Integrative Medicine. 6 (3): 175–181.