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It may act through vascular route(myo-enteric venous plexus),nervous route(specifically act on apana&samanavata,hence ENS involved).
 
It may act through vascular route(myo-enteric venous plexus),nervous route(specifically act on apana&samanavata,hence ENS involved).
[[File:Nervous system.jpg|center|frame|]]
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[[File:Nervous system.jpg|center]]
 
There may be possible correlation -
 
There may be possible correlation -
# It modulates endocrine functions  
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# It modulates endocrine functions [[File:Endocrine.jpg]] (myoentericplexus—ANS—Brain—Pituitary—Adrenal ovarian/testicular axis).
[[File:Endocrine.jpg]]
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# It maycauses pressure variation of intestinal mucosa, which may induce difference in intestinal intra- cellular and extra -cellular fluid.
(myoentericplexus—ANS—Brain—Pituitary—Adrenal ovarian/testicular axis).
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# It acts by a curious bio feedback mechanism yet to be identified.
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Basti dravya reaches up to micro & macro levels due to its virya(potency). It helps first to disrupt the pathogenic process &carries  the morbid matter towards the colon (pakwashaya) for elimination. Thus, it acts as a curative as well as purification measure.
 
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