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The jatharagni essentially nourishes the respective [[dhatu]] in the form of dhatvagni residing in each of the [[dhatu]]. [A.H.Sutra Sthana 11/34]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> The dhatvagni is responsible for the increase (vriddhi)/ decrease (kshaya) of the representative [[dhatu]].  The hypo functioning (saada) of the dhatvagni leads to the increase in the respective [[dhatu]]. While hyper functioning (atideepti) leads to diminished production (kshaya) of the [[dhatu]]. Thus, every [[dhatu]]'s metabolism depends on the functions of the dhatvagni, preceding and subsequent [[dhatu]].  

The jatharagni essentially nourishes the respective [[dhatu]] in the form of dhatvagni residing in each of the [[dhatu]]. [A.H.Sutra Sthana 11/34]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> The dhatvagni is responsible for the increase (vriddhi)/ decrease (kshaya) of the representative [[dhatu]].  The hypo functioning (saada) of the dhatvagni leads to the increase in the respective [[dhatu]]. While hyper functioning (atideepti) leads to diminished production (kshaya) of the [[dhatu]]. Thus, every [[dhatu]]'s metabolism depends on the functions of the dhatvagni, preceding and subsequent [[dhatu]].  

Interaction of [[dosha]]-[[dhatu]] (samurchhana) is the basis of pathogenesis. The state of [[agni]] should be considered in the pathogenesis. Any derangement of [[dosha]], if not corrected properly, progresses deeper into the [[dhatu]]s and becomes more challenging to correct. Progressive pathogenesis in any [[dhatu]] should be controlled by specific measures, otherwise it affects other sequential [[dhatu]]s. [Su.Sa.Sutra Sthana 21] So the role of dhatvagni is very important for metabolic disorders like dyslilipdemia (medoroga), obstinate urinary disease including diabetes ([[prameha]]), obesity (sthaulya). [[Agni]] and ultimately the dhatvagni are the basic concepts that are important to rule out the cause and treatment of any disease. The crucial aspects of concept of dhatvagni can be summarized as shown in Figure 1

Interaction of [[dosha]]-[[dhatu]] (samurchhana) is the basis of pathogenesis. The state of [[agni]] should be considered in the pathogenesis. Any derangement of [[dosha]], if not corrected properly, progresses deeper into the [[dhatu]]s and becomes more challenging to correct. Progressive pathogenesis in any [[dhatu]] should be controlled by specific measures, otherwise it affects other sequential [[dhatu]]s. [Su.Sa.Sutra Sthana 21]<ref name= Susruta> Sushruta. Sushruta Samhita. Edited by Jadavaji Trikamji Aacharya. 8th ed. Varanasi: Chaukhambha Orientalia;2005.</ref> So the role of dhatvagni is very important for metabolic disorders like dyslilipdemia (medoroga), obstinate urinary disease including diabetes ([[prameha]]), obesity (sthaulya). [[Agni]] and ultimately the dhatvagni are the basic concepts that are important to rule out the cause and treatment of any disease. The crucial aspects of concept of dhatvagni can be summarized as shown in Figure 1

This concept can also be depicted through the flowchart as given in Figure 2 [Dalhana on Su.Sa.Sutra Sthana 14/10]<ref name=Susruta/>

This concept can also be depicted through the flowchart as given in Figure 2 [Dalhana on Su.Sa.Sutra Sthana 14/10]<ref name=Susruta/>