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[[Agni]] is the physiological entity responsible for the status of [[dosha]]. [Cha.Sa.[[Chikitsa Sthana]]5/136] The dhatvagni being a part of this [[agni]] component, is thus equally responsible in the maintenance of health and even in the affliction of diseases. The dhatvagni is a determinant of the production and functions of [[dhatu]]. Hence its proper functioning is of utmost importance in health. Imbalance can lead to disease manifestation. For instance, in condition like [[raktapitta]], the excessive [[pitta]] is responsible for the overstimulation of [[agni]] and dhatvagni, leading to the depletion of quality of [[rakta dhatu]] and liquidity (dravana).[Cha.Sa.[[Chikitsa Sthana]] 4/8] Here the dhatvagni is overstimulated, leading to an imbalance in the tissue metabolism. Also, in conditions like obesity (sthoulya), the [[meda dhatu]] metabolism weakens, leading to excessive [[meda]] (fat deposition). Undernourishment of the remaining [[dhatu]] depicts the slow metabolism of meda (meda-dhatvagnimandya) in the body. [Cha.Sa.[[Sutra Sthana]] 21/5-8]
 
[[Agni]] is the physiological entity responsible for the status of [[dosha]]. [Cha.Sa.[[Chikitsa Sthana]]5/136] The dhatvagni being a part of this [[agni]] component, is thus equally responsible in the maintenance of health and even in the affliction of diseases. The dhatvagni is a determinant of the production and functions of [[dhatu]]. Hence its proper functioning is of utmost importance in health. Imbalance can lead to disease manifestation. For instance, in condition like [[raktapitta]], the excessive [[pitta]] is responsible for the overstimulation of [[agni]] and dhatvagni, leading to the depletion of quality of [[rakta dhatu]] and liquidity (dravana).[Cha.Sa.[[Chikitsa Sthana]] 4/8] Here the dhatvagni is overstimulated, leading to an imbalance in the tissue metabolism. Also, in conditions like obesity (sthoulya), the [[meda dhatu]] metabolism weakens, leading to excessive [[meda]] (fat deposition). Undernourishment of the remaining [[dhatu]] depicts the slow metabolism of meda (meda-dhatvagnimandya) in the body. [Cha.Sa.[[Sutra Sthana]] 21/5-8]
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In the disease [[rajayakshma]], depletion of [[dhatu]] is observed. Dhatvagni plays a pivotal role in the pathological process.[Cha.Sa.[[Chikitsa Sthana]] 8/39-40] The text mentions the term' ushma' in various instances while explaining the metabolism and formation of different [[dhatu]] ([[rakta dhatu]], [[mamsa dhatu]], [[asthi dhatu]]). [Cha.Sa.[[Chikitsa Sthana]] 15/28-31] This concept is also applicable in the pathogenesis of [[pandu]] roga, where the nourishment of [[dhatu]] is hampered leading to laxity and heaviness of [[dhatu]] (dhatushaithilya and dhatugaurava). The quality of the rasa-raktadi dhatu is hampered to a great extent in this condition.[Cha.Sa.[[Chikitsa Sthana]] 16/4-6] The dhatugata disorders are result of dysfunctions of dhatvagni. Dhatvagni is responsible for breakdown (bhinnasanghata), oxidation (dahana) leading to heat or energy generation (tapana).
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In the disease [[rajayakshma]], depletion of [[dhatu]] is observed. Dhatvagni plays a pivotal role in the pathological process.[Cha.Sa.[[Chikitsa Sthana]] 8/39-40] The text mentions the term 'ushma' in various instances while explaining the metabolism and formation of different [[dhatu]] ([[rakta dhatu]], [[mamsa dhatu]], [[asthi dhatu]]). [Cha.Sa.[[Chikitsa Sthana]] 15/28-31] This concept is also applicable in the pathogenesis of [[pandu]] roga, where the nourishment of [[dhatu]] is hampered leading to laxity and heaviness of [[dhatu]] (dhatushaithilya and dhatugaurava). The quality of the rasa-raktadi dhatu is hampered to a great extent in this condition.[Cha.Sa.[[Chikitsa Sthana]] 16/4-6] The dhatugata disorders are result of dysfunctions of dhatvagni. Dhatvagni is responsible for breakdown (bhinnasanghata), oxidation (dahana) leading to heat or energy generation (tapana).
    
==Recent researches on dhatvagni==
 
==Recent researches on dhatvagni==
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