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==== Factors responsible for increase and decrease of body elements ====
 
==== Factors responsible for increase and decrease of body elements ====
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A factor which is responsible for the increase of one dhatu will at the same time reduce the dhatu of opposing properties. For example, milk increases kapha and shukra and at the same time, reduces vata etc. which are of opposing properties. With this view, the authors have used a verb bhavatah, which is dvivachana (changes are happening in two dhatus).  
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A factor which is responsible for the increase of one ''dhatu'' will at the same time reduce the dhatu of opposing properties. For example, milk increases ''kapha'' and ''shukra'' and at the same time, reduces ''vata'' etc. which are of opposing properties. With this view, the authors have used a verb ''bhavatah'', which is ''dvivachana'' (changes are happening in two ''dhatus'').  
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Cow’s urine and kapha dosha share similar physical properties i.e. both are liquid. Still cow’s urine reduces kapha because of differences in other attributes, viz. katu (pungent), ushna (producing heat in the body), ruksha(dry, desiccating) etc. Thus, it can be inferred that more than the physical nature (jati),the attributes (guna) are responsible for the increase or decrease of dhatu, and to reiterate this, the term guna has been added as a suffix to viparita (opposite) in the text.
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Cow’s urine and ''kapha dosha'' share similar physical properties i.e. both are liquid. Still cow’s urine reduces ''kapha'' because of differences in other attributes, viz. ''katu'' (pungent), ''ushna'' (producing heat in the body), ''ruksha''(dry, desiccating) etc. Thus, it can be inferred that more than the physical nature (''jati''),the attributes (''guna'') are responsible for the increase or decrease of ''dhatu'', and to reiterate this, the term ''guna'' has been added as a suffix to ''viparita'' (opposite) in the text.
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The concept explained here is simultaneous changes happening in two or more dhatus having mutually opposite attributes. An etiological or causative factor can cause an increase or decrease in different body elements disturbing the equilibrium. It is possible that the introduction of the etiological or causative factor may be catalyzing a cascade of events either independent or related to the dhatu bringing changes in them. This concept can be further understood by the concept of “cross-organ talks” explained in modern medicine. When there is change in status of any organ, there can be changes seen even in the distant organs through cellular networks.  For example, adipose tissue is an endocrine organ. The tissue produces and secretes a wide range of mediators regulating adipose tissue function in an auto-/paracrine manner and important distant targets, such as the liver, skeletal muscle, the pancreas and the cardiovascular system. The enlargement of adipocytes leads to adipose tissue dysfunction and a shift in the secretory profile with an increased release of pro-inflammatory adipokines in metabolic disorders such as obesity. Adipose tissue dysfunction has a central role in the development of insulin resistance, type 2 diabetes, and cardiovascular diseases. (Romacho T). [3]
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The concept explained here is simultaneous changes happening in two or more ''dhatus'' having mutually opposite attributes. An etiological or causative factor can cause an increase or decrease in different body elements disturbing the equilibrium. It is possible that the introduction of the etiological or causative factor may be catalyzing a cascade of events either independent or related to the ''dhatu'' bringing changes in them. This concept can be further understood by the concept of “cross-organ talks” explained in modern medicine. When there is change in status of any organ, there can be changes seen even in the distant organs through cellular networks.  For example, adipose tissue is an endocrine organ. The tissue produces and secretes a wide range of mediators regulating adipose tissue function in an auto-/paracrine manner and important distant targets, such as the liver, skeletal muscle, the pancreas and the cardiovascular system. The enlargement of adipocytes leads to adipose tissue dysfunction and a shift in the secretory profile with an increased release of pro-inflammatory adipokines in metabolic disorders such as obesity. Adipose tissue dysfunction has a central role in the development of insulin resistance, type 2 diabetes, and cardiovascular diseases. (Romacho T). [3]
    
==== Objective of therapy ====
 
==== Objective of therapy ====