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|description=Deepana is a therapy which includes medicines that kindle/stimulate the digestion process
 
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The word ‘deepana’ literally means kindling, inflaming, setting on fire. In human biology, it means stimulating digestion.<ref>Monier-Williams, Monier-Williams Sanskrit- English Dictionary, 1st edition; Oxford University Press, dipana, Page 481.</ref> Deepana is a pacification treatment [A.Hr.Sutra Sthana 14/6]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> especially for [[kapha]][[dosha]]. It is an essential prerequisite before therapeutic emesis ([[vamana]]) and therapeutic purgation ([[virechana]]). [A.Hr.Sutra Sthana 13/29]<ref name=Hridaya/>
 
{{Infobox
 
 
 
|title =  Contributors
 
 
 
|label1 = Section/Chapter/topic
 
|data1 = [[Chikitsa]] / [[Deepana]]
 
 
 
|label2 = Authors
 
|data2 =Aneesh E.G., Deole Yogesh S.
 
 
 
|label3 = Reviewed and Edited by
 
|data3 = Basisht G.
 
 
 
|label4 = Affiliations
 
|data4 = [[Charak Samhita Research, Training and Development Centre]], I.T.R.A., Jamnagar, India,
 
 
 
 
|label5 = Correspondence email:
 
|data5 = carakasamhita@gmail.com
 
 
 
|label6 = Date of first publication:
 
|data6 = April 26, 2021
 
 
 
|label7 = DOI
 
|data7 = Awaited
 
}}
 
 
 
<div style='text-align:justify;'>
 
==Etymology, derivation, definition and synonyms==
 
 
The word deepana is derived from the word ‘deepa’, which means ‘kindling the fire’ with ‘nich’ and ‘lyu’ suffix. [Vachaspatyam]
 
 
 
=== Definition and synonyms ===
 
 
The diet or medicine or process which stimulates digestion is called ‘deepana’.[Sha.Sa. Purvakhanda 04/01]<ref name= Shargadara> Sharangadhara. Sharangadhara Samhita. Translated from Sanskrit by K.R. Srikantha Murthy. Reprint ed. Varanasi: Chaukhambha orientalia;2016.</ref> It is worthy to note the difference between deepana and [[pachana]]. Deepana process stimulates digestion at a primary level. Whereas [[pachana]] process additionally stimulates metabolism too.
 
 
 
'''Synonyms:''' Sandeepana, agni deepana
 
 
 
== Deepana therapy ==
 
 
 
=== Effect on [[agni]] ===
 
 
 
[[Agni]] (processes of digestion and metabolism) is an important component of health. Qualitative or quantitative impairment of [[agni]] is the fundamental cause of all diseases. [A.Hr.Nidana Sthana 12/1]<ref name=Hridaya/> Deepana treatment intends to maintain equilibrium of [[agni]].
 
 
 
A wide range of food items, medicines have deepana effect. The best form of food to kindle digestion is unctuous food like fats/oils (sneha).[Cha.Sa.[[Chikitsa Sthana]] 15/201] The medicines with deepana action have predominance of [[agni mahabhuta]].[Su.Sa.Sutra Sthana 41/6]<ref name= Susruta> Sushruta. Sushruta Samhita. Edited by Jadavaji Trikamji Aacharya. 8th ed. Varanasi: Chaukhambha Orientalia;2005.</ref>
 
 
 
*'''Tastes (rasa):''' Salt (lavana), bitter (tikta) [Cha.Sa.[[Sutra Sthana]] 26/43], spicy (katu) [Su.Sa.Sutra Sthana 42/10]<ref name=Susruta/> taste have deepana effect.
 
 
 
*'''Properties:''' Hot (ushna) property shows deepana effect.
 
 
 
*'''Herbs with deepana effect:''' Anethum sowa(shatapushpa), Tinospora cordifolia (guduchi), Azadirachta indica(nimba), Santalum album(chandana), Prunus cerasoides(padmaka), Piper longum(pippali), Piper nigrum(maricha), Zingiber officinale(sunti), Aegle marmelos(bilwa), Clerodendrum phlomidis(agnimanda), Cyperus rotundus(musta), Terminalia chebula(haritaki) etc.
 
 
 
*'''Food and beverages:''' Hot water[Su.Sa.Sutra Sthana 45/39]<ref name=Susruta/>, coconut water [Su.Sa.Sutra Sthana 45/43]<ref name=Susruta/>, cow’s milk [Su.Sa.Sutra Sthana 45/51]<ref name=Susruta/>, breast milk[Su.Sa.Sutra Sthana 45/57]<ref name=Susruta/>, buttermilk, alcohol, honey, salt, asafoetida.
 
 
 
*'''Daily regimen:''' Bath [A.Hr.Sutra Sthana 2/16]<ref name=Hridaya/>
 
 
 
== Importance in the preservation of health and prevention ==
 
 
 
Deepana is highly important to maintain the equilibrium of [[agni]] (digestion and metabolism) to preserve health. In the rainy season, the digestive capacity is naturally weak due to seasonal effects. Therefore, the diet and medicines with deepana effect are advised in this season to maintain [[agni]] and prevent the diseases. [Su.Sa.Uttara Sthana 64/7]<ref name=Susruta/> 
 
 
== Importance in management of disease ==
 
 
 
Deepana treatment is indicated in many diseases. Few examples are given below:
 
 
*Hot water is given in the treatment of [[jwara]].[Cha.Sa.[[Chikitsa Sthana]] 3/144]
 
*Butter milk in [[kapha]] dominant gulma [Cha.Sa.[[Chikitsa Sthana]] 8/119] and all digestive disorders [Cha.Sa.[[Chikitsa Sthana]] 15/117], [Su.Sa.Uttara Sthana 40/182]<ref name=Susruta/>
 
*For patients of tuberculosis (rajayakshma) suffering from bouts of diarrhea (atisara) [Cha.Sa.[[Chikitsa Sthana]] 8/134]
 
*For improving taste in mouth[Cha.Sa.[[Chikitsa Sthana]] 8/136]
 
*For the treatment of debility due to injury(kshatakheena)[Cha.Sa.[[Chikitsa Sthana]] 11/84]
 
*For the treatment of piles/hemorrhoids (arsha) [Cha.Sa.[[Chikitsa Sthana]] 14/250]
 
*For the treatment of [[ama]] stuck inside the intestine (pakvashaya) [Cha.Sa.[[Chikitsa Sthana]] 15/75]
 
*In the initial stages of kshayaja kasa.[Cha.Sa.[[Chikitsa Sthana]] 18/150]
 
*[[Vata]] [[dosha]] aggravation in the alimentary tract[Cha.Sa.[[Chikitsa Sthana]] 28/89]
 
*[[Vata]] [[dosha]] functions, obstructed by excess food (annavrutavata) [Cha.Sa.[[Chikitsa Sthana]] 28/196]
 
*Occlusion of apanavata by samanavata[Cha.Sa.[[Chikitsa Sthana]] 28/206]
 
*Occlusion of udanavata by apanavata[Cha.Sa.[[Chikitsa Sthana]] 28/211]
 
*For the treatment of distension of abdomen(adhmana) [Su.Sa.Chikitsa Sthana 5/26]<ref name=Susruta/>
 
 
 
==== Time of administration ====
 
 
 
The deepana medicines should be administered with food. [Su.Sa.Uttara Sthana 64/75]<ref name=Susruta/>
 
 
 
=== Prerequisite before purification therapy ===
 
 
 
Deepana treatment is given before purification therapies to improve digestion and detach [[dosha]] stuck in body channels or to body tissues. [Hemadri on A.Hr Sutra Sthana 13/29]<ref name=Hridaya/> Thus, it facilitates free movement of [[dosha]] and metabolic toxins for removal during purification therapy. If purification therapies are given without proper assessment of states of [[dosha]], it may cause untoward effects.
 
 
=== After purification therapy ===
 
 
 
The digestive capacity is weak after the purification therapies. The light-to-digest diet with deepana effect is advised to normalize digestion. [A.Hr.Sutra Sthana 27/52]<ref name=Hridaya/>
 
 
 
=== Medicinal formulations with deepana effect ===
 
 
*Talisadi churna[Cha.Sa.[[Chikitsa Sthana]] 8/146]
 
*Takrarishta[Cha.Sa.[[Chikitsa Sthana]] 14/75]
 
*Pippalyadi ghrita [Cha.Sa.[[Chikitsa Sthana]] 14/118]
 
*Dantyarishta [Cha.Sa.[[Chikitsa Sthana]] 14/147]
 
*Dadimadi ghrita [Cha.Sa.[[Chikitsa Sthana]] 16/46]
 
*Kantakari ghrita [Cha.Sa.[[Chikitsa Sthana]] 18/35]
 
*Ashtangalavana [Cha.Sa.[[Chikitsa Sthana]] 24/178] etc.
 
 
 
== Contemporary views and current researches ==
 
 
 
Deepana effect can be studied in terms of factors stimulating digestion. The digestive hormones like gastrin, secretin, cholecystokinin may increase after deepana treatment. More specifically, the hormones ghrelin and leptin seem to play an important role in producing deepana effect.
 
 
 
Ghrelin is an orexigenic hormone secreted from the stomach. The concentration of ghrelin in plasma rises before food intake. It falls after the ingestion of food. While administered peripherally, there was an increase in food intake. It also activates a group of neurons in hypothalamus called as AgRP(agoutirelated peptide)neurons. Asprosin is another orexigenic hormone that activates AgRP directly. In animal studies, it is observed that AgRP neurons are activated when there is a deficiency in calories and becomes less active when fed. When the AgRP neurons were activated through chemical or light stimulus, they start to eat intensely in already fed animals. So these neurons are considered hunger-promoting neurons.<ref>L R Beutler, Z A Knight. A spotlight on appetite. Neuron. 2018 February 21; 97(4): 739–741. doi:10.1016/j.neuron.2018.01.050</ref>
 
 
 
Leptin is an anorexigenic hormone secreted by adipose tissue. Its main function is to maintain adequate fat storage in body. A fall in leptin level stimulates hunger.<ref>M L Andermann, B B Lowell. Towards a wiring-diagram understanding of appetite control. Neuron. 2017 August 16; 95(4): 757–778. doi:10.1016/j.neuron.2017.06.014.</ref>  Thus, these two hunger-promoting hormones can have a role in deepana action.
 
 
 
More research on deepana therapy is needed to study the exact mechanism of action.
 
 
 
=== List of thesis done ===
 
 
 
#Jaidev Gehija (2018): Efficacy of Paushtika biscuit with and without deepana pacahana in the management of karshya (Malnutrition) – An open labeled, randomized, comparative clinical trial. Department of KaumaraBhritya, IPGT&RA  Jamnagar
 
 
 
=== Abbreviations ===
 
 
 
Cha. = Charak, Su. = Sushruta, A. = Ashtanga, S. = Sangraha, Hr. = Hridayam, Sha. = Shargadara, Sa. = Samhita.
 
 
 
=== List of references ===
 
 
 
The list of references for deepana in Charak Samhita can be seen [[Media:List_of_references_for_word_Dipana_in_Charaka-converted.pdf|here]]
 
 
 
==References==
 
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