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<p style='text-align:justify;'>Ama means the undigested and unmetabolized components present in the body. More information on concept of ama can be read [[Trividhakukshiya_Vimana#Concept_of_ama|here]]. </p>
 
<p style='text-align:justify;'>Ama means the undigested and unmetabolized components present in the body. More information on concept of ama can be read [[Trividhakukshiya_Vimana#Concept_of_ama|here]]. </p>
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== Contemporary views and research updates on ama ==  
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== Current research updates ==  
    
Ama is an important principle to understand the etiopathogenetic of all disorders and to decide the treatment modalities. [[Agni]] is the digestive and metabolic factor responsible for any transformation in body. Transformation of food material predominantly takes place at the level of gastrointestinal tract ([[grahani]]-seat of jatharagni) and at the level of tissues (dhatvagni-abodes of [[dhatu]]). Dysfunction of [[agni]] results into undigested or partly digested intermediator product called as ama. Ama act as toxic element and form the basis for many pathological conditions. It can be considered raw, uncooked, unripe, immature, undigested or incompletely oxidized / metabolized or similar to a poisonous substance that disrupts body physiology. Accumulation of metabolic waste ([[mala]]) may takes place at various levels in body physiology. The amalgamation of aggravated [[dosha]] with metabolic waste results in ama formation, which is considered the initial stage of disease formation. Origin of ama is mainly considered from gastrointestinal tract ([[amashaya]]). [[Agni]] functions at different levels; hence, ama can be formed at different levels at different body sites. Forms of [[agni]] - jatharagni, bhutagni and dhatvagni functions at different level hence any impairment at the corresponding level leads to ama formation.
 
Ama is an important principle to understand the etiopathogenetic of all disorders and to decide the treatment modalities. [[Agni]] is the digestive and metabolic factor responsible for any transformation in body. Transformation of food material predominantly takes place at the level of gastrointestinal tract ([[grahani]]-seat of jatharagni) and at the level of tissues (dhatvagni-abodes of [[dhatu]]). Dysfunction of [[agni]] results into undigested or partly digested intermediator product called as ama. Ama act as toxic element and form the basis for many pathological conditions. It can be considered raw, uncooked, unripe, immature, undigested or incompletely oxidized / metabolized or similar to a poisonous substance that disrupts body physiology. Accumulation of metabolic waste ([[mala]]) may takes place at various levels in body physiology. The amalgamation of aggravated [[dosha]] with metabolic waste results in ama formation, which is considered the initial stage of disease formation. Origin of ama is mainly considered from gastrointestinal tract ([[amashaya]]). [[Agni]] functions at different levels; hence, ama can be formed at different levels at different body sites. Forms of [[agni]] - jatharagni, bhutagni and dhatvagni functions at different level hence any impairment at the corresponding level leads to ama formation.