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<p style="text-align:justify;">Charak Samhita mentions that the calamities never resulted from any factor other than adharma (unrighteousness). In the first era (kritayuga or satyayuga), people were gifted with liveliness. Their bodies were firm, compact and stable like that of the mountains, they had clear senses and complexions. They had movement, strength and valour. They were truthful, honest, compassionate, chivalrous, self-restraint, disciplined, spiritual, had tendency to fast, and religious deeds. They were devoid of negative emotions like fear, desire, aversion, infatuation, greed, anger, etc. The flora and fauna was well flourished and of high quality , promoting the health of the individuals.  
 
<p style="text-align:justify;">Charak Samhita mentions that the calamities never resulted from any factor other than adharma (unrighteousness). In the first era (kritayuga or satyayuga), people were gifted with liveliness. Their bodies were firm, compact and stable like that of the mountains, they had clear senses and complexions. They had movement, strength and valour. They were truthful, honest, compassionate, chivalrous, self-restraint, disciplined, spiritual, had tendency to fast, and religious deeds. They were devoid of negative emotions like fear, desire, aversion, infatuation, greed, anger, etc. The flora and fauna was well flourished and of high quality , promoting the health of the individuals.  
 
[[File:Adharma1.jpg|center]]
 
[[File:Adharma1.jpg|center]]
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Towards the end of the satyayuga, due to the rise in adharma people started to get heavy (shareera gaurava) due to over-indulgence in food. They started suffering from fatigue (shrama) as a result of this. Fatigue gave rise to laziness (alasya), and laziness made them to accumulate things (sanchaya) which led to the attachment (parigraha) for these things and attachment resulted in greed (lobha). (Figure 1: resultant of adharma in satyayuga)
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[[File:Adharma2.jpg|center]]
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After the onset of the Tretayuga, greed gave rise to malice (abhidroha), malice led to many unfavourable psychological attributes like falsehood (anritavachana), and falsehood led to passion (kaama), anger (krodha), vanity (maana), hatred (dwesha), cruelty (parushya), aggression (abhighata), fear (bhaya), grief (shoka), anxiety (taapa), distress (chinta) etc. Thus during the Tretayuga, one-fourth (1 paada) of dharma (religious duties) depleted resulting in reduction of the life-span of human beings by a quarter. (Figure 2: Resultant of adharma during tretayuga)
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<br/>Similarly, there was reduction in the attributes of environment as well. Due to above phenomena there was diminution by one quarter of the unctuousness, purity, taste (rasa), potency (veerya),  post digestive effect (vipaka), specific effect (prabhava) and qualities of grains. There was an unusual change in the maintenance of equilibrium of tissue elements and there was vitiation of agni (pitta) and maruta (vata) by which bodies of living beings got afflicted with diseases viz. jwara (fever) etc. Therefore, the life-span of living beings gradually diminished.
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<br/>Those who follow the path of adharma are also considered to be unsuitable for the treatment of janapadodhwansa vyadhi including the purification therapies (doshavasechana or shodhana). (Cha. Sa. Vimana Sthana 3/45, Chakrapani on Cha. Sa. Vimana Sthana 3/45), (Cha. Sa. Siddhi Sthana 2/4-5)
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