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|title=Majja dhatu
|title=Majja dhatu
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|type=article
|type=article
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<p style="text-align:justify;">Majja literally means the marrow. Majja dhatu is the body component similar to bone marrow, the soft organic material that fills the cavities of the bones.(SAT-B.443)<ref>Available from http//namstp.ayush.gov.in/#/sat accessed on 05/06/2020</ref> </p>
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Majja literally means the marrow. Majja dhatu is the body component similar to bone marrow, the soft organic material that fills the cavities of the bones.(SAT-B.443)<ref>Available from http//namstp.ayush.gov.in/#/sat accessed on 05/06/2020</ref>
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|data5 = carakasamhita@gmail.com
|data5 = carakasamhita@gmail.com
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|label6 = Date of first publication:
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|label6 = Publisher
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|data6 =June 16, 2020
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|data6 = [[Charak Samhita Research, Training and Development Centre]], I.T.R.A., Jamnagar, India
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|label7 = DOI
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|data7 = [https://doi.org/10.47468/CSNE.2020.e01.s09.018 10.47468/CSNE.2020.e01.s09.018]
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|label7 = Date of first publication:
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|data7 =June 16, 2020
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|label8 = DOI
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|data8 = [https://doi.org/10.47468/CSNE.2020.e01.s09.018 10.47468/CSNE.2020.e01.s09.018]
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*Bone marrow-derived mesenchymal stem cells (BM-MSCs) have the potential of differentiation and they secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. A study conducted to evaluate the healing effect of BM-MSCs transplantation on germinal cells showed that the transplanted BM-MSCs could successfully induce spermatogenesis in seminiferous tubules of azoospermic hamster. Therefore, BM-MSCs can be an attractive candidate in cell transplantation of azoospermia.<ref>Tamadon A et al, Induction of Spermatogenesis by Bone Marrow-derived Mesenchymal Stem Cells in Busulfan-induced Azoospermia in Hamster,Int J Stem Cells. 2015 Nov;8(2)134-45. doi 10.15283/ijsc.2015.8.2.134</ref>
*Bone marrow-derived mesenchymal stem cells (BM-MSCs) have the potential of differentiation and they secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. A study conducted to evaluate the healing effect of BM-MSCs transplantation on germinal cells showed that the transplanted BM-MSCs could successfully induce spermatogenesis in seminiferous tubules of azoospermic hamster. Therefore, BM-MSCs can be an attractive candidate in cell transplantation of azoospermia.<ref>Tamadon A et al, Induction of Spermatogenesis by Bone Marrow-derived Mesenchymal Stem Cells in Busulfan-induced Azoospermia in Hamster,Int J Stem Cells. 2015 Nov;8(2)134-45. doi 10.15283/ijsc.2015.8.2.134</ref>
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*In a clinical study, it is observed that majja basti (therapeutic enema with bone marrow) along with oral intake of asthi shrinkhala(Cissus quadrangularis) shows encouraging results in the management of osteoporosis (asthi-majjakshaya) and it also improves the general health of the patients.<ref>Ajay K. Gupta et al, Effect of Majja Basti (therapeutic enema) and Asthi Shrinkhala (Cissus quadrangularis) in the management ofOsteoporosis (Asthi-Majjakshaya),AYU , Jan-Mar 2012 , Vol 33 ,Issue 1,pg.110-113</ref>
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*In a clinical study, it is observed that majja [[basti]] (therapeutic enema with bone marrow) along with oral intake of asthi shrinkhala(Cissus quadrangularis) shows encouraging results in the management of osteoporosis (asthi-majjakshaya) and it also improves the general health of the patients.<ref>Ajay K. Gupta et al, Effect of Majja Basti (therapeutic enema) and Asthi Shrinkhala (Cissus quadrangularis) in the management ofOsteoporosis (Asthi-Majjakshaya),AYU , Jan-Mar 2012 , Vol 33 ,Issue 1,pg.110-113</ref>
=== Further scope of research ===
=== Further scope of research ===
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The list of references for majja dhatu in Charak Samhita can be seen [[Media:Majja_dhatu-reference_list.pdf|here.]]
The list of references for majja dhatu in Charak Samhita can be seen [[Media:Majja_dhatu-reference_list.pdf|here.]]
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== References ==
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