Changes

Neurones Recorded in Vitro,” Neuroscience Letters 34:283-388, 1982.</ref>

Neurones Recorded in Vitro,” Neuroscience Letters 34:283-388, 1982.</ref>

The frequency of heart attacks peaks between 6 a.m. and noon asthma attacks are most prevalent at night, human babies are born predominantly in the early morning hours. While these patterns do not necessarily indicate that the events are driven by the circadian pacemaker, they do suggest temporal order in the functioning of the human body.  

The frequency of heart attacks peaks between 6 a.m. and noon<ref>Muller, J.E., Stone, P.H., Turin, Z.G., et al., “The Milis Study Group: Circadian Variation in the Frequency of Onset of Acute Myocardial Infarction,” New England Journal of Medicine 313:1315-

1322, 1985.</ref> asthma attacks are most prevalent at night, human babies are born predominantly in the early morning hours. While these patterns do not necessarily indicate that the events are driven by the circadian pacemaker, they do suggest temporal order in the functioning of the human body.  

This temporal organization appears to be beneficial; the human body is prepared for routine changes in state, such as awakening each morning, rather than simply reacting after shifts in demand. In addition, these regular cycles in the body present considerations for diagnosis of health problems and for the timing of medical treatment   

This temporal organization appears to be beneficial; the human body is prepared for routine changes in state, such as awakening each morning, rather than simply reacting after shifts in demand. In addition, these regular cycles in the body present considerations for diagnosis of health problems and for the timing of medical treatment