Changes

'''Eccrine glands:''' These are the common sweat glands distributed all over the body, especially over the thick skin. The eccrine sweat gland is basically of tubular structure which at beginning is in the deeper part of dermis and is highly coiled. The rest of the gland courses through the dermis- epidermis- open to the exterior. Sweat forms by coiled portion. These are functional throughout the life. These are present largely over the back and chest regions. [Hutchinson’s Clinical Methods.p.512]<ref name=Hutch>Swash M, Glynn M, Hutchinson’s Clinical Methods, 22nd Edition, Saunders Elsevier, USA.</ref>

'''Eccrine glands:''' These are the common sweat glands distributed all over the body, especially over the thick skin. The eccrine sweat gland is basically of tubular structure which at beginning is in the deeper part of dermis and is highly coiled. The rest of the gland courses through the dermis- epidermis- open to the exterior. Sweat forms by coiled portion. These are functional throughout the life. These are present largely over the back and chest regions. [Hutchinson’s Clinical Methods.p.512]<ref name=Hutch>Swash M, Glynn M, Hutchinson’s Clinical Methods, 22nd Edition, Saunders Elsevier, USA.</ref>

When synthesized the sweat is isotonic, but while moving towards the exterior, some sodium ions are reabsorbed. In case of  severe sweating, this reabsorption is more intense due to the action of aldosterone. The thermoregulation via sweating occurs through the eccrine glands innervated by sympathetic cholinergic fibres. The eccrine sweat is basically made up of water and sodium chloride (NACl). It may also contain mixture of many other chemicals from the interstitial fluid as well. The amount of sodium and cholride in the eccrine sweat is considered to be less, 60mmol/L and 70 mmol/L respectively.<ref name=Guyton/>

When synthesized the sweat is isotonic, but while moving towards the exterior, some sodium ions are reabsorbed. In case of  severe sweating, this reabsorption is more intense due to the action of aldosterone. The thermoregulation via sweating occurs through the eccrine glands innervated by sympathetic cholinergic fibres. The eccrine sweat is basically made up of water and sodium chloride (NACl). It may also contain mixture of many other chemicals from the interstitial fluid as well. The amount of sodium and cholride in the eccrine sweat is considered to be less, 60 mmol/L and 70 mmol/L respectively.<ref name=Guyton/>

'''Apocrine glands:''' These glands are located deep in subcutaneous layer in limited areas like axilla (armpit), pubic region, around the nipple of breast, scalp. The activity of apocrine glands increases with the onset of puberty and declines at old age. This process shows that these glands have got some relationship with reproductive physiology. The secretion from apocrine glands is odorless but bacterial decomposition makes it odorous, secretion show cyclic changes in females with menstrual cycle. These glands are structurally similar to eccrine glands, but are larger. Their coiled region lies within the subcutaneous tissue rather than the dermis.<ref>Pocock G et.al. Human Physiology, Oxford Printing Press, Sweat glands, regulation of internal environment, part nine, Fifth Edition, 2018, Page No.655-657</ref> In contrast to the eccrine glands, apocrine glands produce vicious, lipid rich sweat comprising of proteins, sugars and ammonia.

'''Apocrine glands:''' These glands are located deep in subcutaneous layer in limited areas like axilla (armpit), pubic region, around the nipple of breast, scalp. The activity of apocrine glands increases with the onset of puberty and declines at old age. This process shows that these glands have got some relationship with reproductive physiology. The secretion from apocrine glands is odorless but bacterial decomposition makes it odorous, secretion show cyclic changes in females with menstrual cycle. These glands are structurally similar to eccrine glands, but are larger. Their coiled region lies within the subcutaneous tissue rather than the dermis.<ref>Pocock G et.al. Human Physiology, Oxford Printing Press, Sweat glands, regulation of internal environment, part nine, Fifth Edition, 2018, Page No.655-657</ref> In contrast to the eccrine glands, apocrine glands produce vicious, lipid rich sweat comprising of proteins, sugars and ammonia.