Changes

''Majja dhatu'' is not vitiated to maximum extent but ''vata'' causes its ''kshaya'' i.e. depletion. Thus vitiated ''majja'' produces symptoms like ''netragaurava'' (heaviness in eyes), ''angagaurava''(heaviness in body) in patient of ''madhumeha''. The ketone bodies production due to excessive utilization of fat may be referred to ''dushti'' of ''vasa'' and ''majja''. ''Murchcha'' (temporary loss of consciousness) occurs due to dushti of ''majja'' in diabetes mellitus. The condition of hyperglycemic coma is characterized by the accumulation of ketone bodies.

''Majja dhatu'' is not vitiated to maximum extent but ''vata'' causes its ''kshaya'' i.e. depletion. Thus vitiated ''majja'' produces symptoms like ''netragaurava'' (heaviness in eyes), ''angagaurava''(heaviness in body) in patient of ''madhumeha''. The ketone bodies production due to excessive utilization of fat may be referred to ''dushti'' of ''vasa'' and ''majja''. ''Murchcha'' (temporary loss of consciousness) occurs due to dushti of ''majja'' in diabetes mellitus. The condition of hyperglycemic coma is characterized by the accumulation of ketone bodies.

==== ''Shukra'' ====

===== ''Shukra'' =====

''Shukra'' also get vitiated in the pathogenesis and produces symptoms like ''daurbalya'' (fatigue) and ''krichavyavayata'' (difficulty in sexual intercourse), because normal functions of ''shukra'' is to maintain ''dehabala''. It also plays role in the precipitation of ''sahaja'' (genetic) ''prameha''. Sexual impotency and testicular hypofuctions have been reported in diabetes mellitus.

''Shukra'' also get vitiated in the pathogenesis and produces symptoms like ''daurbalya'' (fatigue) and ''krichavyavayata'' (difficulty in sexual intercourse), because normal functions of ''shukra'' is to maintain ''dehabala''. It also plays role in the precipitation of ''sahaja'' (genetic) ''prameha''. Sexual impotency and testicular hypofuctions have been reported in diabetes mellitus.