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|keywords= Shat-kriya Kala, Shat-kriya Kala in Ayurveda, Six progressive stages of disease for treatment interventions, charak samhita, caraka samhita, Indian system of medicine, pathogenesis of disease  
 
|keywords= Shat-kriya Kala, Shat-kriya Kala in Ayurveda, Six progressive stages of disease for treatment interventions, charak samhita, caraka samhita, Indian system of medicine, pathogenesis of disease  
|description=Prevention of disease occurrence and recurrence  
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|description= These are six stages of progression of disease important to prevent disease occurrence and recurrence
|image=http://www.carakasamhitaonline.com/mediawiki-1.32.1/resources/assets/ogimgs.jpg
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|image=http://www.carakasamhitaonline.com/resources/assets/ogimgs.jpg
 
|image_alt=carak samhita
 
|image_alt=carak samhita
 
|type=article
 
|type=article
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|label1 = Section/Chapter/topic
 
|label1 = Section/Chapter/topic
|data1 = [[Nidana]] / [[Vyadhi]] / Shatkriyakala
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|data1 = Concepts and Contemporary Practices-[[Nidana]] / [[Vyadhi]] / Shatkriyakala
    
|label2 = Authors
 
|label2 = Authors
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|label7 = Date of first publication:
 
|label7 = Date of first publication:
 
|data7 = August 31, 2020
 
|data7 = August 31, 2020
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|label8 = DOI
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|data8 = [https://doi.org/10.47468/CSNE.2020.e01.s09.028 10.47468/CSNE.2020.e01.s09.028]
 
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* Sensible suitable use of senses ([[satmya]] indriyartha)
 
* Sensible suitable use of senses ([[satmya]] indriyartha)
 
* Intact intelligence, patience & memory (pragya)
 
* Intact intelligence, patience & memory (pragya)
* The empowered state of body mind and digestion (Deha bala, chetas bala & [[agni]] bala)
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* The empowered state of body mind and digestion (deha bala, chetas bala & [[agni]] bala)
 
* Followings expert’s advice (aptopsevi)
 
* Followings expert’s advice (aptopsevi)
 
* Charity & truthfulness (data & satyaparata) etc.
 
* Charity & truthfulness (data & satyaparata) etc.
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=== VI. Stage of differentiation/ termination (bheda)===
 
=== VI. Stage of differentiation/ termination (bheda)===
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[[File:Stages of disease progression.jpg|500px|'''Figure 2: Six Stages of disease evolution and management interventions'''|thumb]]
    
This is the stage of differentiation/ termination/ rehabilitation of symptomatology. In this stage, disease becomes sub-acute, chronic, or incurable. When disease further progresses, it may produce complications becoming incurable or severe complications leading to death or may cause temporary/ permanent disability. Otherwise in self-limiting disorders, the disease may get cured itself by body and rehabilitation will be required. This is the last opportunity of the management, where all the possible management is to be applied.
 
This is the stage of differentiation/ termination/ rehabilitation of symptomatology. In this stage, disease becomes sub-acute, chronic, or incurable. When disease further progresses, it may produce complications becoming incurable or severe complications leading to death or may cause temporary/ permanent disability. Otherwise in self-limiting disorders, the disease may get cured itself by body and rehabilitation will be required. This is the last opportunity of the management, where all the possible management is to be applied.
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* With strong therapeutic interventions, the health might be restored without disability.
 
* With strong therapeutic interventions, the health might be restored without disability.
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====Suggested as rehabilitative therapies or prakriti Sthapana====
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====Suggested as rehabilitative therapies or prakriti sthapana====
    
* Prevent/limit the complications
 
* Prevent/limit the complications
 
* Prevent genetic transmissions to offspring
 
* Prevent genetic transmissions to offspring
 
* Rehabilitation of disabilities
 
* Rehabilitation of disabilities
* Rejuvenation for nonoccurence of diseases
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* Rejuvenation for nonoccurrence of diseases
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== Bibliography ==
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===Summary===
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Thus the clinical observations, pathological events, treatment interventions and intensity of host:antigen interactions can be summarized as shown in figure 2. The Ayurvedic concept of the six stages of disease is one of the most important factors distinguishing Ayurveda from Allopathy. During the first four stages, disease symptoms may be subtle or nonexistent. In Allopathy, in these stages when there is no clear feature of diseases and symptoms are subjective, the patients are usually labeled as "functional," "hypochondriac" or "neurotic" until the full manifestations of the disease develop. However, in Ayurveda, the physician can identify the imbalance at an early stage.  These Ayurvedic assumptions are not just baseless ideologies. Modern science bears out the validity of these assumptions.<ref>Basisht GK. Symbiohealth-Need of the hour. AYU [serial online] 2011 [cited 2020 Sep 21];32:6-11. Available from: http://www.ayujournal.org/text.asp?2011/32/1/6/85715</ref> The three body types with dominance of dosha are validated by a biostatistical study of large populations with 90 percent certainty.<ref>Joshi RR. A biostatistical approach to Ayurveda: Quantifying the Tridosha. J Altern Complement Med 2004;10:879-89.</ref> Certain genetic traits are more susceptible for diseases is shown by genome research. This principles applies to suitability of a person to certain drugs, too.<ref>Anne Barton, MRCP, Ph D, E Text book, Available from: http://www.Uptodate.com [Last cited on 2011 Jan 28]</ref> Just as Ayurveda has been able to predict which people are more likely to suffer from a particular disease. Recent research has also shown that lifestyle changes can "turn off" and "turn on" certain genes, and thus, with effort, we can turn off bad genes and turn on the good ones. <ref>Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, et al. Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial. Lancet 1990;336:129-33.</ref> Therefore, understanding concept of shatkriyakala is highly important in clinical practice.
    
=== Abbreviations ===
 
=== Abbreviations ===
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Cha. = Charak,  Su. = Sushruta,  Sa. = Samhita, A. = Ashtanga,  Hr.= Hridayam
 
Cha. = Charak,  Su. = Sushruta,  Sa. = Samhita, A. = Ashtanga,  Hr.= Hridayam
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=== Related links ===  
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=== Related articles ===  
    
[[Kha vaigunya]]
 
[[Kha vaigunya]]
    
== References ==
 
== References ==
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