Changes

===Summary===

===Summary===

Thus the clinical observations, pathological events, treatment interventions and intensity of host:antigen interactions can be summarized as shown in figure 2. The Ayurvedic concept of the six stages of disease is one of the most important factors distinguishing Ayurveda from Allopathy. During the first four stages, disease symptoms may be subtle or nonexistent. In Allopathy, in these stages when there is no clear feature of diseases and symptoms are subjective, the patients are usually labeled as "functional," "hypochondriac" or "neurotic" until the full manifestations of the disease develop. However, in Ayurveda, the physician can identify the imbalance at an early stage.  These Ayurvedic assumptions are not just baseless ideologies. Modern science bears out the validity of these assumptions.<ref>Basisht GK. Symbiohealth-Need of the hour. AYU [serial online] 2011 [cited 2020 Sep 21];32:6-11. Available from: http://www.ayujournal.org/text.asp?2011/32/1/6/85715</ref> The three body types with dominance of dosha are validated by a biostatistical study of large populations with 90 percent certainty.<ref>Joshi RR. A biostatistical approach to Ayurveda: Quantifying the Tridosha. J Altern Complement Med 2004;10:879-89.</ref> Certain genetic traits are more susceptible for diseases is shown by genome research. This principles applies to suitability of a person to certain drugs, too.<ref>Anne Barton, MRCP, Ph D, E Text book, Available from: http://www.Uptodate.com [Last cited on 2011 Jan 28]</ref> Just as Ayurveda has been able to predict which people are more likely to suffer from a particular disease. Recent research has also shown that lifestyle changes can "turn off" and "turn on" certain genes, and thus, with effort, we can turn off bad genes and turn on the good ones. <ref>Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, et al. Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial. Lancet 1990;336:129-33.</ref>

Thus the clinical observations, pathological events, treatment interventions and intensity of host:antigen interactions can be summarized as shown in figure 2. The Ayurvedic concept of the six stages of disease is one of the most important factors distinguishing Ayurveda from Allopathy. During the first four stages, disease symptoms may be subtle or nonexistent. In Allopathy, in these stages when there is no clear feature of diseases and symptoms are subjective, the patients are usually labeled as "functional," "hypochondriac" or "neurotic" until the full manifestations of the disease develop. However, in Ayurveda, the physician can identify the imbalance at an early stage.  These Ayurvedic assumptions are not just baseless ideologies. Modern science bears out the validity of these assumptions.<ref>Basisht GK. Symbiohealth-Need of the hour. AYU [serial online] 2011 [cited 2020 Sep 21];32:6-11. Available from: http://www.ayujournal.org/text.asp?2011/32/1/6/85715</ref> The three body types with dominance of dosha are validated by a biostatistical study of large populations with 90 percent certainty.<ref>Joshi RR. A biostatistical approach to Ayurveda: Quantifying the Tridosha. J Altern Complement Med 2004;10:879-89.</ref> Certain genetic traits are more susceptible for diseases is shown by genome research. This principles applies to suitability of a person to certain drugs, too.<ref>Anne Barton, MRCP, Ph D, E Text book, Available from: http://www.Uptodate.com [Last cited on 2011 Jan 28]</ref> Just as Ayurveda has been able to predict which people are more likely to suffer from a particular disease. Recent research has also shown that lifestyle changes can "turn off" and "turn on" certain genes, and thus, with effort, we can turn off bad genes and turn on the good ones. <ref>Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, et al. Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial. Lancet 1990;336:129-33.</ref> Therefore, understanding concept of shatkriyakala is highly important in clinical practice.

=== Abbreviations ===

=== Abbreviations ===