Changes

==Formation and metabolism of rakta dhatu==

==Formation and metabolism of rakta dhatu==

*The rakta dhatu is formed from its predecessor [[rasa dhatu]]. The nourishing portion of [[rasa dhatu]] and constituents of nutrient fluid (ahara rasa) are transformed into rakta dhatu by action of ranjakapitta (type of pitta responsible for colour pigments). [Cha. Sa. [[Chikitsa Sthana]] 15/28] This process takes place in liver and spleen.[Su.Sa.Sutra Sthana 14/4-5]

*The rakta dhatu is formed from its predecessor [[rasa dhatu]]. The nourishing portion of [[rasa dhatu]] and constituents of nutrient fluid (ahara rasa) are transformed into rakta dhatu by action of ranjakapitta (type of [[pitta]] responsible for colour pigments). [Cha. Sa. [[Chikitsa Sthana]] 15/28] This process takes place in liver and spleen.[Su.Sa.Sutra Sthana 14/4-5]

*The pure blood is formed as per the suitable conditions at the place of living, season, and adaptation. [Cha. Sa. [[Sutra Sthana]] 24/3]  

*The pure blood is formed as per the suitable conditions at the place of living, season, and adaptation. [Cha. Sa. [[Sutra Sthana]] 24/3]  

The liver acts as the major blood reservoir.  It stores about 450 milliliters or almost 10 percent of the body's total blood volume. This capacity can increase up to 1 litre in certain cases due to the expanding capacity of the liver. It synthesizes some proteins including coagulation factors I (fibrinogen), II (prothrombin), V, VII, VIII, IX, X, XI, XII, XIII, as well as protein C, protein S and antithrombin. All of these play important roles in blood physiology. Moreover, the liver is a major site of production for thrombopoietin, a glycoprotein hormone that regulates the production of platelets by the bone marrow. The liver plays a major role in glucose, protein, and lipids present in the blood. It also purifies and protects blood from harmful toxins, metabolites, and heavy metals.  

The liver acts as the major blood reservoir.  It stores about 450 milliliters or almost 10 percent of the body's total blood volume. This capacity can increase up to 1 litre in certain cases due to the expanding capacity of the liver. It synthesizes some proteins including coagulation factors I (fibrinogen), II (prothrombin), V, VII, VIII, IX, X, XI, XII, XIII, as well as protein C, protein S and antithrombin. All of these play important roles in blood physiology. Moreover, the liver is a major site of production for thrombopoietin, a glycoprotein hormone that regulates the production of platelets by the bone marrow. The liver plays a major role in glucose, protein, and lipids present in the blood. It also purifies and protects blood from harmful toxins, metabolites, and heavy metals.  

Thus, bone marrow is the site of formation of blood cells; whereas the liver is the major site in maturation of blood cells and maintaining the physiological status of blood tissue.  

Thus, bone marrow is the site of formation of blood cells; whereas the liver is the major site in maturation of blood cells and maintaining the physiological status of blood tissue.

==Metabolic byproducts and waste products (Upadhatu and mala):==

==Metabolic byproducts and waste products (Upadhatu and mala):==