Improper administration of emesis causes itching, urticaria etc. which can be considered as allergic reaction in response to the allergen in the form of emetic drug. The protein in the food is the most common allergic component. Some proteins or fragments of proteins are resistant to digestion and those that are not broken down in the digestive process are tagged by the Immunoglobulin E (IgE) causing allergic reaction. Possibility cannot be ruled out that the drug administered for emesis may irritate gastric mucosa, increases intracellular space due to transient inflammation thereby escaping into circulation directly without digestion and acts as a trigger for allergy. | Improper administration of emesis causes itching, urticaria etc. which can be considered as allergic reaction in response to the allergen in the form of emetic drug. The protein in the food is the most common allergic component. Some proteins or fragments of proteins are resistant to digestion and those that are not broken down in the digestive process are tagged by the Immunoglobulin E (IgE) causing allergic reaction. Possibility cannot be ruled out that the drug administered for emesis may irritate gastric mucosa, increases intracellular space due to transient inflammation thereby escaping into circulation directly without digestion and acts as a trigger for allergy. |