Changes

#Aqueous extract of fruits significantly lowered the serum bilirubin level in chlorpromazine – induced jaundice in rats<ref>SK Bapat, V Chandra, The effect of Luffa echinata (Roxb) on experimental jaundice in rats,Indian journal of physiology and pharmacology 08/1968; 12(3):119-20.</ref>

#Aqueous extract of fruits significantly lowered the serum bilirubin level in chlorpromazine – induced jaundice in rats<ref>SK Bapat, V Chandra, The effect of Luffa echinata (Roxb) on experimental jaundice in rats,Indian journal of physiology and pharmacology 08/1968; 12(3):119-20.</ref>

#The alcoholic and the ether extracts of the plant showed definite protection against CCl4- induced liver injury in rats.<ref>Lauria P etal, The effect of Luffa ecchinata in liver injury and its other pharmacological actions. Indian J Pharmacology 1972 ,4(2),152</ref>

#The alcoholic and the ether extracts of the plant showed definite protection against CCl4- induced liver injury in rats.<ref>Lauria P etal, The effect of Luffa ecchinata in liver injury and its other pharmacological actions. Indian J Pharmacology 1972 ,4(2),152</ref>

#Anonymous,Wealth of India- Raw materials Vol 6 L-M, CSIR, NewDelhi, pp-181<ref>Li-Hua Shang , Chun-Mei Li , Zhao-Yang Yang , De-Hai Che , Jing-Yan Cao  and Yan Yu, Luffa echinata Roxb. Induces Human Colon Cancer Cell (HT-29) Death by Triggering the Mitochondrial Apoptosis Pathway,  Molecules 2012, 17, 5780-5794</ref>

#Anonymous,Wealth of India- Raw materials Vol 6 L-M, CSIR, NewDelhi, pp-181

#50% ethanolic extract of whole plant (except roots) showed hypoglycaemic action in rats. The LD50 of the extract in mice was found to be 261 mg/kg i.p[14] (Aswal et al., 1984).

#50% ethanolic extract of whole plant (except roots) showed hypoglycaemic action in rats. The LD50 of the extract in mice was found to be 261 mg/kg i.p[14] (Aswal et al., 1984).

#Methanolic extract of Luffa echinata exerts its antiproliferative effects by inducing apoptotic cell death, and causing G2/S arrest in HT-29 cells and it promotes ROS generation<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>.  

#Methanolic extract of Luffa echinata exerts its antiproliferative effects by inducing apoptotic cell death, and causing G2/S arrest in HT-29 cells and it promotes ROS generation<ref>Li-Hua Shang , Chun-Mei Li , Zhao-Yang Yang , De-Hai Che , Jing-Yan Cao and Yan Yu, Luffa echinata Roxb. Induces Human Colon Cancer Cell (HT-29) Death by Triggering the Mitochondrial Apoptosis Pathway, Molecules 2012, 17, 5780-5794</ref>.  

#In a study on the therapeutic effect of Luffa echinata fruits in 6 patients of viral hepatitis the result reveals that a single administration of drops squeezed from water soaked dry fruits into the nostrils led to a reduction in bilirubin and SGPT levels significantly within 3 to 7 days and this response was accompanied by a substantial relief in clinical symptoms especially anorexia and malaise.The nasal secretions contained total bilirubin ranging from 1.62 to 5.5mg per cent, the levels not being higher than the serum levels. The observations thus could justify the simple explanation of the relief of jaundice by enhanced nasal excretion of bilirubin. The possibility of the absorption of the active principle of the plant through the nasal mucosa and then action on the liver has been proposed.<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>

#In a study on the therapeutic effect of Luffa echinata fruits in 6 patients of viral hepatitis the result reveals that a single administration of drops squeezed from water soaked dry fruits into the nostrils led to a reduction in bilirubin and SGPT levels significantly within 3 to 7 days and this response was accompanied by a substantial relief in clinical symptoms especially anorexia and malaise.The nasal secretions contained total bilirubin ranging from 1.62 to 5.5mg per cent, the levels not being higher than the serum levels. The observations thus could justify the simple explanation of the relief of jaundice by enhanced nasal excretion of bilirubin. The possibility of the absorption of the active principle of the plant through the nasal mucosa and then action on the liver has been proposed.<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>