Changes

#Methanolic extract of Luffa echinata exerts its antiproliferative effects by inducing apoptotic cell death, and causing G2/S arrest in HT-29 cells and it promotes ROS generation<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>.  

#Methanolic extract of Luffa echinata exerts its antiproliferative effects by inducing apoptotic cell death, and causing G2/S arrest in HT-29 cells and it promotes ROS generation<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>.  

#In a study on the therapeutic effect of Luffa echinata fruits in 6 patients of viral hepatitis the result reveals that a single administration of drops squeezed from water soaked dry fruits into the nostrils led to a reduction in bilirubin and SGPT levels significantly within 3 to 7 days and this response was accompanied by a substantial relief in clinical symptoms especially anorexia and malaise.The nasal secretions contained total bilirubin ranging from 1.62 to 5.5mg per cent, the levels not being higher than the serum levels. The observations thus could justify the simple explanation of the relief of jaundice by enhanced nasal excretion of bilirubin. The possibility of the absorption of the active principle of the plant through the nasal mucosa and then action on the liver has been proposed.<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>

#In a study on the therapeutic effect of Luffa echinata fruits in 6 patients of viral hepatitis the result reveals that a single administration of drops squeezed from water soaked dry fruits into the nostrils led to a reduction in bilirubin and SGPT levels significantly within 3 to 7 days and this response was accompanied by a substantial relief in clinical symptoms especially anorexia and malaise.The nasal secretions contained total bilirubin ranging from 1.62 to 5.5mg per cent, the levels not being higher than the serum levels. The observations thus could justify the simple explanation of the relief of jaundice by enhanced nasal excretion of bilirubin. The possibility of the absorption of the active principle of the plant through the nasal mucosa and then action on the liver has been proposed.<ref>K Nishteswar,  Ayurvedic herbal remedies, Choukhambha Surabharati Prakashan , Varanasi,2009, pp-95</ref>

#Pharmacological activity

 

'''Pharmacological activity'''

*Anti-arthritic activity <ref>H S Chandel et al, Evaluation of antiarthritic activity on LuffaechinataRoxb. fruits on rats, Asian Journal of Biomedical and Pharmaceutical Science, 3(21) 2013, 36-41.</ref>

*Anti-arthritic activity <ref>H S Chandel et al, Evaluation of antiarthritic activity on LuffaechinataRoxb. fruits on rats, Asian Journal of Biomedical and Pharmaceutical Science, 3(21) 2013, 36-41.</ref>

*Hepatoprotective activity<ref>Bahar Ahmed et al, Hepatoprotective activity of Luffaechinata fruits, Journal of Ethnopharmacology 76 (2001) 187–189</ref>

*Hepatoprotective activity<ref>Bahar Ahmed et al, Hepatoprotective activity of Luffaechinata fruits, Journal of Ethnopharmacology 76 (2001) 187–189</ref>