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Administration of drugs in emetic or purgative therapies and rest of the [[Panchakarma]] procedures, complication arising out of their improper administration and their successful management dealt in [[Siddhi Sthana]] (section on successful administration of therapeutic measures) in detail. Indications and contraindications of emetic and purgative therapies are described by preceptor in [[Siddhi Sthana]] (Chap.2/8-13)<ref>Ram karan Sharma and Vaidya Bhagwan Dash, Caraka Samhita, Vol VI, Sidhhisthana, Chap 2, shlok no.8-13, edition 2nd 2005,Chaukhamba Sanskrit Series Office, Varanasi, pp. 177-188.</ref>. Appearance of ''pitta'' at the end of emesis and ''kapha'' at the end of purgation though described under signs of proper elimination, Chakrapani opines that they may occur in inappropriate purification (''asamyakshudhhi''). Therefore additionally associated signs like emaciation (''karshya''), weakness (''daurbalya'') and lightness of the body (''laghavata'') only indicate appropriate purification.
 
Administration of drugs in emetic or purgative therapies and rest of the [[Panchakarma]] procedures, complication arising out of their improper administration and their successful management dealt in [[Siddhi Sthana]] (section on successful administration of therapeutic measures) in detail. Indications and contraindications of emetic and purgative therapies are described by preceptor in [[Siddhi Sthana]] (Chap.2/8-13)<ref>Ram karan Sharma and Vaidya Bhagwan Dash, Caraka Samhita, Vol VI, Sidhhisthana, Chap 2, shlok no.8-13, edition 2nd 2005,Chaukhamba Sanskrit Series Office, Varanasi, pp. 177-188.</ref>. Appearance of ''pitta'' at the end of emesis and ''kapha'' at the end of purgation though described under signs of proper elimination, Chakrapani opines that they may occur in inappropriate purification (''asamyakshudhhi''). Therefore additionally associated signs like emaciation (''karshya''), weakness (''daurbalya'') and lightness of the body (''laghavata'') only indicate appropriate purification.
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In seminar held on the topic of “Determination of appropriateness of medicaments for enema” (Siddhi 11). Saunaka said “Amongst the fruits, ''Jimutaka'' is the foremost in efficacy for ''basti'' (medicated enema) because of its effect to eliminate ''kapha'' and ''pitta''”. Atreya concluded that ''Jimutaka'' is useful for the treatment of ''kushtha'' (skin diseases including leprosy), while ''Madanaphala'' is not contraindicated in any disease. He further writes that there is no drug that is absolutely free from any side effects - good or bad. One has to think of a drug which possesses more of good attributes in the treatment of a particular ailment.[6] To make it more explicit the physician has to judiciously evaluate ''rogibala'' (strength of patient) and ''rogabala'' (severity of disease) to draft suitable therapeutic regimens.
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In seminar held on the topic of “Determination of appropriateness of medicaments for enema” (Siddhi 11). Saunaka said “Amongst the fruits, ''Jimutaka'' is the foremost in efficacy for ''basti'' (medicated enema) because of its effect to eliminate ''kapha'' and ''pitta''”. Atreya concluded that ''Jimutaka'' is useful for the treatment of ''kushtha'' (skin diseases including leprosy), while ''Madanaphala'' is not contraindicated in any disease. He further writes that there is no drug that is absolutely free from any side effects - good or bad. One has to think of a drug which possesses more of good attributes in the treatment of a particular ailment.<ref>Ram karan Sharma and Vaidya Bhagwan Dash, Caraka Samhita, Vol VI, Sidhhisthana, Chap 11, shlok no.5, 6, 10-14, edition 2nd 2005,Chaukhamba Sanskrit Series Office, Varanasi, pp. 382-84.</ref> To make it more explicit the physician has to judiciously evaluate ''rogibala'' (strength of patient) and ''rogabala'' (severity of disease) to draft suitable therapeutic regimens.
    
Atreya enumerated three synonyms of ''Jimutaka'' i.e. ''garagari, veni'' and ''devatadaka''. Bhavamishra described ''Jimutaka'' (''Guduchyadivarga'') with synonyms like ''Devadali, Karkati'' and ''Vrittakosha'' in addition to Charaka’s descriptions. He has also quoted another variety known as ''Peetadevadali'' with synonyms ''Kharasparsha, Vishaghni'' and ''Garanashini''. ''Devadali'' is attributed with ''vamaka'' activity and its fruit is mentioned as ''Samsrana''. Indications include ''Arsha, Pandu, Kshaya, Hikka, Jwara, Krimi, Gulma'' and ''Shoola''. The recipe with ''Jimutaka'' as nasal drops in the management of ''Kamala'' is very popular and scientific validation has been produced for its claim. Botanical source of ''Jimutaka'' are Luffa echinata and Luffa graveolens (yellow variety).
 
Atreya enumerated three synonyms of ''Jimutaka'' i.e. ''garagari, veni'' and ''devatadaka''. Bhavamishra described ''Jimutaka'' (''Guduchyadivarga'') with synonyms like ''Devadali, Karkati'' and ''Vrittakosha'' in addition to Charaka’s descriptions. He has also quoted another variety known as ''Peetadevadali'' with synonyms ''Kharasparsha, Vishaghni'' and ''Garanashini''. ''Devadali'' is attributed with ''vamaka'' activity and its fruit is mentioned as ''Samsrana''. Indications include ''Arsha, Pandu, Kshaya, Hikka, Jwara, Krimi, Gulma'' and ''Shoola''. The recipe with ''Jimutaka'' as nasal drops in the management of ''Kamala'' is very popular and scientific validation has been produced for its claim. Botanical source of ''Jimutaka'' are Luffa echinata and Luffa graveolens (yellow variety).

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