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''Vata anulomanam'' means to facilitate the ''gati'' (motion) of ''vata'' downwards to anus. Among five types of ''vata, samana'' and ''apana'' have major role in diseases like ''arsha, atisara'' and ''grahanidosha''. Obstruction to movement of ''vata'' (''avarudha gati'') or diarrhea (''atisaraṇa'') leads to ''agni kshaya''. ''Avarudha gati'' is the cause for ''vibandha'' (constipation), ''malavibandha'' (obstruction to feces) along with ''pravahana'' (urge to defecate) which increases the intra-lumen pressure leading to incompetency of valves in rectal veins leading to their varicosity which causes hemorrhoids where as ''atisarana'' (diarrhea) causes increased motility of intestine. Hence ''vata anulomanam'' should not be understood as ''virechana'' or laxation but regularization of ''vata gati'' so that there is no ''avarodha'' or ''atisarana''. The same concept of ''vata anulomana'' is also mentioned in [[Grahani Chikitsa]].(Ca.Ci.14/247)
 
''Vata anulomanam'' means to facilitate the ''gati'' (motion) of ''vata'' downwards to anus. Among five types of ''vata, samana'' and ''apana'' have major role in diseases like ''arsha, atisara'' and ''grahanidosha''. Obstruction to movement of ''vata'' (''avarudha gati'') or diarrhea (''atisaraṇa'') leads to ''agni kshaya''. ''Avarudha gati'' is the cause for ''vibandha'' (constipation), ''malavibandha'' (obstruction to feces) along with ''pravahana'' (urge to defecate) which increases the intra-lumen pressure leading to incompetency of valves in rectal veins leading to their varicosity which causes hemorrhoids where as ''atisarana'' (diarrhea) causes increased motility of intestine. Hence ''vata anulomanam'' should not be understood as ''virechana'' or laxation but regularization of ''vata gati'' so that there is no ''avarodha'' or ''atisarana''. The same concept of ''vata anulomana'' is also mentioned in [[Grahani Chikitsa]].(Ca.Ci.14/247)
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Therefore, the line of treatment used in arśha with regard to agni bala and vāta anulomana is basically similar to that of grahaṇīdōṣha hence Charaka has explained grahaṇī dōṣa chikitsā adhyāya after arśa chikitsā adhyāya.( Chakrapani  Ca.Ci.15/1) Caraka could have restricted the name of chapter to grahaṇīchikitsā i.e. treatment of the avayava grahaṇī whereas he has increased the scope of chapter by using the word grahaṇīdōṣha.(Chakrapani  Ca.Ci.15/1).
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Therefore, the line of treatment used in ''arsha'' with regard to ''agni bala'' and ''vata anulomanam'' is basically similar to that of ''grahanidosha'' hence Charaka has explained [[Grahani Chikitsa]] after [[Arsha Chikitsa]].( Chakrapani  Ca.Ci.15/1) Charaka could have restricted the name of chapter to [[Grahani Chikitsa]] i.e. treatment of the ''avayava grahani'' whereas he has increased the scope of chapter by using the word ''grahanidosha''.(Chakrapani  Ca.Ci.15/1).
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There is always an inter-relationship between avayava (organ) and avayavi (part of organ) or ashraya(seat) and ashrayi (seated). Either of the one has an impact on the other, hence if grahaṇīavayava is in normal state then agni the avayavi functions normally and vice versa also holds true, whereas if dusti of grahaṇī takes place agni vaishamyata (imbalance) is seen e.g. ileitis, wherein digestion is hampered. grahaṇī is the seat for jatharāgni. (Ca.Ci.15 /56) Agni is responsible for ayu (longevity of life), varṇa (complexion), bala (strength), svāasthya (health), utsāha (enthusiasm), upachaya (proper metabolism), prabhā (glow) and oja (core energy). Prākṛta agni (normal digestive power) is essential for long and healthy life while, vitiated agni is responsible for roga avasthā (disease).(Ca. Ci. 15/3-4)  
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There is always an inter-relationship between ''avayava'' (organ) and ''avayavi'' (part of organ) or ''ashraya''(seat) and ''ashrayi'' (seated). Either of the one has an impact on the other, hence if ''grahaniavayava'' is in normal state then ''agni'' the ''avayavi'' functions normally and vice versa also holds true, whereas if ''dusti'' of ''grahani'' takes place ''agni vaishamyata'' (imbalance) is seen e.g. ileitis, wherein digestion is hampered. ''Grahani'' is the seat for ''jatharagni''. (Ca.Ci.15 /56) ''Agni'' is responsible for ''ayu'' (longevity of life), ''varna'' (complexion), ''bala'' (strength), ''svasthya'' (health), ''utsaha'' (enthusiasm), ''upachaya'' (proper metabolism), ''prabha'' (glow) and ''oja'' (core energy). ''Prakrita agni'' (normal digestive power) is essential for long and healthy life while, vitiated ''agni'' is responsible for ''roga avastha''(disease).(Ca. Ci. 15/3-4)  
In this chapter, Caraka describes formation of body tissues in detail with the role of ahara which is supplied continuously to maintain homeostasis. Vyāna vāta is promoter of rasa raktādi circulation.( Ca. Ci. 15/36)  It transports rasa raktādi drava dhātu throughout body continuously and as per metabolic demand. This explanation shows that closed circulation in human was known to Caraka.
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In this chapter, Charaka describes formation of body tissues in detail with the role of ahara which is supplied continuously to maintain homeostasis. Vyāna vāta is promoter of rasa raktādi circulation.( Ca. Ci. 15/36)  It transports rasa raktādi drava dhātu throughout body continuously and as per metabolic demand. This explanation shows that closed circulation in human was known to Caraka.
 
Grahaṇī is prime place where digestion and absorption of ahara rasa takes place. Āhara rasa provides nutrition for the rasādi sapta dhātu, along-with three sharirik dōṣha and three manasik dōṣha. Nourishment of satva, raja and tama is influenced by sātvika, rājasik and tāmasik ahāra. Tāmasika and rājasik ahāra suppresses satva guna thereby causing alpa satva in individual, a common predisposing factor of psychiatric disorders for e.g. alpa satva as mentioned in unmāda (Ca. Ci. 9/5)In vātaja grahaṇīvyādhishankā (feeling of suffering from disease) manifests in patients with alpa satva.  
 
Grahaṇī is prime place where digestion and absorption of ahara rasa takes place. Āhara rasa provides nutrition for the rasādi sapta dhātu, along-with three sharirik dōṣha and three manasik dōṣha. Nourishment of satva, raja and tama is influenced by sātvika, rājasik and tāmasik ahāra. Tāmasika and rājasik ahāra suppresses satva guna thereby causing alpa satva in individual, a common predisposing factor of psychiatric disorders for e.g. alpa satva as mentioned in unmāda (Ca. Ci. 9/5)In vātaja grahaṇīvyādhishankā (feeling of suffering from disease) manifests in patients with alpa satva.  
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Homeostasis at cellular level and gross level is maintained by vāta, pitta and kapha in which digestive and metabolic contributions are due to agni.  This chapter has been dedicated to agni to understand the manner in which it gets vitiated by doṣha and accordingly the line of treatment for the agni dōṣha is explained. As the functions of agni take place in grahaṇī hence disease related to grahaṇī has been given the name.
 
Homeostasis at cellular level and gross level is maintained by vāta, pitta and kapha in which digestive and metabolic contributions are due to agni.  This chapter has been dedicated to agni to understand the manner in which it gets vitiated by doṣha and accordingly the line of treatment for the agni dōṣha is explained. As the functions of agni take place in grahaṇī hence disease related to grahaṇī has been given the name.
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Secondly, pāndu roga is due to alpatā of raktaposhaka sāra bhāga (Chakrapani Ca. Ci. 16/3-7)  and, one of the main causes of this alpatā is mal-digestion and mal-absorption which takes place in grahaṇī. It is well known fact, that various contributory factors for blood formation have their absorption in gastrointestinal tract such as folic acid, vitamin B12, iron, etc which if not absorbed causes anemia this is the reason why Caraka has placed this chapter in between arśha and pāndu roga.
 
Secondly, pāndu roga is due to alpatā of raktaposhaka sāra bhāga (Chakrapani Ca. Ci. 16/3-7)  and, one of the main causes of this alpatā is mal-digestion and mal-absorption which takes place in grahaṇī. It is well known fact, that various contributory factors for blood formation have their absorption in gastrointestinal tract such as folic acid, vitamin B12, iron, etc which if not absorbed causes anemia this is the reason why Caraka has placed this chapter in between arśha and pāndu roga.
  

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