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==Importance of concept in diagnosis:==
 
==Importance of concept in diagnosis:==
Dhatu have their respective srotas (systems). These srotas get affected due to vitiation of dosha and lead to diseases. Thus, dhatu are the site of lesion in view of diagnosis and target receptors in view of treatment.  
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Dhatu have their respective [[srotas]] (systems). These [[srotas]] get affected due to vitiation of [[dosha]] and lead to diseases. Thus, dhatu are the site of lesion in view of diagnosis and target receptors in view of treatment.  
    
The increase or decrease of dhatu is also assessed for diagnosis of specific disease. The vitiated dosha reside in dhatu and produce specific clinical features as observed in conditions of jwara and kushtha.  
 
The increase or decrease of dhatu is also assessed for diagnosis of specific disease. The vitiated dosha reside in dhatu and produce specific clinical features as observed in conditions of jwara and kushtha.  
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In view of prognosis, involvement of a particular dhatu has importance in prognosis also.
 
In view of prognosis, involvement of a particular dhatu has importance in prognosis also.
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In jwara, if doshas are located in rasa, rakta, mamsa and medas dhatu, the conditionsare curable; while if those are located in the asthi and majja dhatu, then conditions are difficult to treat. If vitiated doshaare located in shukra dhatu, the condition isincurable. [Cha.Sa. Chikitsasthana 3/75-83]
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In jwara, if doshas are located in [[rasa]], [[rakta]],[[ mamsa]] and [[medas]] dhatu, the conditionsare curable; while if those are located in the [[asthi]] and [[majja]] dhatu, then conditions are difficult to treat. If vitiated dosha are located in [[shukra]] dhatu, the condition is incurable. [Cha.Sa. Chikitsasthana 3/75-83]
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In the pathogenesis of prameha(obstinate urinary disorders) dosha ( kapha, pitta and vata,) along with  the ten factors called dushya i.e, medas, rakta, shukra, ambu (body fluid), vasa (muscle fat), lasika (lymph), majja, rasa, ojas  and mamsa  play the role.[Cha.Sa. Chikitsasthana 6/8].While considering the prognosis, “Tulyadushyata” (similarity between the characteristics of dosha and dushya) is a good sign of prognosis[Ashtanga Sangraha Sutra Sthana7/218]
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In the pathogenesis of prameha(obstinate urinary disorders) [[dosha]] ( [[kapha]], [[pitta]] and [[vata]]) along with  the ten factors called dushya i.e, [[medas]], [[rakta]], [[shukra]], ambu (body fluid), vasa (muscle fat), lasika (lymph),[[ majja]], [[rasa]], [[ojas]] and [[mamsa]] play the role.[Cha.Sa. Chikitsasthana 6/8].While considering the prognosis, “Tulyadushyata” (similarity between the characteristics of [[dosha]] and dushya) is a good sign of prognosis[Ashtanga Sangraha Sutra Sthana7/218]
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Pathology of kushtha(skin diseases) is related to deranged physiology of seven factors. They are vata, pitta and kapha doshas in aggravated state and dhatus, namely, tvak (since the skin is the organ in which rasa dhatu is present, tvak word is used instead of rasa dhatu), mamsa, shonita and lasika that get deranged due to aggravated dosha. Involvement of higher dhatu makes the disease more complicated. [Cha.Sa. Chikitsasthana 7/9-10]
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Pathology of kushtha(skin diseases) is related to deranged physiology of seven factors. They are [[vata]], [[pitta]] and [[kapha]] doshas in aggravated state and dhatus, namely, tvak (since the skin is the organ in which rasa dhatu is present, tvak word is used instead of [[rasa dhatu]]),[[ mamsa]], [[shonita]] and lasika that get deranged due to aggravated [[dosha]]. Involvement of higher dhatu makes the disease more complicated. [Cha.Sa. Chikitsasthana 7/9-10]
    
Visarpa (acute spreading erysepelas)also has involvement of seven dhatu which determine the prognosis of the condition. [Cha.Sa. Chikitsasthana 21/12]
 
Visarpa (acute spreading erysepelas)also has involvement of seven dhatu which determine the prognosis of the condition. [Cha.Sa. Chikitsasthana 21/12]
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