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The following are the guidelines for selection of an ideal partner as per Ayurveda.
 
The following are the guidelines for selection of an ideal partner as per Ayurveda.
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*The partner should be belonging to a different clan(gotra).[ Cha. Sa. Sharira Sthana 2/3]
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*The partner should be belonging to a different clan(gotra).[ Cha. Sa. [[Sharira Sthana]] 2/3]
    
*Consanguinity should be avoided.  
 
*Consanguinity should be avoided.  
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The genetic factors like defects in chromosomes or genes are explained in Ayurvedic classics in the concept of chromosomes/gene (beejabhaga) and genetic material-DNA (beejabhaga avayava). It is explained on the basis of maternal (matruja) and paternal (pitruja) factors.
 
The genetic factors like defects in chromosomes or genes are explained in Ayurvedic classics in the concept of chromosomes/gene (beejabhaga) and genetic material-DNA (beejabhaga avayava). It is explained on the basis of maternal (matruja) and paternal (pitruja) factors.
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If the genes in the chromosomes (beejabhaga) which are responsible for the formation of a particular organ get vitiated or mutated (vikruta), this will result in the improper formation of the respective organ.[Ch Sa [[Sharira Sthana]] 3/17]
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If the genes in the chromosomes (beejabhaga) which are responsible for the formation of a particular organ get vitiated or mutated (vikruta), this will result in the improper formation of the respective organ.[Cha. Sa. [[Sharira Sthana]] 3/17]
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When a woman gets conceived in a state that her ovum (shonita) and uterus (garbhashaya) were not completely vitiated but simply afflicted by the circulating aggravated [[doshas ]]because of her improper regimens, one or many of the organs of the fetus which derive from the maternal source get deformed. This is the explanation given for the congenital deformities in organs of maternal origin. [Cha. Sa. [[Sharira Sthana] 4/30]
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When a woman gets conceived in a state that her ovum (shonita) and uterus (garbhashaya) were not completely vitiated but simply afflicted by the circulating aggravated [[doshas ]]because of her improper regimens, one or many of the organs of the fetus which derive from the maternal source get deformed. This is the explanation given for the congenital deformities in organs of maternal origin. [Cha. Sa. [[Sharira Sthana]] 4/30]
    
The yoni vyapad namely “shandi” is an example for the abnormalities in gametes (beeja dushti) leading to the deformity of anatomical structures (ashaya) in fetus due to affliction of [[vata]]leading to the female progeny with underdeveloped primary and secondary sexual characters [Cha. Sa. [[Chikitsa Sthana]]30/34-35] which is generally correlated by many scholars with the chromosomal disorder known as “turner syndrome”.
 
The yoni vyapad namely “shandi” is an example for the abnormalities in gametes (beeja dushti) leading to the deformity of anatomical structures (ashaya) in fetus due to affliction of [[vata]]leading to the female progeny with underdeveloped primary and secondary sexual characters [Cha. Sa. [[Chikitsa Sthana]]30/34-35] which is generally correlated by many scholars with the chromosomal disorder known as “turner syndrome”.
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{| class="wikitable"
 
{| class="wikitable"
 
|-
 
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!!Female ! Vitiated factor ! Outcome !Possible modern co-relation
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!Female !! Vitiated factor !! Outcome !Possible modern co-relation
 
|-
 
|-
 
| ||Genes in maternal chromosomes(beejabhaga of shonita), responsible for the formation of uterus (garbhashaya) || female not capable of reproduction (vandhya) || Agenesis of uterus/adnexa leading to infertility
 
| ||Genes in maternal chromosomes(beejabhaga of shonita), responsible for the formation of uterus (garbhashaya) || female not capable of reproduction (vandhya) || Agenesis of uterus/adnexa leading to infertility
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Many health conditions are caused by the combined effects of multiple genes which are known as polygenic. It may be by the interactions between genes and the environment also.  
 
Many health conditions are caused by the combined effects of multiple genes which are known as polygenic. It may be by the interactions between genes and the environment also.  
Example- heart disease, type 2 diabetes, schizophrenia, certain types of cancer etc.  
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Example- heart disease, type 2 diabetes, schizophrenia, certain types of cancer etc.
    
==Defective genital organs and supportive structures in mother ==
 
==Defective genital organs and supportive structures in mother ==
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