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The time of administration of medicine is called as ‘Aushadha sevana kala’. The efficacy and safety of medicine vary as per the time of administration. Chrono-pharmacology deals with studies of biological rhythm dependencies of drugs regarding its pharmacological effects and/or pharmacokinetics/dynamics of drugs in both animals and humans.
The time of administration of medicine is called as ‘Aushadha sevana kala’. The efficacy and safety of medicine vary as per the time of administration. Chrono-pharmacology deals with studies of biological rhythm dependencies of drugs regarding its pharmacological effects and/or pharmacokinetics/dynamics of drugs in both animals and humans.
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In Ayurveda, different times of medicine administration are mentioned for pacification (shamana) therapies. [A. Hr. Sutra Sthana 13]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> The principle of circadian rhythm of [[dosha]], their influence on human physiology is considered to achieve highest active potential of a medicine. By applying this principle of chrono-pharmacology, maximum efficacy can be achieved even in smaller doses. Moreover, a single medicine can be used in different disorders as per biological rhythms and states of [[dosha]]. Thus, the requirement of medicine can be reduced to treat multiple disorders. Duration of medical treatment in chronic disorders can also be reduced.
In Ayurveda, different times of medicine administration are mentioned for pacification (shamana) therapies. [A. Hr. Sutra Sthana 13]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> The principle of circadian rhythm of [[dosha]], their influence on human physiology is considered to achieve highest active potential of a medicine. By applying this principle of chrono-pharmacology, maximum efficacy can be achieved even in smaller doses. Moreover, a single medicine can be used in different disorders as per biological rhythms and states of [[dosha]]. Thus, the requirement of medicine can be reduced to treat multiple disorders. Duration of medical treatment in chronic disorders can also be reduced.
This article describes the time of administration of medicine and its application in clinical practice.
This article describes the time of administration of medicine and its application in clinical practice.
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{{Infobox
{{Infobox
|label5 = Correspondence email:
|label5 = Correspondence email:
|data5 = carakasamhita@gmail.com
|data5 = draneesheg@gmail.com,
dryogeshdeole@gmail.com,
carakasamhita@gmail.com
|label6 = Date of publication
|label6 = Date of publication
|data6 = May 21, 2021
|data6 = May 21, 2021
|label7 = DOI
|label7 = DOI
|data7 = Awaited
|data7 = 10.47468/CSNE.2021.e01.s09.056
}}
}}
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==Synonyms==
==Synonyms==
==More information==
==More information==
[[Yonivyapat Chikitsa]]
[[Yonivyapat Chikitsa]] [[Chikitsa Sthana]]
==Abbreviations==
==Abbreviations==
==References==
==References==
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